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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
albeit fulfilling
We feel that we're fulfilling part of his wishes, albeit 199 years later, William Walsh
albeit bound breach consumers current economy few level matter next numbers percent spending suggest view
With unemployment set to breach 6 percent over the next few months, people's view of the current economy is bound to deteriorate, ... But expectations are what matter for spending, and at this level the numbers suggest consumers spending will rise, albeit not rapidly. Ian Shepherdson
albeit assess concur days decision economic entire executive hope however local mean ruling tender turn viability views
We're not celebrating just yet because this is only the first step, albeit a very important one. The Executive have 28 days to make their ruling but we would hope they would concur with the views of the local councilors. What this decision does mean however is that we can now go out to tender which in turn allows us to assess the economic viability of the entire project. Bill Farnsworth
albeit both bottom fiction funny hard love memoir true unique
I love writing both fiction and memoir. Both have unique challenges; bottom line, fiction is hard because you have to come up with the credible, twisty plot, and memoir is hard because you have to say something true and profound, albeit in a funny way. Lisa Scottoline
albeit dynamite felt grim invented nobel peace prize
The Nobel Peace Prize has always been a joke - albeit a grim one. Alfred Bernhard Nobel famously invented dynamite and felt sorry about it. P. J. O'Rourke
albeit softer
The RBA retains its tightening bias, albeit softer than in November. Bill Evans
albeit asks attractive dollar face levels players rush selling technical
One asks how can players rush into selling the dollar -- albeit at these attractive technical levels -- in the face of the Fed's bolstering, anti-inflation rhetoric? Ashraf Laidi
albeit caused colleagues comments john lesson people private sorry subjects
No one is sorrier than John for the embarrassment that these albeit private e-mails caused to his colleagues and to the people who were the subjects of those comments. John would be the first to say this has been a real lesson to him. John is abjectly sorry for all the comments that have come to light, and that's appropriate. Jeffrey Schneider
albeit full
My head was full of tidying tips, and I had complete, albeit misguided, confidence that I could tidy any place. Marie Kondo
bothering-you bother ifs
If something is bothering you, keep it to yourself. David Strickland
both discovery driven east finds fossil mary since understand
With the discovery of Zinjanthropus at Olduvai Gorge in 1959, my grandmother Mary Leakey pioneered the research in East Africa with my grandfather Louis. Many more spectacular fossil finds have since been made, both in Africa and elsewhere, by many researchers driven to understand our past. Louise Leakey
both since
Wendy and I both wanted kids, but since we were pushing 40, the clock was ticking. Lisa Cholodenko
both feed suffice
I care not to debate which came first, Islamism or anti-Muslim bigotry; suffice to say that both feed into each other symbiotically. Maajid Nawaz
both direct guess project serious
There is a healthy fraternal rivalry, but nothing serious and we both have been looking for a project to do together. I guess he may direct me in a project some day. Mackenzie Astin
both country english federal issue kinds language laws learn official people practical side state
The other side said (there are) 799 federal and state laws mandating the use of English. ... We would say those kinds of laws are not at issue here. I think that English is the official language of this country in a practical sense already. And I think that most people who come here both learn English and want to learn English. Richard Cohen
both checks dressing great knows reason rooms sit sound together worse
The other reason Rufus and I are great together is that we're both really lazy. The rehearsing, the sound checks -- he's actually worse than I am, and that's something. To get us to do anything other than sit in our dressing rooms is a challenge. Who knows what will happen? Ben Folds
both potential
The potential is unbelievable with both those girls. Duncan Chase
both huge potential sales
The potential is huge for them both in sales and production. Tarun Das
data people needs
People will come to your site because you have good compelling content. You need to hit it from all angles: blog posts, articles, graphs, data, infographics, interactive content - even short pictures when you Tweet. Chris Bennett
data earlier economic enron investors life lock looking looks move next picture positive profits selling serious signs starting step tone toward year
The positive tone has more to do with the economic data that showed some signs of life in the economy. We've got through the Enron debacle and some selling that represented investors looking to lock in profits earlier on. Now we're starting to get a serious picture of what next year looks like, and it's probably the first serious step toward an upward move in the market. Joseph Battipaglia
data fortune fun hacking seeing shift theft
