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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
agency government years
Every year the Federal Government wastes billions of dollars as a result of overpayments of government agencies, misuse of government credit cards, abuse of the Federal entitlement programs, and the mismanagement of the Federal bureaucracy. Chris Chocola
agency goal support
I support Planned Parenthood privately with my personal contribution, and that should be the goal of any such agency, to find private donations. Chris Christie
agency fishing voice
If I were not African, I wonder whether it would be clear to me that Africa is a place where the people do not need limp gifts of fish but sturdy fishing rods and fair access to the pond. I wonder whether I would realize that while African nations have a failure of leadership, they also have dynamic people with agency and voices. Chimamanda Ngozi Adichie
agency agent carry free seen
Unrestricted free agency is not a savior. I've never seen an unrestricted free agent carry a team. But it is a tool. Doug Risebrough
agency benefits burdens california charge cost count economic employment four highlight jobs last lost operate promoting record recruiting state understanding vote year
We started this vote record last year to highlight the legislators who show an understanding of the economic and employment benefits of manufacturing and the cost burdens manufacturers incur to operate in this state. With over 340,000 lost manufacturing jobs in California over the last four years and no state agency in charge of retaining, recruiting and promoting manufacturing, we count on the Legislature to make this state more competitive for manufacturers. Jack Stewart
agency mutual patriotic sustain union
Mutual forbearance and reciprocal concessions: thro' their agency the Union was established - the patriotic spirit from which they emanated will forever sustain it. Martin Van Buren
agency complaints fact federal good hope job needs painful responding speed
We always hope our federal bureaucracy is going to do a good job responding to the needs of Americans. The painful fact is, this is a bureaucratic process. Unfortunately, there are complaints all over the place out there about the speed with which the agency is dispensing with these claims. Chris Kennedy
agency needs time-on-earth
You are to do the choosing here and now during this exciting and wonderful time on earth. Moral agency, the freedom to choose, is certainly one of God's greatest gifts next to life itself. We have the honorable right to choose; therefore, we need to choose the right. This is not always easy. Dieter F. Uchtdorf
agency choices pay
You have agency, and you are free to choose. But there is actually no free agency. Agency has its price. You have to pay the consequences of your choices. Dieter F. Uchtdorf
american-educator companies continuity good maintain
So companies have to be very schizophrenic. On one hand, they have to maintain continuity of strategy. But they also have to be good at continuously improving. Michael Porter
american-educator
Strategy 101 is about choices: You can't be all things to all people. Michael Porter
american-educator european might power
Without the potato, the balance of European power might never have tilted north. Michael Pollan
american-educator began letter passionate people studio teach whom worked wrote
When it began I wrote this passionate letter to people I knew, studio members, of course, and other people with whom we have worked over the years and I said come and teach our students. James Lipton
american-educator people proceed simply
One should proceed with caution. We may simply not be wise enough to do some of the kinds of engineering things that people are talking about doing. Leon Kass
american-educator chairs child eating noise problems
When I was a little child I had problems with eating in the cafeteria. The chairs would be jerking in and out, and there was a noise overload. Temple Grandin
american-educator ceremony closing distant lands return run runners
When the run is over, there will be a closing ceremony and the runners will return to the many distant lands from which they came. Dennis Banks
american-educator
I would not be here now if I did not have anti-depressants. Temple Grandin
american-educator
If I did not have my work, I would not have any life. Temple Grandin
bit positive turn
We want to take a little bit of this frustration and turn it into some positive momentum. Michael Goodling
bit grass hanging love prefer republican street
My style is a little bit different than most conventional Republican Party chairmen. My style is more grass roots-oriented. I'm much more of a street guy. I love hanging out in boardrooms, but I prefer to be in neighborhoods and communities. Michael Steele
bit difference higher maybe providence somebody talented teams
The only difference between Providence and maybe somebody a little bit higher in the standings is the young kids. Providence is talented but they're young. Young teams make mistakes. Jim Calhoun
bit final finish luck potential programs spots strong three top
The potential is there and with a bit of luck we could finish in the top four. There are two or three programs that are traditionally strong and the final one or two spots are usually up for grabs. Paul Woods
bit economic economy economy-and-economics energy gracefully higher move potential prices risk
The potential for even higher energy prices is a risk to the economic outlook. The economy has digested the higher prices gracefully so far. But it can get a bit of indigestion if prices move higher. Mark Zandi
bit national people talent talented team tonight won
