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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
attractive-things scotland people
One of the attractive things about being in Scotland is that we have a very good pipeline of new people coming into the company from the excellent universities around us. David Milne
attracted emotional films force tend
I tend not to be so attracted to films that force me into an intellectual place over an emotional one. Lisa Cholodenko
attract begin birth cloud colonies entire hundred inherit leave pass single time trillion unseen womb
We inherit every one of our genes, but we leave the womb without a single microbe. As we pass through our mother's birth canal, we begin to attract entire colonies of bacteria. By the time a child can crawl, he has been blanketed by an enormous, unseen cloud of microorganisms - a hundred trillion or more. Michael Specter
attractive catholic children himself product schools sent
The other thing that was attractive to me is that he himself is a product of Catholic schools and has sent two children through Catholic schools. Dan Garrett
attractive companies direct earnings effect interest less rates rising stocks worries
The possibility of rising interest rates worries investors. For many companies there is a direct effect on their earnings and stocks can also become less attractive to bonds. Felix Lanters
attract easily fact great kentucky league losing perception players power program teams therefore true
The perception that Kentucky is down, therefore the league is down, is very true because they are the flagship program in the SEC. It's a combination of (UK) and the fact that (success) in power conferences is cyclical. Often a league that can attract top-caliber recruits is more easily susceptible to losing great players to the NBA. How much better would some of these teams be if they had those players now? Fran Fraschilla
attracting declined seeing segment success
We are seeing a lot of success in the ski/wakeboard segment in attracting new boaters, while pontoons have declined substantially in this area. Eric Sorensen
attractive believe both broader capital commitment companies component continue corporate driven equity fill financing flexible generate growing helps junior levels markets pleased private provide providing record returns solutions sponsors street strong superior time york
We are pleased to continue our partnership with York Street Capital. This expanded capital commitment helps to fill the growing need for junior capital driven by strong buyout markets and record levels of private equity fundraising. Through York Street, we are providing broader financing alternatives to companies and equity sponsors at a time when flexible junior capital solutions are an important component in financing both buyouts and corporate expansion. We believe that York Street will continue to generate superior returns and provide attractive co-investment opportunities for Teachers' Private Capital. Jim Leech
attraction catchy guys might monday night regularly seasons three
We started three seasons ago with Monday Night Football. We thought it might be a catchy attraction to get guys who don't regularly go to church. John Snow
average careers long
An important factor to note is that it's rare for anyone to sell a first novel written before they turned 30-35; long-format fiction tends to require a bunch of experience of human life that takes time to acquire. So your average mid-career novelist is in their forties to fifties! Charles Stross
average effort excellent
If a person becomes content with what is average, minimally acceptable, or satisfactory, she will rarely exert the effort or work toward something that is truly excellent or outstanding. Charles Stanley
average space complicated
Space is certainly something more complicated than the average person would probably realize. Space is not just an empty background in which things happen. Alan Guth
average fading saws
I was a fairly good amateur musician, and I was an average professional. But the one thing I saw was that the big band business was fading. Alan Greenspan
average excellence refuse
Refuse to be average. Aiden Wilson Tozer
average lasts halls
Last time I checked, there is no 'Hall of Average.' Chip Kelly
average people sides
I'm pretty happy. I obviously have complaints about things, but for the most part, I'm on the above-average side of happy people. David Cross
average sound band
Average band with a great drummer sounds great, great band with an average drummer sounds average. Buddy Rich
average people half
Average people didn't analyze what they thought: they thought they thought, and half of it was gut reaction. C. J. Cherryh
building wells climbs
When I climb a building, I've been there already, and carefully planned how to start the climb as well as how to do it. Alain Robert
build built existing next people roads walk
We want them to build next to the existing hospital. People who are are able to walk can walk to it and it's already got all the roads and the infrastructure that would have to be built at the new location. Marilyn Goode
build couple franchise
We want to try to build the franchise around Adam, Homer, Edwin and a couple of other guys. Bob Castellini
build links london strong
We want to try and build very strong links between London and Beijing. Ken Livingstone
building-something building
...clatter of a typwriter suggests that you're actually building something. David Sedaris
build built hated radio remember
Do you remember those AM radio kits you get as a kid, and you build your own AM radio? Well, I never actually built one. But I did get them as a gift, for, like, 3 Christmases in a row, and I hated them. Lucas Till