We are seeing a shift from the destruction of data to the theft of data. They are going from hacking for fun to hacking for fortune. Dean Turner
data economy saying starting tends
There are data saying that the economy is starting to recover, and there are data saying that it tends to be weak, William McDonough
data interface link management platform services single voice
We're integrating voice and data services on one platform -- with a single management interface and a single link to the Internet, Lewis Platt
data facts judgment
Making good judgments when one has complete data, facts, and knowledge is not leadership - it's bookkeeping Dee Hock
data used connected
Everybody is connected to everybody else, all data that can be shared will be shared: get used to it. Eben Moglen
data inquiring scientist
A scientist naturally and inevitably ... mulls over the data and guesses at a solution. He proceeds to testing of the guess by new data-predicting the consequences of the guess and then dispassionately inquiring whether or not the predictions are verified. Edwin Powell Hubble
data finals body
If the assumptions used in calculating energy are changed, then this seriously affects the final result, even though the same body of data might be used. Charles Francis Richter
expected further guards played positive since team
The positive was our team play was further ahead. I thought our guards played the way they should have. They played like I expected since they're the veterans. Jeff Mittie
expected
We're in a win-win situation. If we lose, we've still done more than we expected in our first year. Paul James
expected factory gates generation happier hated left life occurred walked work
Our grandparents' generation never expected too much out of life and, paradoxically, were happier for it. It never occurred to my granddad that he would enjoy work. He hated it from the day he walked through the factory gates at 14 to when he left at 65. Mark Barrowcliffe
expected good program strong
Wayland has a strong program so I expected this to be a good game. Kelly Trahon
expected koreans olympics skating time
When I was little, I had never really expected to win such a big competition. For a long time, just skating in the Olympics had been my goal because not many Koreans had done it. Kim Yuna
expected fallen great growth number sales taxes
We're doing great on growth on sales taxes so far. We expected this number to fall, but it hasn't fallen yet. Greg Albrecht
expected hard paid people team tried
We're a young team and not too many people expected much out of us. We tried to go out there and play hard every day and it paid off. Russell Robinson
expected poverty recession three trouble
Three years after a recession we're still having trouble getting into a recovery. I would have expected poverty to go down. Ron Haskins
expected
We know what's expected of us, and we know what we need to do. We don't want to end up like two years ago. Jeremy Mincey
gasoline planned
We've always planned on gasoline being over $65 a barrel, Jeff Bell
gas impact prices reasonable sustained tourism
We're not anticipating any sustained impact on tourism as long as gas prices come down to a reasonable level. Brad Dean
gas good knew tempo
We knew they would give us a good game. We just wanted to keep the tempo up. They had a lot of gas left. Sylvia Hatchell
gasoline hostile market prices small
We've never been in a market like this, where gasoline prices are cheap. It's a world that's very hostile to small cars. Maryann Keller
gas growth industry natural support
There are opinions, no way that our natural gas industry do not support the growth and development of industry at home. Industry Idris
gasoline-prices government car
The only way people are going to change their car buying habits, and the only way government will get behind alternatively fueled vehicles, is if gasoline prices continue to go up. Alexandra Paul
gas since
Since 9/11, we have been monitoring gas prices. Steve Carter
gas last
She is come at last - at last - and all is gas and gaiters! Charles Dickens
gas impossible mission total
Mission Impossible 3 was actually a total gas for me. It was really fun. Frank Darabont
held people supported war
The people who supported the war must be held accountable. Jonathan Tasini
held higher responsibility social standard
We have a social responsibility and we are held to a higher standard than other institutions, Jackie Robinson
held moving work
We have never held out or said that we are doing everything perfectly, and we have accomplished everything. We have said that there's more work to be done, but that we are moving forward. Dr. Fukino
held low market regard stocks
Fundamentally cheap stocks are often held in low regard by market participants. Something may be tainting their perception in investors' minds. Kenneth Fisher
held liked points taken
We would've liked to have taken those points and held on to them a little. Bill Kennedy
held meetings room sam since team time
We're in the room where Sam (Torrance) held all the team meetings in 2002, it's the first time I've been in here since then. Paul McGinley
held
I just feel like I have this gift that I've been given. It's like, 'Someone unwrap it! Here it is!' That drive can't be held down. Katy Perry
