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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
asian collapse decline dollar east generate ought point ready sharp small turmoil
The possibility of a US dollar collapse or sharp decline may be small at this point but it would generate very significant turmoil so East Asian economies... ought to be ready for that. Masahiro Kawai
asian companies defining emerging forces joining leader listen people popular proud stars throughout watch whose
We are proud to be joining forces with the emerging leader of Asian popular culture, Korea, whose companies and stars are increasingly defining what people listen to, watch and play throughout the world. Travis Rutherford
asian concerns cut greater longer oil pressure
There are concerns that the longer $60 oil persists, the greater the pressure will come (on Asian governments) to cut subsidies. David Fyfe
asian persons ifs
Even if he is your friend, never, ever call an Asian person. Bo Burnham
asian beauty boxing compete course dominated heights imaginable job mount people punched southeast throughout triumph win won
We have scaled the heights of Mount Everest, dominated the Southeast Asian games, we have won international beauty titles, and of course punched our way to triumph in the boxing world. Our people compete and win every day in every imaginable job throughout the world. Gloria Macapagal-Arroyo
asian half increase last sector seeing seems since weak year
What we're seeing is an increase in the manufacturing sector, ... The manufacturing sector has been very weak for the last year and a half -- since the Asian (financial) crisis. Now, that sector seems to be recovering. Anthony Crescenzi
asian brings capacity courses deeper developing european gives language languages peace prosperity students understanding
World language courses are developing students in a capacity in European and Asian languages and this gives them a deeper understanding of not only language, but culture. It brings prosperity and peace to this world. Gaston Caperton
asian celtic common element factor music similar united
And it's very strange, but I think there is something very common - not only in Celtic music - but there is a factor or element in Celtic music that is similar in music that we find in Japan, the United States, Europe, and even China and other Asian countries. Nobuo Uematsu
asians blacks conversation flipped man race referendum reform whites
Why don't we hear more about and from Asians when it comes to race in America? Are Asians the new Invisible Man - there but not there? In some ways, yeah. Blacks and whites are always carping about the metrics of racism. And any conversation about immigration reform is immediately flipped into a referendum on Hispanics. John Ridley
dollars hiv cost
Pharmaceutical companies have invested hundreds of millions of dollars in new HIV/AIDS treatments not out of altruism but because they can make up those research costs in sales. David Mixner
dollars poor taxpayers
In business, poor performance leads to bankruptcy or, at a minimum, a restructuring of the company. In American education, failure entitles the bankrupt system to even more taxpayer dollars. Cal Thomas
dollars quarters billions
Anyone that makes me a quarter of a billion dollars, I like. Carl Icahn
dollar economy euro fall last limited looking potential rates saw support year zone
The potential for the euro to fall is pretty limited from here. The dollar is not going to get the same support we saw last year from rates now, and the euro zone economy is looking more solid. Tony Norfield
dollars exists interest pint rates sell sold spike upset value
The possibility exists that they would get upset with us at some pint and sell dollars. And if they sold all those dollars right away, the value of the dollar would plummet, interest rates would spike and the U.S. would go into a recession. Clyde Prestowitz
dollars millions raise work
You don't have to raise millions of dollars to be successful, you just have to work on something you are passionate about. Nick Woodman
dollars three roles
Economics played a role. Raleighs have gone from six fifty to nine dollars a carton, but there's a three-quarter cent coupon on the back. You can get all kinds of things with them, blenders, everything. I saved up enough one time and got Al Bumbry. Earl Weaver
dollars cost
Nothing that costs only a dollar is not worth having. Elizabeth Arden
dollars raw-materials plowing
He [Thomas Edison] considered [money] as a raw material, like metal, to be used rather than amassed, and so he kept plowing his funds into new projects. Several times he was all but bankrupt. But he refused to let dollar signs govern his actions. Charles Edison
enormous post respect
The Post has enormous respect for the Asian-American community. Howard Rubenstein
enormous given love
I was given an enormous amount of love by my parents. Liza Minnelli
enormous hesitation massively readers response
We have no hesitation at all in writing about those things. The readers are massively concerned. We get so many letters. We get massive, massive response to these issues, an enormous response. Peter Hill
enormous minor mistake steroids took
made an enormous mistake in my life: I took steroids while in the minor leagues. Michael Morse
enormous good people
I don't write about good and evil with this enormous dichotomy. I write about people. I write about people doing the kinds of things that people do. Octavia E. Butler
enormous equivalent freshman graduating high junior lose number points sophomore
We're graduating Gabe, and that's an enormous number of points to lose off a team, and we don't have his equivalent in junior high or in the freshman or sophomore classes. Gary Strickler
enormous face governor mentioned york
Let's face it. When you're the governor of New York and even mentioned as a presidential candidate, you're going to be under an enormous microscope. Norman Ornstein
enormous goes squeeze
You're an enormous sponge and everything goes in there and you squeeze it out in songs, I guess. And if you're a painter, you squeeze them out on to a canvas. Feist
enormous life progress share work
I've always had an enormous sense of independence. But I know that sometimes I can be too independent. It is important to be able to share your life - so that is a work in progress for me. Emilia Fox
exploiting ought outlets using
Media outlets that are exploiting Ebola because they want a sensational story and politicians using it to their own ends ought to be ashamed. Robert Reich
exploiting explore hacking network systems telephone type
Phone phreaking is a type of hacking that allows you to explore the telephone network by exploiting the phone systems and phone company employees. Kevin Mitnick
exploiting incidental irish late local merely poetic poetry pursue writers