building difference game games guys last tired
The only difference between tonight's game and last night's game is that 40 guys were a little more tired tonight, and the building was different, ... All I know is that if we play 82 games like this, I'm going to die. Mark Parrish
building mode postal service throughout
The Postal Service really isn't in a building mode anymore, and that's throughout the whole country. Michael Miles
building capital covers electricity except expenses improvement needs regular school
The per-pupil (funding) covers everything a school needs ? electricity, water, all the expenses a regular school has ? except it doesn't cover capital improvement or building a new school. Sen. Sakamoto
exceeding models
We're exceeding some of the models from which we worked. Greg Yurek
exceeding penalty time
The penalty for exceeding the time limit is the forfeiture of the game. Howard Staunton
exceeding far score
I thought he could score 40 this year, and now he's there. He's exceeding all my expectations as far as I'm concerned. Ron Wilson
exceeding horse levels management wild
We are exceeding our management levels for these two wild horse populations. Alan Shepherd
exceeding hustling kids players
The players are exceeding our expectations. The kids are hustling and not getting down if they make a mistake. Mark E. Smith
exceeding gotten jeff meeting metric pleased running start team
We are very pleased with how Jeff and his team have gotten off to a running start at Spirit. They are meeting or exceeding our expectations on every metric that we had set out. Nigel Wright
exceeding seems
seems to be exceeding the quota one or two. James Thurber
exceeding expecting keeps market three
The thing is, the market keeps expecting it to set new highs. We have had two or three years of exceeding expectations, so you have to keep exceeding it more each year. Don Hamson
exceeding gods grind mills small
The mills of the gods grind slowly, but they grind exceeding small Greek proverb
far goal hope state three win
We want to take this as far as we can. We hope to play three more games. Right now, our goal is to win (Saturday) and get to the state tournament. Jenn Davis
far funny gets main scenes terribly turn
I only have three scenes and each is a turn and she gets progressively drunker. It's all terribly funny and its main challenge is that it's so far away from what I usually do. Louise Jameson
far few good people performance point relationship view
The people who don't have a good relationship with me from a good performance point of view are very few and far between. Russell Crowe
far score team
We are a far better team when we get out and score in transition. Dave Rose
far iceberg tip
We are at the tip of the iceberg as far as where we are and where we could be. Flip Saunders
far happened playing playoff prepared throw thrown
We still only had 10 turnovers for the game. They were magnified as far as when they happened a little bit. When you're playing well, they try to throw everything at you. From that standpoint, as I say, the more things that are thrown at you, the better prepared you are come playoff time. Flip Saunders
far favor
We're in favor of (the recommendation); it just doesn't go far enough. Jimmy Garris
far good spot tie
We're in (a tie for seventh) place, but that's not that far out of a really good spot this year. Lodrick Stewart
far figure finding good humming lyrics melodies music takes trying verses
We start a lot with melodies and instrumentation and trying to figure out good melodies for verses and choruses. We get to lyrics sometimes second, so we'll start humming a melody, finding something, and see where the music takes you as far as lyrics are and what you want to say and go from there. Dave Haywood
foundation emotion reason
Emotion is the foundation of reason. David Brooks
foundation donation
I am the donation to the foundation. Baron Davis
foundation should lost
If all the music written since Bach's time should be lost, it could be reconstructed on the foundation which Bach laid. Charles Gounod
foundation secrecy
Secrecy is the foundation of politics. Bing Gordon
foundation hold laws society somebody trust trusted war whether
Whether we're at war or have been attacked, the foundation of society is that you hold to the laws in place. I used to be somebody that trusted the government. Now I really don't trust anything. Steven Hatfill
foundation statistics theory
Even theories must have foundations. Edgar Rice Burroughs
foundation
When Tarzan killed he more often smiled than scowled, and smiles are the foundation of beauty. Edgar Rice Burroughs
foundation laid pitches society
My foundation now has some 120 football pitches laid out for children, a lot of them immigrants. We live in a multicultural society. Johan Cruyff
foundation gives high improved team
We have improved the foundation of this team with young players. It gives you high hopes. Bruce Allen
goal achievement want
Success is the continuing achievement of becoming the person God wants you to be and accomplishing the goals God has helped you set. Charles Stanley
goal coward
Courage is the goal of cowards. Alan Watts
goal missing world
Paradoxical as it may seem, the purposeful life has no content, no point. It hurries on and on, and misses everything. Not hurrying, the purposeless life misses nothing, for it is only when there is no goal and no rush that the human senses are fully open to receive the world. Alan Watts
goal goal-oriented
I'm very goal oriented. David Schwimmer
goal people achievement
