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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
ailments fever medicines minor people prescribe whenever
Shahid Sayed Akhtar used to prescribe medicines whenever we people got cold, fever and other minor ailments and therefore, he was nicknamed as 'doctor by us. Abdul Latif
ailments body dirty ensure environment food lead number prepare pure
One should always ensure a pure environment while making food. One should never prepare food with dirty hands. This could lead to a number of ailments and make the body weak. Rig Veda
ailments battling happen kidney skin towards year
Now we're getting towards the end of the year and we're battling some skin infections and kidney ailments that just happen to be part of the sport. Russ Hellickson
ailments bound common english-scientist hath himself liable
Lastly, he must remember that he himself hath no exemption from the common lot, but that he is bound by the same laws of mortality, and liable to the same ailments and afflictions with his fellows. Thomas Sydenham
ailments captive elephants lack reason space suffering
Lack of space is the reason for most of the ailments that captive elephants are suffering from. Carol Buckley
ailments body devoid hundred weakness
To live for hundred years it is important that the body is healthy, devoid of weakness and ailments Atharva Veda
ailments dressed everybody hopefully luxury nice physical region
We've got some physical ailments right now. Hopefully we'll get everybody back for region play. The 10 that were dressed and were able to go all contributed in a big way. That's a nice luxury to have. Bob Wilson
ailments employers looking medicines people rightfully worry
The American people are concerned, and rightfully so. Americans should never have to worry that their employers are looking at the medicines they take, or the ailments they've had. Bill Clinton
ailments ban cures entirely illness lost
cures for diseases, ailments and illness that may be lost should we entirely ban this technology. Jim Greenwood
class two people
Mr Jarndyce, and prevented his going any farther, when he had remarked that there were two classes of charitable people: one, the people who did a little and made a great deal of noise; the other, the people who did a great deal and made no noise at all. Charles Dickens
class words-of-wisdom success-of-others
The worst class of sum worked in the every-day world is cyphered by the diseased arithmeticians who are always in the rule of Subtraction as to the merits and successes of others, and never in Addition as to their own. Charles Dickens
class safety age
Though we are perpetually bragging of it [the middle class] as our safety, it is nothing but a poor fringe on the mantle of the upper class. Charles Dickens
class citizens degradation
The American elite is almost beyond redemption. . . . Moral relativism has set in so deeply that the gilded classes have become incapable of discerning right from wrong. Everything can be explained away, especially by journalists. Life is one great moral mush--sophistry washed down with Chardonnay. The ordinary citizens, thank goodness, still adhere to absolutes.... It is they who have saved the republic from creeping degradation while their 'betters' were derelict. Charles Dickens
class homicide one-thing
When one thing takes another away, what do we call that?” she asked my class. “Homicide!” I called out Chris Colfer
class two people
There are two distinctive classes of people today, those who have personal computers, and those who have several thousand extra dollars apiece. Dave Barry
class people behaviour
Whatever people may say, the fastidious formal manner of the upper classes is preferable to the slovenly easygoing behaviour of the common middle class. In moments of crisis, the former know how to act, the latter become uncouth brutes. Cesare Pavese
class black why-not
Why not exploit, enslave, or exterminate a class that everybody is taught to regard as inferior? Carter G. Woodson
class white benefits
I regard affirmative action as pernicious-a system that had wonderful ideals when it started but was almost immediately abused for the benefit of white middle-class women. Camille Paglia
democratic diplomatic
I've always been completely autocratic. I've never learned to be diplomatic or democratic. Alan Parker
democratic message sure venezuela witness
My message to France and Europe is that we will make sure Venezuela won't witness the rise of another Pinochet. And we will do it the democratic way. Nicolas Maduro
democratic drawings poetry side work
Prose, poetry, and drawings stand side by side in a very democratic way in my work. Gunter Grass
democratic snowstorms
Few things are as democratic as a snowstorm. Bernard Williams
democratic
You cannot use the democratic process for the procurement of excellence. Kevin McCloud
democratic major middle permanent propose public reduction suspect
A Democratic president should propose a major permanent tax reduction on the middle class and working class. I suspect most of the public would find this attractive. Robert Reich
democratic egyptians freedom groups helping human institute move mubarak national piece politics practices raids republican respect rights toward
The raids on Freedom House, the National Democratic Institute and International Republican Institute, the Adenauer Foundation, and other groups helping Egyptians move toward respect for democratic politics and human rights were of a piece with the practices of Hosni Mubarak - only bolder and more repressive. Elliott Abrams
democratic figure moves primary remains
She remains a controversial figure when she moves out from the Democratic primary sweepstakes. Lee Miringoff
democratic given involved lip major minorities party service terms vote