The people who were here tonight now have an idea of the talent you see at the NAIA National Tournament. This team is every bit as talented as what you see at the nationals. In fact, if this had been 20 years ago when the NAIA had 600 teams, this team could have won it. Pat Sullivan
bit building built deciding model people precedent spaceship structures
The people who built the first of these structures had no model to go by, no precedent to use in building a monument. It's a bit like deciding to build a functioning spaceship in your back yard, and succeeding. Winifred Creamer
bit chris forced open throw wide
We've always been a little bit wide open anyway, but with Chris out, it kind of forced us to throw more. Mike Hathaway
bits bob brian coming dylan hopefully lots sit song stuff together totally type
We've all got lots of different influences. We never sit down to write a song and say, 'This is going to be a Brian Eno type of song,' or 'This is a Bob Dylan song.' It's totally little bits of lots of different stuff that come together and hopefully it's something coming out of us that we're creating. Robbie Guertin
educate importance
We want to try to educate them to the importance of reuse. Carol Wotton
educate footwear high importance local proper schools students work
We also try to work with local high schools to educate the students about the importance of proper footwear and training. More importantly, we try to educate their parents. J. J. Johnson
educate focus people special student study turned
We have a special focus on disadvantaged communities. We've never turned a student away. If young people wanted to study and were enthusiastic enough, we'd find a way to educate them. David Gore
educated kids parents recommend scare trying videos
We recommend parents come with their kids because some of videos are graphic. We are not trying to scare the youngsters, we just want them to be more educated so they can make better choices. Jenna Berry
educate
If you educate women, family size tends to go down. Jane Goodall
educate efforts elect growing issues multiple obstacles people work
We're growing in our efforts and abilities to work on multiple issues at once. Ultimately, we will prevail, but there are a lot of obstacles in the way. We need to educate people and elect more fair-minded representatives. Dyana Mason
educate job students totally yes
Yes it is our job to educate students but we can't educate students that are not totally with us. Kit Pfieffer
educated living people stepping
We had no idea so many people would actually go out on a reef. People need to be educated that they're stepping on living creatures. Maria Brown
educate situation teachers
Let's do what's right for the kids. Let's put them in the right situation and the teachers in the right situation to educate them. Matt Gibson
efforts joint operation prayers soldiers successful
This successful operation could be attributed to the joint efforts of the soldiers with the participation of the American forces, and of course, with the prayers of everybody, Angelo Reyes
efforts poverty produce small wealth
Wealth is when small efforts produce big results. Poverty is when big efforts produce small results. David George
efforts either good happened next number stop wasted
We have to get that next goal. You either have to get a stop or get the next goal. It's happened a number of times. Good efforts have been wasted because of it. Ethan Moreau
efforts
We're making Herculean efforts to get into some of these areas. Steve Denney
efforts team
We're going to need team efforts and we need each other down the stretch. Allen Iverson
efforts focus people recovering three
We're going to focus our efforts on recovering as many people as we can and on removing debris, which will take at least two or three weeks, Rudi Giuliani
efforts offers people structure trying word
We're getting offers of help; we're getting word that people are trying to structure efforts for us. Edward Jackson
efforts invested since team
Since the acquisition of Eckerd, our American team has invested considerable efforts into its integration and operation, Jean Coutu
efforts focus good post shooter
She's a good shooter from the outside. We can't focus all of our efforts on the two post players. Brandy Corbett
frequently grown united
I find myself frequently introducing myself to someone, saying that, you know, I've grown up black and biracial in the United States. Natasha Trethewey
frequently goes hopefully learn mistakes year
We're going to make mistakes. That's just the way it is. Hopefully you learn from those mistakes and don't make them as frequently as the year goes on. Brian Moehler
frequently savior suffered
The Savior has suffered not just for our iniquities but also for the inequality, the unfairness, the pain, the anguish, and the emotional distresses that so frequently beset us. David A. Bednar
frequently great influenced italian life movies period rome
I like Italian movies. I was frequently there in the '60s, in Rome and the vicinity. It was a great period in life. I was very influenced by their stuff. Clint Eastwood
frequently instrument itself magnitude scale visitors
There is another common misapprehension that the magnitude scale is itself some kind of instrument or apparatus. Visitors will frequently ask to 'see the scale.' Charles Francis Richter
frequently government perception versus
Government frequently has a problem recognizing perception versus reality. Bill Owens
frequently smarter wisdom
I actually don't think that I'm that much smarter than anybody else. It's just that I frequently just seem to know what to do, and I think that's wisdom. Ben Carson
frequently
We don't know how frequently this kind of mutation can appear, Yoshihiro Kawaoka
frequently interest