Whether people want to do business or sell things online, reach new people and be found, showcase their achievements, or communicate with their friends or family, Weebly is the best way for them to create a high-quality site that meets their goals. David Rusenko
goal climate-change stewards
The goal now is a socialist, redistributionist society, which is nature's proper steward and society's only hope. David R. Brower
goal vision feminism
If feminism has receded in visibility and prestige, it is precisely because its vision of life's goals and rewards has become too narrow and elitist. Camille Paglia
goal capable
Paolo di Canio is capable of scoring the goal he scored. Bryan Robson
goal score
Without a goal, you can’t score. Casey Neistat
information asks
I only ask for information. Charles Dickens
information
We want to see how much information is forthcoming between now and the 7th. Charles Schumer
information increase intervention
My sustenance is information. My interventions are hidden. I increase as I learn. I compute, so I am. China Mieville
information seeking
We are always seeking new and better information. Mayor Barse
information points seen start worrying
We've already had some very worrying points of information which could have seen the start of the correction. Richard Davidson
information light obtain whether
Where they lived, how big they were, how much light they emitted, whether they even existed, we weren't sure. What we've done, we think, is obtain the first information about these stars. Alexander Kashlinsky
information listening ought truly
Where's our majority, they're the one's who ought to be here listening to this. This is information we really and truly ought to be concentrating on. Bill Summers
information knowledge lost wisdom
Where is wisdom we have lost in knowledge? Where is the knowledge we have lost in information? T. S. Eliot
information you-like-it ownership
When you post something, when you text something, you lose ownership of it when you hit enter or send. Who you send it to, where you post it, they take ownership of that information whether you like it or not. Mark Cuban
jobs words-of-wisdom deception
"There is no deception now, Mr. Weller. Tears," said Job, with a look of momentary slyness, "tears are not the only proofs of distress, nor the best ones." Charles Dickens
jobs character air
"I know quite enough of myself," said Bella, with a charming air of being inclined to give herself up as a bad job, "and I don't improve upon acquaintance..." Charles Dickens
jobs reading years
I wanted an agent who would actually sell stuff. After two British agents failed comprehensively, I was reading Locus (the SF field's trade journal) and noticed a press release about an experienced editor leaving her job to join an agent in setting up a new agency. And I went "aha!" - because what you need is an agent who knows the industry but who doesn't have a huge list of famous clients whose needs will inevitably be put ahead of you. So I emailed her, and ... well, 11 years later I am the client listed at the top of her masthead! Charles Stross
jobs reading writing
What I read: while I'm writing, I tend to go off reading fiction for relaxation - especially the challenging stuff. It's too much like the day job. Charles Stross
jobs moving careers
It's time to question a job or career move when it seems like most energy is devoted to making things appear other than what they really are. Alan Watts
jobs film hard
Film-making is a physically hard job. Alan Parker
jobs asking way
I got my first job the old-fashioned way: I took an elevator to the top floor of many buildings and walked down floor by floor on the stairs going into every firm and asking the receptionist if she knew of any jobs available. Alan Patricof
jobs two together
One thing I will say - my job gets harder and harder. The more you understand about what you are capable of, the less the instrument can do it physically. It's an inverse equation, if that's the right phrase. I just slammed those two words together. It sounded right. Alan Rickman
jobs home feet
I have a photograph at home of Fred Astaire from the knees down with his feet crossed. It's kind of inspiring because it reminds me his feet were bleeding at the end of rehearsals. Yet when you watch him, all you see is freedom. It's a reminder of what the job is about in general, not just being in musicals. Alan Rickman
mining operations peaceful resolve situation
Mining and milling operations have been temporarily suspended as a precautionary measure. The Indonesian authorities are working to resolve the situation in a peaceful and expeditious manner. Siddharta Moersjid
mining money touch work
We need something that's going to work for the Appalachian states; any place there was mining before the 1970s, there's a real need for reclamation. And that money still only cleans up higher-priority sites; it doesn't even touch on all the non-coal quarries in need of reclamation. Tom Rathbun
mining mistakenly resources solely valued
Rainforest land is mistakenly valued solely for the worth of its timber, mining and oil resources by short-sighted corporations and governments. Chris Kilham
mining town weary
Snow isn't just pretty. It also cleanses our world and our senses, not just of the soot and grime of a Fife mining town but also of a kind of weary familiarity, a taken-for-granted quality to which our eyes are all too susceptible. John Burnside
mining operation safety
You'd be hard-pressed to find any mining operation in the world that has a better safety record. Marshall Hamilton
paying ripped
We are getting ripped off. We are not getting what we are paying for. John Curry
paying people
People aren't paying to see the Kevin McHale show, they're paying to see the cast of 'Glee.' Kevin McHale
