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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
age way young
I am not old, but my young way was never the way to age. Charles Dickens
age church body
We devote the activity of our youth to revelry and the decrepitude of our old age to repentance: and we finish the farce by bequeathing our dead bodies to the chancel, which when living, we interdicted from the church. Charles Caleb Colton
age waste excess
The excesses of our youth are drafts upon our old age. Charles Caleb Colton
age matter fairytale
In a utilitarian age, of all other times, it is a matter of grave importance that fairy tales should be respected. Charles Dickens
age pay time-is-money
I've reached an age at which I'd rather pay more for something that "just works" than roll up my sleeves, reach for a spanner, and make it work. Time is money, and the older we get the less of it we've got left. Charles Stross
age amusement serious
Pleasure, so called, is the murderer of serious thought. This is the age of excessive amusement. Everybody craves for it, like a babe for its rattle! Charles Spurgeon
agents very-good turns
I knew with Snape I was working as a double agent, as it turns out, and a very good one at that. Alan Rickman
age towns my-family
Hee Haw was probably my biggest exposure to live music at a young age, because there wasn't any live music around my town and no one in my family played instruments. Alan Jackson
age golden golden-rule
Here's my Golden Rule for a tarnished age: Be fair with others, but keep after them until they're fair with you. Alan Alda
civilians holiday innocent preparing targeted
made more heinous in that they deliberately targeted innocent civilians preparing for holiday celebrations. Condoleezza Rice
civilians law methods rule warfare weapons
It is a rule of international law that weapons and methods of warfare which do not discriminate between combatants and civilians should never be used. Sean MacBride
civilians congress extend fed illegal loans members remain ripped
The Pentagon got fed up with its recruits getting ripped off by payday lenders and in 2007 got Congress to make it illegal to extend such loans to members of the military. But civilians remain fair game. Timothy Noah
civilians limit priorities protecting resources supporting
There is a limit on our resources and the priorities we have are protecting civilians and supporting the transitional process. Kemal Saiki
civilians defend
When things did go wrong for the IRA, when civilians were killed, I tried to put it in context, not defend it. Peter T. King
civilians combat healthy human hurt innocent otherwise race rid seems shame terrible war
It seems like such a terrible shame that innocent civilians have to get hurt in wars, otherwise combat would be such a wonderfully healthy way to rid the human race of unneeded trash. Fred Woodworth
civilians conflicts covering gaza injured iraq life passed
In my 20 years as a photographer, covering conflicts from Bosnia to Gaza to Iraq to Afghanistan, injured civilians and soldiers have passed through my life many times. Anja Niedringhaus
civilians government harm helping proud
Where else in the world is a government helping the civilians they harm in conflict? Marla was very proud of this fact, Peter Bergen
civilians distort people state trying
We are in control, they are in a state of hysteria. Losers, they think that by killing civilians and trying to distort the feelings of the people they will win. I think they will not win, those bastards. Mohammed Saeed al-Sahaf
facts may opinion
You may alter an opinion, but you cannot alter a # fact . Charles Spurgeon
factor growth leading robert since success thank valuable vision
We want to thank Robert for his valuable contribution to the Company's development and growth since its inception, ... His entrepreneurial vision has been a leading factor in our success to date. Glenn Parker
facts embarrassing theft
[A] great embarrassing fact… haunts all attempts to represent the market as the highest form of human freedom: that historically, impersonal, commercial markets originate in theft. David Graeber
facts economic globalization
Globalization is a fact of economic life Carlos Salinas de Gortari
facts sacred comment
Comment is free but facts are sacred. C. P. Scott
facts republican celebrate
Well, I'm celebrating the fact that Republicans are doing better with women. Cathy McMorris Rodgers
fact feels funny might mug people twice wake
I wake up every day and look at my own ugly mug in the mirror and don't think twice about it. The fact that other people might want to look at me still feels funny. It's flattering, but funny. Luke Bracey
fact positives truth
The positives are closure. The fact is we participated with an ineligible player. That's the truth. You can't sugar-coat that. Gene Smith
fact last proud
We are proud of the fact that we surpassed last year's donation. Robert Fraser
history who-we-are way
History is a guide to navigation in perilous times. History is who we are and why we are the way we are. David McCullough
history want done
No harm's done to history by making it something someone would want to read. David McCullough
history social shank
History is the shank of the social sciences. C. Wright Mills
history lafayette might
For women, history does not exist. Murasaki, Sappho, and Madame Lafayette might be their own contemporaries. Cesare Pavese
history want grants
Everyone wants to be Cary Grant. Even I want to be Cary Grant. Cary Grant
history
When you think about it, history is made to be broken. That's the way we look at it. E. Hicks
history lists surprise
History is merely a list of surprises. It can only prepare us to be surprised yet again. Kurt Vonnegut
history
History! Read it and weep! Kurt Vonnegut