Minorities give their vote to the Democratic Party, and the Democratic Party has given them lip service in terms of being involved in the party and in being major players. Lynn Swann
destined
I was persuaded now that I was destined to lead a life on the Plains. Buffalo Bill
destined foster guarantee hope permanent population segment spent
When we foster an economy without hope, we guarantee that a segment of our population will be destined to know homelessness on a permanent basis, and not for the one night I voluntarily spent at a shelter. Jackie Speier
destined hard managers people
I always thought there were some people who were just destined to be disengaged in their jobs because that was their personality, and no matter how hard managers tried, there wasn't much they could do with some of those people. Tom Rath
destined destiny determined
Some are destined to succeed, some are determined to succeed. H. Tejomayananda
destined european gas ground information russian shows ukraine
We have information from the ground that shows Ukraine has started illegally siphoning off Russian gas destined for European consumers. Sergei Kupriyanov
destined girl growing harder incredibly knew nickname prove tells time work
I knew from the time I was a young girl that I was destined to be a writer. I'm incredibly stubborn. The more someone tells me I can't do something, the harder I work to prove them wrong. My father's nickname for me when I was growing up was 'Hardhead.' Lori Wilde
destined destiny drown man proverbs
If a man is destined to drown, he will drown even in a spoonful of water. Yiddish Proverbs
destined felt saw
I saw Roland Barthes's 'Mourning Diary' at a bookshop, and I felt it was like I was destined to see the book. I read it all in one go while I was in the shop. The book was mind-blowing. Go Ah-sung
destined monkey slippery trees
The day the monkey is destined to die, all the trees get slippery African Proverb
disabled list pitcher sometime starting
We have a starting pitcher on the disabled list right now and he will come off sometime this season. So competition, there's always competition. Clint Hurdle
disabled doth law man sin
Sin disabled man to keep God's law, but it doth not enfranchise or disoblige him that he need not keep it William Gurnall
disabled father husband
My father was a disabled veteran; my husband is also. Sue Allen
disabled either related week
From our standpoint, he hasn't been here all week so we had to put him on either suspended or disabled. It was non-football related so we put him on the disabled list. Danny Barrett
disabled ought
I don't think one ought to bring a clearly disabled child into the world. John Sulston
disabled late rule
I have a rule on my team. If you are late and not on the disabled list, you won't be on my team. Ozzie Guillen
disabled putting season work
I have been putting in my work here. I don't want to end the season on the disabled list. Jody Gerut
disabled gone job knew last love majors might role stayed whatever
I'd love to be here, in whatever role they think I can help. I knew when Gil got healthy, my job would change. If he hadn't gone on the disabled list, I might never have stayed in the majors the last month. Jeff Harris
disabled florida hard looks worked
Kaz must have worked hard in Florida (when he was on the disabled list) because he looks better to me in the field. Willie Randolph
fastball utilize
We want to see his command, we want him to utilize his pitches, ... We also want to see him use his two-seam fastball and sinkerball. Clint Hurdle
faster players ran team
The other team had a lot more Afro-American players than we did and they ran a lot faster than we did. Fisher DeBerry
fast kept
We started off fast and we kept it up. Ken Hitchcock
fast good
We started fast and did some good things early. O. J. Simpson
fast field happen
When you've got a 20-horse field and a fast pace, anything can happen out there. Bob Baffert
fastidious few
There is one thing that matters, to set a chime of words tinkling in the minds of a few fastidious people. Logan Pearsall Smith
faster downsizing ifs
Here's the thing, you just have to drive a lot faster, and if you don't get there, we're both fired. Bill Murray
fast good guys hold job moving players supposed today took
We have to have a different mind-set - that was established today in our meetings, ... I think our players took hold of it and did a good job of practicing. It was a pretty fast practice, guys moving around where they were supposed to go. Herman Edwards
fast hope intention loose means playing side time
We have no intention of playing fast and loose with this document, with the OAU process, ... We only hope that this time around the other side really means what it says. Meles Zenawi
likely rockets solid violent whether
Whether solid rockets are more or less likely to fail than liquid-fuel rockets is debatable. More serious, though, is that when they do fail, it's usually violent and spectacular. Henry Spencer
likely puts september window
We're going to have to make some modifications to the tank, so that probably puts the September (launch) window into a not very likely possibility. William Gerstenmaier
likely understanding
We're more likely to be understanding than to be judgmental. David Carr
likely meaning ourselves setting tie
When our purpose is external, we may never find it. If we tie our purpose or meaning to our vocation, goal or an activity, we're more than likely setting ourselves up for suffering down the line. Kris Carr
likely volume
I'm working on something that's not yet novel-shaped but is something of a film-noir-flavored 'Alice in Wonderland.' It will also very likely be a single volume story and not the start of a series. Erin Morgenstern
likely normally problem
Least likely normally to have a problem is the kicker. Dick Vermeil
likely multiple parties
Settlement talks, if any, will likely be very complex, with multiple parties involved. Henry Blodget
likely problem