Poetry is not Irish or any other nationality; and when writers such as Messrs. Clarke, Farren and the late F. R. Higgins pursue Irishness as a poetic end, they are merely exploiting incidental local colour. Patrick Kavanagh
exploiting opportunity wherever
Wherever they can find an opportunity, they are exploiting that opportunity to the fullest. Peter Martin
exploiting game middle running takes wide
They were exploiting us in the running game. The middle was wide open, so it was tough. But the running game takes all 11 guys. Mike Minter
exploiting growth high india nations oil prices producing rates totally
The spurt in world oil prices is totally unjustified as the oil producing nations are exploiting high growth rates in India and China. Alan Johnson
exploiting ways
Everybody's got the same goal. There are a lot of different ways of exploiting that, John Yost
exploiting felt guilt opportunity taking
I felt some guilt taking from Ruth. I'm exploiting the opportunity being a thief. I was disappointed when I was put on the floor. John Harrington
largely leadership
For many years, Myanmar's leadership was largely shut out from the world of international diplomacy. Najib Razak
largely model save
What Snapchat said was if we try to model conversations as they occur, they're largely ephemeral. We may try to write down and save the really special moments, but by and large, we just try to let everything go. We remember it, but we don't try to save it. Evan Spiegel
largely logistics
We are largely deferring utilization (of the station) and we are paring logistics (flights) to the bone. Michael Griffin
largely measures naturally people response truly work
When people are scared, they need something done that will make them feel safe, even if it doesn't truly make them safer. Politicians naturally want to do something in response to crisis, even if that something doesn't make any sense. But unfortunately for politicians, the security measures that work are largely invisible. Bruce Schneier
largely tells
What we're doing here is largely symbolic. But it tells everyone that we've got to help. We've got to do better. David Stern
largely time waged war
Grozny's been largely rebuilt. But at the same time, I think the war is very much being waged inside its survivors. Anthony Marra
largely life limited ours planned shelf society
We live in a disposable, 'cast-off and throw-away' society that has largely lost any real sense of permanence. Ours is a world of expiration dates, limited shelf life, and planned obsolescence. Nothing is absolute. Myles Munroe
largely positive stick
If you stick around long enough and you do enough of the right things, you get seen in a largely positive light. Brian O'Driscoll
largely
We also thought of ourselves in racial and largely ethnic terms. Samuel P. Huntington
legacy rich treats
It has been well observed that we should treat futurity as an aged friend from whom we expect a rich legacy. Charles Caleb Colton
legacy needs slavery
Part of the reason why we're only now reaching a point in American society where we can talk about the need for truth and reconciliation and the legacy of slavery is that it was such a dominant part of our history. Bryan Stevenson
legacy use
What do you do with your legacy, and how do you best put it to use? August Wilson
legacy dignity determined
Her legacy was her quiet dignity and instinctive rage against injustice, ... What she determined on the spot was that her dignity would not allow her to be treated unjustly. Diane Watson
legacy secure
making the world a more secure place for the irreplaceable legacy of the book. Terry Belanger
legacy protect feels
I do not feel I have a legacy to protect. Bret Easton Ellis
legacy
When I'm asked about legacy, I say it's too early to talk about legacy. Arlen Specter
legacy helping human-rights
A pardon for Edward Snowden would be good for America and would help burnish the president's legacy as one of the primary defenders of human rights. Anthony Romero
legacy rio run sports unclear
Rio will have to look after the legacy of infrastructure. But it's unclear who will run the sports centres after the Olympics. Eduardo Paes
makers money morning
She was one of the all-time money makers for the studio, ... She use to tell us in the morning she could get anything we needed. Jerry Maren
makers policy science scientists studying worried
Even before Sputnik, scientists and policy makers worried that not enough Americans were studying science. Virginia Postrel
makers lawmakers policy
I'm the policy-maker; I'm the lawmaker. Chuck Grassley
makers
For you are the makers of the flag and it is well that you glory in the making. Franklin Knight Lane
makers
The Maker is the one who is part of what he makes. Orson Scott Card
makers mothers nation shape women
Women are the makers of the home,the nation and the world. You are the mothers who shape the generation. Sathya Baba
makers true wish
We just wish the same kind of self-restraint could be true for the makers of brand-name drugs. John Rother
makers made manage
Nothing can be made except by makers, nothing can be managed except by managers. Money cannot make anything and money cannot manage anything. Henry Ford
makers policy serious
There will have to be policy makers in the room. These are serious discussions. Stephanie Rollings
offering flames wind
Without the Spirit of God we can do nothing. We are as ships without wind or chariots without steeds. Like branches without sap, we are withered. Like coals without fire, we are useless. As an offering without the sacrificial flame, we are unaccepted. Charles Spurgeon
offering errors judging
Save me from the error of judging a church by its size, popularity or the amount of its yearly offerings. Aiden Wilson Tozer
offering giving offering-to-god
We ought not to be looking for a place to hide, but a place to give ourselves as an offering to God. Aiden Wilson Tozer
offering care return
By offering individuals ownership and control of their health care coverage, we return control to the patients; and that is exactly where it should be. Chris Chocola
offering media ideas
Being overseas at the time it all kind of happened was perfect because I had no idea that it was going to attract so much media attention and provoke these lovely people calling in and offering up their opinions and advice. Cathy Freeman
offer plane private response sea tigers
We are awaiting a response from the Tigers to an offer of a private sea plane for their use. Palitha Kohona
offering tickets
We started by offering tickets to evacuees in the Starkville motels. We thought we would give out about 200 or so. Larry Templeton
offering yankees guy
One of the best things about being a Yankee is that you have guys like Whitey Ford, Phil Rizzuto, Ron Guidry and Reggie Jackson wandering around the locker room offering you advice. Derek Jeter
offering perfect culture
No place is perfect, but I admire Oahu for its offering of the tropical and the urban, and then its Asian-inflected culture and cuisines. Chang-Rae Lee