history disposition efficacy
But the power of instruction is seldom of much efficacy, except in those happy dispositions where it is almost superfluous. Edward Gibbon
inevitably matter somebody
I can't give more than I have. It doesn't matter if I am the most beautiful person in the room. There is inevitably going to be somebody way shinier and more tan than my pasty self. Olivia Thirlby
inevitably sincerely whatever
Whatever you vividly imagine, ardently desire, sincerely believe, and enthusiastically act upon... must inevitably come to pass! Paul J. Meyer
inevitably loose scar
After having a baby, there will inevitably be something on your body - a mark, a scar or some loose skin - that wasn't there before. Constance Marie
inevitably lives pull
Poets can't resist the dramatic pull of their lives and so inevitably write autobiographical verse. John Barton
inevitably movies questions raise
Movies about space raise those questions of what we're doing here, and that inevitably introduces a spiritual dimension. Danny Boyle
inevitably needs rely remove user
If I rely on the user to remove metadata, a lot of that metadata is inevitably going to get through. It really needs to be automated. Michael Silver
inevitably options soon starting
Starting off, all options are always open, but as soon as you choose something, you inevitably limit yourself. If you go for B, A is out. Alva Noto
inevitably suppose
I suppose you inevitably fall into habits of expression. Seamus Heaney
inevitably watching
I was very much a latchkey kid. My parents would feel the back of the television to make sure I hadn't been watching it when they were gone, which inevitably I was. Jim Rash
innocent crime contradictory
You don't have many suspects who are innocent of a crime. That's contradictory. If a person is innocent of a crime, then he is not a suspect. Edwin Meese
innocent shots deserve
The more innocent they are, the more they deserve to be shot. Bertolt Brecht
innocent-person justice long
That it is better 100 guilty Persons should escape than that one innocent Person should suffer, is a Maxim that has been long and generally approved. Benjamin Franklin
innocent nobody people planning since
Since 1999 we've had 100,000 innocent people murdered in America. But nobody is planning on commemorating all those people killed. Michael Paranzino
innocent people proposal punish
This proposal would punish people who are innocent of any wrongdoing. Bill Hamilton
innocent naive save simple trying
She's still the same old simple Cindy. She's just as innocent and naive as ever, just trying to save the world again. Anna Faris
innocent position proven until
We're kind of in the position that everybody's innocent until proven guilty. Rick Watson
innocent miss reason
We don't have little Miss Innocent who was sprayed for no reason at all. Steven Cohen
innocent-person murder human-nature
But I know human nature, my friend, and I tell you that, suddenly confronted with the possibility of being tried for murder, the most innocent person will lose his head and do the most absurd things. Agatha Christie
remains whether
Whether this is sustainable remains to be seen. Tim Heekin
remains
We have cut the text, but what remains are Shakespeare's words. Edward Hall
remains
Film remains completely mystical and mysterious to me. Nicolas Roeg
remains uncertain
In a difficult and uncertain environment, Renault remains on track to meet its 2012 objective. Carlos Ghosn
remains
A painter once told me that I'm like the Khajuraho, which you see once but which remains with you forever. I thought that was exquisite. Vidya Balan
remains
My head is in India, yet my body remains in Britain. I straddle the world like a colossus. Like a 5ft. 7in. colossus. Sanjeev Bhaskar
remains
I don't know. That remains to be seen. Marty Schottenheimer
remains
'Vogue' remains while its fashion editors come and go. Azzedine Alaia
remains trend volatile
Here, we also have a very volatile indicator. The trend remains downward. I don't think that has changed. Stephane Deo
technology hands people
Technology is destructive only in the hands of people who do not realize that they are one and the same process as the universe. Alan Watts
technology civilization goal
...the materialism of modern civilization is paradoxically founded on a hatred of materiality, a goal-oriented desire to obliterate all natural limits through technology, imposing an abstract grid over nature. Alan Watts
technology fit lifestyle
The success of SYNC is another proof point that we are doing just that. We will continue to innovate and expand the capability of SYNC by integrating even more new technologies that fit our customers’ lifestyles. Alan Mulally
technology matter watches
It doesn't matter what the technology is - no one will watch a Peter Greenaway film anyway. Alan Parker
technology fields needs
The computing field is always in need of new cliches. Alan Perlis
technology thinking people
I think it is inevitable that people program poorly. Training will not substantially help matters. We have to learn to live with it. Alan Perlis
technology bird worms
In software systems it is often the early bird that makes the worm. Alan Perlis
technology two benefits
Technology is always a two-edged sword. It will bring in many benefits, but also many disasters. Alan Moore
technology amish kind
I'm remote from most technology to the point that I'm kind of Amish. Alan Moore
throughout visitors week
Throughout the first week of grand-opening festivities, well over 100,000 visitors are expected, Tom Ross
throughout
Throughout the ages, know Him as the One. Guru Nanak
throughout
We really have a lot of fun at these sessions, we all get along and kid around with each other throughout the job. Tara Strong
throughout work