The overcrowding problem is likely to get worse. Keitaro Matsuda
likely overall remain sales somewhat total
The overall total of nominal sales is likely to remain somewhat weak. Anthony Chan
meaningful jobs frustrated
I need to feel like the work I'm doing is not necessarily important, but meaningful, at least to me, because otherwise it just becomes a day job. It just becomes factory work and I get really frustrated. Alan Ball
meaningful self competition
Competition in its best form is a test of self. It has nothing to do with medals. The winner is the person who gets the most out of themselves. Al Oerter
meaningful impact counter-culture
I have not been part of an active counterculture movement, as it is not the approach that I have personally pursued to create a qualitatively beneficial and meaningful impact on society. Al Seckel
meaningful world human-life
The basic wisdom of Shambhala is that in this world, as it is, we can find a good and meaningful human life that will also serve others. That is our true richness. Chogyam Trungpa
meaningful today counting
What one thing can you start counting today that will actually be meaningful in your life? Chip Conley
meaningful destiny looks
You've got to say 'yes' to your destiny. Life's happening right now, look around you. There goes some life. Come on, Mamma, live! Dave Chappelle
meaningful fiction
Fiction is socially meaningful. David Guterson
meaningful jobs real
I always assumed that at some point I would have to quit making jokes, get a real job and do something meaningful and productive that would actually benefit society. Fortunately this never happened. Dave Barry
meaningful appreciation views
I can't try to convert anybody. It's not in me to do that. But my faith has given me such an appreciation of people and meaningful relationships, and a world view which I didn't have before. And although I will fail every day, it gives me something to aspire to. David Suchet
people may medical
It is astonishing how much more anxious people are to lengthen life than to improve it; and as misers often lose large sums of money in attempting to make more, so do hypochondriacs squander large sums of time in search of nostrums by which they vainly hope they may get more time to squander. Charles Caleb Colton
people solitude multitudes
A multitude of people and yet solitude. Charles Dickens
people governing whole
My faith in the people governing is, on the whole, infinitesimal; my faith in the people governed is, on the whole, illimitable. Charles Dickens
people words-of-wisdom selfishness
Others had been a little wild, which was not to be wondered at, and not very blamable; but, he had made a lamentation and uproar which it was dangerous for the people to hear, as there is always contagion in weakness and selfishness. Charles Dickens
people words-of-wisdom want
Mrs. Boffin and me, ma'am, are plain people, and we don't want to pretend to anything, nor yet to go round and round at anything because there's always a straight way to everything. Charles Dickens
people next cleanliness
Cleanliness is next to Godliness, and some people do the same by their religion. Charles Dickens
people scary alive
I have heard it said that as we keep our birthdays when we are alive, so the ghosts of dead people, who are not easy in their graves, keep the day they died upon. Charles Dickens
people enemy
Some people are nobody's enemies but their own Charles Dickens
people romance wonder-woman
Superman/Wonder Woman, people expected, I guess, a lot of romance, or maybe something that wasnt emotionally deep. Who knows? Charles Soule
someday maybe-someday
I don't make my living making records. Maybe someday I will. Dan Auerbach
someday dare trade
Someday we will dare to trade good for true Andrea Gibson
someday
Someday I'd love to do Shakespeare. Christine Taylor
someday ifs
But maybe if we are surrounded in beauty Someday we will become what we see Jewel
someday south
Someday maybe I'll go back and see what the Deep South is like. Fred Armisen
someday
Whatever thrills you, anything you love to do, just say - Someday, I will. Jimmy Buffett
someday lifetime selling
Maybe someday you can accuse somebody of being a poseur by selling out and playing blues music, but that's just not going to happen in my lifetime. John Mayer
someday dangerous code
Someday. That's a dangerous word. It's really just a code for 'never'. Tom Cruise
someday conversation
Someday, someday, but certainly not now, I'd like to learn how to have a conversation. Sherry Turkle
technology hands people
Technology is destructive only in the hands of people who do not realize that they are one and the same process as the universe. Alan Watts
technology civilization goal
...the materialism of modern civilization is paradoxically founded on a hatred of materiality, a goal-oriented desire to obliterate all natural limits through technology, imposing an abstract grid over nature. Alan Watts
technology fit lifestyle
The success of SYNC is another proof point that we are doing just that. We will continue to innovate and expand the capability of SYNC by integrating even more new technologies that fit our customers’ lifestyles. Alan Mulally
technology matter watches
It doesn't matter what the technology is - no one will watch a Peter Greenaway film anyway. Alan Parker
technology fields needs
The computing field is always in need of new cliches. Alan Perlis
technology thinking people
I think it is inevitable that people program poorly. Training will not substantially help matters. We have to learn to live with it. Alan Perlis
technology bird worms
In software systems it is often the early bird that makes the worm. Alan Perlis
technology two benefits
Technology is always a two-edged sword. It will bring in many benefits, but also many disasters. Alan Moore
technology amish kind
I'm remote from most technology to the point that I'm kind of Amish. Alan Moore