held kids sure
We want to make sure these kids aren't held up. Heidi Perlman
held publish
I think the next thing I publish will be for children, but I don't really want to be held to that because I also know what my next book for adults will be, and I really like that, too, so it depends. I've always had more than one thing going. J. K. Rowling
industrial looking property
We're about out of industrial property at the interstate. It's one of those things when you're looking for property, you need a lot. Allen Newton
industrial rubber
I think that an industrial process is not like a rubber stamp. Everything has to be put together and, as such, should have its own expression. Ludwig Mies van der Rohe
industrial relish
Listen, man: I am not the industrial godfather, king, whatever. I don't relish that title. I don't like it. I think it's limiting. I do country, I do blues. I don't just go straight. Al Jourgensen
industrial looking pittsburgh
The prospective is amazing. You really get the feel of looking down on this Pittsburgh industrial neighborhood. Brian Rogers
industrial product promise
There is a real promise for this product for the industrial market. John Coniglio
industrial
Basically, theater or film is a dangerous industrial environment. John Rhys-Davies
industrial time
I majored in industrial design/painting, but haven't had time to exercise that creativity. Elisabeth Hasselbeck
industrial lead research seek
must seek to take the lead in industrial and research innovation. Jacques Chirac
industrial lower tax
I think you need to lower your industrial tax rates. Steven Johnson
lessons shapes pay
Everything shapes you to be the person you are today. Sometimes hard lessons pay off dividends. Al Jourgensen
lessons matter facts
No matter what you do, you can never please everyone. And that was the hardest lesson to learn. In fact, I'm still learning it. Chris Colfer
lessons painful evolve
Unless you continually work, evolve, and innovate, you'll learn a quick and painful lesson from someone who has. Cael Sanderson
less looking toward
We are looking less favorably toward 2016 bidding at this moment, Peter Ueberroth
less mean point push start sure year
We are at the point of the year where if you push him back, it could mean one less start at the end of the year. We need to make sure that he can pitch. If we do push him back, we want to make sure we have the matchups we need at the end of the season. Mike Scioscia
lessons used teach
I used to teach dance lessons. Eartha Kitt
lessons rewards hell
The lesson is, the rewards in life don't always go to the biggest, or the bravest, or the smartest. The rewards go to the dogged; and when your going though hell, to the person who just keeps going. Bear Grylls
lessons-to-be-learned alive process
Success is a process that continues, not a status that you reach. If you are alive, there are lessons to be learned. Denis Waitley
lessons firsts given
To know ourselves, is agreed by all to be the most useful Learning; the first Lessons, therefore, given us ought to be on that Subject. Eliza Haywood
likely rockets solid violent whether
Whether solid rockets are more or less likely to fail than liquid-fuel rockets is debatable. More serious, though, is that when they do fail, it's usually violent and spectacular. Henry Spencer
likely puts september window
We're going to have to make some modifications to the tank, so that probably puts the September (launch) window into a not very likely possibility. William Gerstenmaier
likely understanding
We're more likely to be understanding than to be judgmental. David Carr
likely meaning ourselves setting tie
When our purpose is external, we may never find it. If we tie our purpose or meaning to our vocation, goal or an activity, we're more than likely setting ourselves up for suffering down the line. Kris Carr
likely volume
I'm working on something that's not yet novel-shaped but is something of a film-noir-flavored 'Alice in Wonderland.' It will also very likely be a single volume story and not the start of a series. Erin Morgenstern
likely normally problem
Least likely normally to have a problem is the kicker. Dick Vermeil
likely multiple parties
Settlement talks, if any, will likely be very complex, with multiple parties involved. Henry Blodget
likely problem
The overcrowding problem is likely to get worse. Keitaro Matsuda
likely overall remain sales somewhat total
The overall total of nominal sales is likely to remain somewhat weak. Anthony Chan
next generations products
The next generation product almost never comes from the previous generation. Al Ries
next causes steps
I love to just go to the movies, watch movies, listen to the scores and all that 'cause that's, like, the next step for me. Akon
next
We want to see who we're going to keep around next season. Mike Butters
next want knows
I don't want to go bald, I don't know what's coming up next. Chris Cooper
next performances improving
Everything I do is geared towards improving my next performance. Carolina Kluft
next performance sequels stock store
The performance of the stock is going to come down to the movies. It's that simple. And there are no sequels in store for next year. David Miller
next percent spending total