I think the philosophy that we don't know as much as we think we know resonates throughout my work. Bob Mayer
throughout
My genetic autobiography can be found throughout my body. Craig Venter
throughout
My weight has been one of the most challenging things that I've had to deal with throughout my career. Kelly Price
throughout
I guess I reinvented myself about 18 times throughout my career. Mystikal
throughout
While my speech is getting better every day, throughout my recovery, I have been able to sing to some extent. Gabrielle Giffords
throughout trend
We don't want to get into a fouling-type game, which has been our trend throughout the year. Scott Skiles
true-love heart men
My heart is set, as firmly as ever heart of man was set on woman. I have no thought, no view, no hope, in life beyond her; and if you oppose me in this great stake, you take my peace and happiness in your hands, and cast them to the wind. Charles Dickens
true-friend ambition character
A high character might be produced, I suppose, by continued prosperity, but it has very seldom been the case. Adversity, however it may appear to be our foe, is our true friend; and, after a little acquaintance with it, we receive it as a precious thing - the prophecy of a coming joy. It should be no ambition of ours to traverse a path without a thorn or stone. Charles Spurgeon
true-friend sharks blood
There are no true friends in politics. We are all sharks circling, and waiting, for traces of blood to appear in the water. Alan Clark
true-knowledge sustenance
True knowledge without xperience is food without sustenance David Mitchell
true-friend thinking knows
The WORK 1.Is it true? 2.Can you absolutely know that it's true? 3.How do you react when you think that thought? 4.Who would you be without the thought? Byron Katie
true-friend love-you opposites
You know who your true friends are when things go wrong for you, but the opposite is also true. When things go well, the people who really love you are happy. Carlos Ruiz Zafon
true-identity people acting
I've scammed so many people throughout my whole life who never learned my true identity until I started acting. Charlie Bewley
true-love home causes
Well I never had a place that I could call my very own/That's all right, my love, 'cause you're my home. Billy Joel
true-friend select
True friends are families which you can select. Audrey Hepburn
war ambition mean
For what are the triumphs of war, planned by ambition, executed by violence, and consummated by devastation? The means are the sacrifice of many, the end, the bloated aggrandizement of the few. Charles Caleb Colton
war winning games
War is a game in which princes seldom win, the people never. Charles Caleb Colton
war hands fog
Mystery magnifies danger, as a fog the sun, the hand that warned Belshazzar derived its horrifying effect from the want of a body. Charles Caleb Colton
war writing fighting
Men will wrangle for religion, write for it, fight for it, die for it; anything but live for it. Charles Caleb Colton
war long body
Wars are to the body politic, what drams are to the individual. There are times when they may prevent a sudden death, but if frequently resorted to, or long persisted in, they heighten the energies only to hasten the dissolution. Charles Caleb Colton
war heart character
Why am I always at war with myself? Why have I told, as if upon compulsion, what I knew all along I ought to have withheld? Why am I making a friend of this woman beside me, in spite of the whispers against her that I hear in my heart? Charles Dickens
war believe blow
I believe that the heaviest blow ever dealt at liberty's head will be dealt by this nation in the ultimate failure of its example to the earth. Charles Dickens
war believe writing
There's a long-standing (50 year old) flame war within the field over whether it's "sci-fi" or "SF".SF has traditionally been looked down on by the literary establishment because, to be honest, much early SF was execrably badly written - but these days the significance of the pigeon hole is fading; we have serious mainstream authors writing stuff that is I-can't-believe-it's-not-SF, and SF authors breaking into the mainstream. If you view them as tags that point to shelves in bricks-and-mortar bookshops, how long are these genre categories going to survive in the age of the internet? Charles Stross
war writing spy
I like lassic British spy thrillers. Seriously. If the cold war was still on, that's something I'd be writing. Charles Stross
warfare kind terror
Warfare against civilians must never be answered in kind. Terror must never be answered with terror. Caleb Carr
warfare things-change
You do have to change things as warfare changes. Charles Schumer
warfare life-is malice
Life is a warfare against the malice of others. Baltasar Gracian
warfare behavior form
It was both fascinating and appalling to learn that chimpanzees were capable of hostile and territorial behavior that was not unlike certain forms of primitive human warfare. Jane Goodall
warfare
Warfare cannot be humanized. Albert Einstein
warfare damage terrorism
Asymmetrical warfare is a euphemism for terrorism, just like collateral damage is a euphemism for killing innocent civilians. Alan Dershowitz
warfare needs campaigns
We need to make sure that whenever we're engaging in a cyber-warfare campaign, a cyber-espionage campaign in the United States, that we understand the word cyber is used as a euphemism for the internet, because the American public would not be excited to hear that we're doing internet warfare campaigns, internet espionage campaigns, because we realize that we ourselves are impacted by it. Edward Snowden
warfare
I think it will be warfare in the Senate. Cecilia Munoz
warfare surrender logical
The logical end to defensive warfare is surrender. Napoleon Bonaparte