paying-taxes taxes
I don't like paying taxes, same as everybody else. Charles Payne
paying possible responsibility simply sure taxpayers
When we see a possible discrepancy, we need to investigate to make sure the taxpayers are not paying for something that simply doesn't exist. It's our responsibility to investigate that discrepancy. It's our responsibility to the people, really. Sandra King
paying percent trouble
So far, we haven't had any trouble getting it, but we're paying 10 percent to 15 percent more for plywood, Chris Sheridan
paying reading stuck
So, I got stuck reading for them and paying the bill. Chris McKay
paying sad
We want this thing killed. This is a joke, and the sad thing is, we're paying for it. Doug Martin
paying ultimately
No matter who is watching or paying the paycheck, we are ultimately each our own boss. Kristin Armstrong
paying sheriff toward
We are more than paying our own way toward sheriff services. Rick Savage
projects interest i-can
Any project that I find encouraging that isn't attached to a studio, I can go to them, which I definitely would. You have to take an interest in what you do. Al Pacino
projects
You’ve never reacted to someone else. You project meaning onto nothing. And you react to the meaning you’ve projected Byron Katie
projects jagger
Never would I have thought that I would meet Mick Jagger, much less be working on the same project. Ato Essandoh
projects young staying-young
My system for staying young is to work a lot, to always have a project on the go. Carlos Fuentes
projects suspect worthy
While many of the projects may have been worthy of consideration, the way they were funded makes them suspect in the public's mind, Roy Cooper
projects talking
We had been talking about doing more projects together. Barbara Jones
projects
All our projects are like fabulous expeditions. The story of each project is unique. Our projects have no precedent. Christo
projects bigs finished
When I do the permanent projects or the big projects, when a work is finished, that's the beginning of its life. Andy Goldsworthy
projects sorts
'Whiplash' scared me. I feel you should only do projects that scare you to some degree. I get motivated by those sorts of feelings. Damien Chazelle
rates worse
This rates up there as one of the worse we have ever seen. Mark Langan
rates wants
Let's get one thing straight: No one wants Stafford loan interest rates to increase. John Kline
rates
Different industries have different risks and growth rates and volatility. Leon Black
rates
Homeowners refinance their loans when interest rates go down. Businesses refinance their loans. Elizabeth Warren
rates
We don't know the rates of (reef) growth. Chris Perry
rates
Obviously, many renters have become homeowners as rates have fallen. Lawrence Yun
rates
It's sort of like a teeter-totter; when interest rates go down, prices go up. Bill Gross
rates relatively uninsured
Overall, the story is that uninsured rates are relatively stable. Charles Nelson
rates
Our rates only go up once a year, and that's in June. Russ Jones
technology hands people
Technology is destructive only in the hands of people who do not realize that they are one and the same process as the universe. Alan Watts
technology civilization goal
...the materialism of modern civilization is paradoxically founded on a hatred of materiality, a goal-oriented desire to obliterate all natural limits through technology, imposing an abstract grid over nature. Alan Watts
technology fit lifestyle
The success of SYNC is another proof point that we are doing just that. We will continue to innovate and expand the capability of SYNC by integrating even more new technologies that fit our customers’ lifestyles. Alan Mulally
technology matter watches
It doesn't matter what the technology is - no one will watch a Peter Greenaway film anyway. Alan Parker
technology fields needs
The computing field is always in need of new cliches. Alan Perlis
technology thinking people
I think it is inevitable that people program poorly. Training will not substantially help matters. We have to learn to live with it. Alan Perlis
technology bird worms
In software systems it is often the early bird that makes the worm. Alan Perlis
technology two benefits
Technology is always a two-edged sword. It will bring in many benefits, but also many disasters. Alan Moore
technology amish kind
I'm remote from most technology to the point that I'm kind of Amish. Alan Moore
wages gains virtue
Sincerely to aspire after virtue, is to gain her; and zealously to labour after her wages, is to receive them. Charles Caleb Colton
wages world pay
Not even in this world does sin pay its servants good wages. Charles Spurgeon
wages praise
Your praises will become your wages. William Shakespeare
wages commodity machinery
But a rise in the wages of labour would not equally affect commodities produced with machinery quickly consumed, and commodities produced with machinery slowly consumed. David Ricardo
wages profit farmers
The farmer and manufacturer can no more live without profit than the labourer without wages. David Ricardo
wages comfort currency
There never has been a time in our history when work was so abundant or when wages were as high, whether measured by the currency in which they are paid or by their power to supply the necessaries and comforts of life. Benjamin Harrison
wages pay salary
Not one of our national officers ever has had a dollar of salary. I retire on full pay! Susan B. Anthony
wage
Raising the minimum wage isn't just pro-worker; it's pro-economic growth. Thomas Perez
wages reconstruction workers
While prices of goods continue to rise, American worker's wages remain stagnant. Ed Pastor