We are making a dent, but we are not going to be at 10 percent of total spending by next year. Greg Stuart
next night parking spent until
We spent the night at a parking lot until the next morning. David Foster
next faces realization
In the face of impermanence, if your next thought is good, this is what we call the realization body. Bill Porter
production
We're getting production from different people. They're working well as a team. Ed Miller
production recording step
The production and recording is a big step up. Grayson White
production
We are not getting the production offensively for what we need to be successful. Frank Robinson
production value videos youtube
The production value of YouTube videos is not there. Dana Brunetti
production
Hopefully, they'll be back in production very soon, Rick Perry
production
I wouldn't want to say how much production has been slowed, but it has been slowed. Definitely. Mark Klein
production step
When you get opportunities, you have to step up and take them. We need production from our bench. Dee Brown
production ramp resides technology
We must be able to ramp up production and migrate the technology to more models, but we can't do that if the know-how resides abroad. Phil Martens
production shooting
We are shooting for resuming the production in mid-September. H. Hart
retail worth
When this is finished, it will be a beautiful, pedestrian-friendly retail environment. It will have been worth it. Fred Delk
retail vibe work
When you work in retail long enough, you get a vibe off people. We all got that vibe off of him. Nancy Bray
retail
We're not going to have, post-9-11, at this location, retail uses. Richard Redniss
retailers
We're not going to do that. I think the retailers would go nuts. S. Walker
retail internet stores
Jeff Bezos is opening a retail store and owns a newspaper. Turns out everything we thought about the Internet is wrong. Aaron Levie
retail sales start year
Retail sales look to start off the year with a bang. Leslie Preston
retail seen softness
We have seen some softness in retail in October, Warren Jenson
retail side
This really spearheads them into the conventional retail side of the business, in a big way. Eric Larson
retailing terms
There is a bloodbath in retailing in terms of competition. Claudio Piron
round
You've got a little round ball and a little round bat and anything can happen. Lefty Grove
round
It wouldn't be fair to drag a child round the world, touring. Samantha Fox
rounds
I am a little surprised, but delighted, to be back in it and with two rounds to go anything is still possible, Catriona Matthew
rounds howls-moving-castle
Things are going round and round in my head--or maybe my head is going round and round in things. Diana Wynne Jones
rounds load products
I never went round to loads of managers saying 'this is what I have, this is my product and I'm going to be famous so you'd better sign me up.' They came to me. Amy Winehouse
rounds spoke washington
Laffey was in Washington making the rounds and I spoke with him then, Pat Toomey
round scale
If we scale back in Hong Kong, we should not scale back for the round as a whole. It is too important. Peter Mandelson
round season
This season will be his season. His all round game's a lot better and there's a lot more to come from him. Steven Gerrard
round state win
Overall, I'm happy. During the first round of the state tournament, you just want to get a win and get the jitters out. Cliff Thompson
sales special
When we have a special event, our sales triple, Peter Reynolds
salespeople resolve
Resolve to be among the top 20% of salespeople who make 80% of the sales. Brian Tracy
sales
Token sales have spiked, ... Token use has spiked. Jon Hanson
sales season stretch ticket
There has never been a three-week stretch of season ticket sales like this. Ever. Tom McMillan
sales stores turn
Our sales are expanding. We've had to turn down stores for milk. Linda Thomas
sales
Overall, sales have been good. Things have been going smooth. Keith Pearson
sales ticket
Ticket sales are very solid, to say the least. Chuck Morris
sales spring until
We really won't see the story until we get into the spring and see the spring sales activity. Richard Foreman
sales trends
All of the sales trends are reshuffling the industry. Kim Hill
sets
It all sets up for a lot of drama. Gregg Marshall
sets term using
I think the danger with using the term 'trilogy' is that it sets up particular expectations in the reader's mind. Alastair Reynolds
sets team
We always say our team is like a family. With so many sets of siblings, it just makes it more like a family. Brent Pohlonski
sets since
I've been fat since I was seven, and being fat sets you apart. Cass Elliot
sets setting smart tendency vocal
When Kyra sets it makes her a lot more vocal and involved. She has a tendency when she's not setting to become an island. Kyra's a really smart player. Amy Cooper
sets
It is astonishing what a lot of odd minutes one can catch during the day, if one really sets about it. Dinah Maria Mulock
sets
When the application sets are similar, there?s movement. Mark Polansky
sets
When stress sets in, and pressure, I focus. David Hallberg
sets settle standards
He sets the standards really high, especially at the quarterback position, and he isn't going to settle for anything less. Matt Hasselbeck