I had no interest in steroids. I didn't need them, and I didn't want them. I never wanted them. From the get-go, I've frequently mouthed off about their negative impact on the game. Gary Sheffield
importance lifting
I began to learn the importance of lifting things up and looking underneath. Deb Caletti
importance recognize
We want to recognize the importance of our employees. Dave Johnston
importance
Character is better than ancestry, and personal conduct is of more importance than the highest. Thomas John Barnardo
importance introduction consequence
For, usually and fitly, the presence of an introduction is held to imply that there is something of consequence and importance to be introduced. Arthur Machen
importance resonates
I learned the importance of being confident. I think that at the end of the day, it's not so much about what you look like - it's really about the way that you feel. That resonates with people. Olivia Culpo
importance issue lose mail office rather seat sell sent vote week weigh willing
We are not delegates who are sent here to weigh our mail every day and then to vote accordingly. There are issue of transcendent importance that you have to be willing to lose your office over ... I'm willing to lose my seat any day in the week rather than sell out. Henry Hyde
importance recognize six
We recognize the importance of getting the six lanes built. Debbie Tower
importance learned
As a doctor, I've learned the importance and value of listening. Ami Bera
importance supreme
God is either of no importance, or of supreme importance. Abraham Joshua Heschel
might stairs lorry
Mr Lorry asks the witness questions: Ever been kicked? Might have been. Frequently? No. Ever kicked down stairs? Decidedly not; once received a kick at the top of a staircase, and fell down stairs of his own accord. Charles Dickens
might use disaster
But ah! disasters have their use; And life might e'en be too sunshiny... Charles Stuart Calverley
might god-bless bless
God blesses us so that we might bless others! Charles Stanley
might wells ifs
I thought, "Well if I'm gonna react might as well overreact! Alan Moore
might quiet
Dead … might not be quiet at all. Chris Bohjalian
might outcomes infinity
For every action, there's an infinity of outcomes. Countless trillions are possible, many milliards are likely, millions might be considered probable, several occur as possibilities to us as observers - and one comes true. China Mieville
might naked world
Alan Zweibel is the funniest writer in the world. He might be even funnier when he's naked, but I'm afraid to find out. Dave Barry
might tools ifs
If Mozart had power tools, there's no telling how great his music might have been. Dave Barry
might ruins bourgeoisie
The bourgeoisie might blast and ruin its own world before it leaves the stage of history. Buenaventura Durruti
people may medical
It is astonishing how much more anxious people are to lengthen life than to improve it; and as misers often lose large sums of money in attempting to make more, so do hypochondriacs squander large sums of time in search of nostrums by which they vainly hope they may get more time to squander. Charles Caleb Colton
people solitude multitudes
A multitude of people and yet solitude. Charles Dickens
people governing whole
My faith in the people governing is, on the whole, infinitesimal; my faith in the people governed is, on the whole, illimitable. Charles Dickens
people words-of-wisdom selfishness
Others had been a little wild, which was not to be wondered at, and not very blamable; but, he had made a lamentation and uproar which it was dangerous for the people to hear, as there is always contagion in weakness and selfishness. Charles Dickens
people words-of-wisdom want
Mrs. Boffin and me, ma'am, are plain people, and we don't want to pretend to anything, nor yet to go round and round at anything because there's always a straight way to everything. Charles Dickens
people next cleanliness
Cleanliness is next to Godliness, and some people do the same by their religion. Charles Dickens
people scary alive
I have heard it said that as we keep our birthdays when we are alive, so the ghosts of dead people, who are not easy in their graves, keep the day they died upon. Charles Dickens
people enemy
Some people are nobody's enemies but their own Charles Dickens
people romance wonder-woman
Superman/Wonder Woman, people expected, I guess, a lot of romance, or maybe something that wasnt emotionally deep. Who knows? Charles Soule
technology hands people
Technology is destructive only in the hands of people who do not realize that they are one and the same process as the universe. Alan Watts
technology civilization goal
...the materialism of modern civilization is paradoxically founded on a hatred of materiality, a goal-oriented desire to obliterate all natural limits through technology, imposing an abstract grid over nature. Alan Watts
technology fit lifestyle
The success of SYNC is another proof point that we are doing just that. We will continue to innovate and expand the capability of SYNC by integrating even more new technologies that fit our customers’ lifestyles. Alan Mulally
technology matter watches
It doesn't matter what the technology is - no one will watch a Peter Greenaway film anyway. Alan Parker
technology fields needs
The computing field is always in need of new cliches. Alan Perlis
technology thinking people
I think it is inevitable that people program poorly. Training will not substantially help matters. We have to learn to live with it. Alan Perlis
technology bird worms
In software systems it is often the early bird that makes the worm. Alan Perlis
technology two benefits
Technology is always a two-edged sword. It will bring in many benefits, but also many disasters. Alan Moore
technology amish kind
I'm remote from most technology to the point that I'm kind of Amish. Alan Moore