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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
amazing art bach connected found people proof religion
I found it amazing people can think that art must be connected to religion. Religion may give art themes, but there would still be art without religion. Bach is not proof that art exists. Michel Onfray
amazing life romantic sharing
I've always really been a romantic at heart, and I have always wanted kids, and I think the idea of sharing your life with the right person is amazing, actually. Monica Lewinsky
amazing ball conscious effort inside normally post worked
The post play was amazing tonight. We normally try to play from the inside out and we made a conscious effort to get the ball into the post. That really worked well for us tonight. Joshua Staley
amazing came native people personal stories talking threw
The people who came in told us such amazing stories of their personal journeys, how they got to Madison, that we just threw out the scripts. What these people are talking about in their native tongues are their own personal experiences. Michael Graf
amazing certainly emily
There are certainly contemporaries that I admire, like Emily Blunt. I think she is amazing. Rosamund Pike
amazing bringing cast crew debut dream experience fox incredibly job partners proud screen thrilled toronto
We're incredibly proud that 'Smoking' is our debut film and we're thrilled to be partners with Fox Searchlight. Jason, the cast and crew did an amazing job bringing the film to the screen and our experience at Toronto has been a dream come true. David Sacks
amazing both credit daytime drama incredible people sports training
I got amazing training both with Theatre Sports... back in Edmonton, Alberta - I can't give those people enough credit - and the daytime drama I did. Incredible training, both of them. Nathan Fillion
amazing cameras image incredible mindful scale whether
The IMAX cameras are big and heavy. And they're loud. So you have to be mindful of whether or not they're worth it; I'd say the image quality is incredible and the scale is amazing. Nina Jacobson
amazing believe last
I can't believe it. I'm speechless. It is amazing to see where I've come from the last two years. Libby Trickett
artificial certain cultivated face including keeps literary plant test writer
A writer must face up to the test of reality, including political reality, and that can't be done if he keeps his distance. A literary style cultivated like a hothouse plant may show a certain artificial purity, but it won't really be pure. Gunter Grass
artificial-intelligence knows know-how
Artificial intelligence is what we don't know how to do yet Alan Kay
artificial build die hearts life machines reasonable society
We've got a duty to die and get out of the way with all of our machines and artificial hearts and everything else like that and let the other society, our kids, build a reasonable life. Richard Lamm
artificial choose free life organic police society stability stable
Life isn't stable. Stability is unnatural. The only stable society is the police state. You can have a free society or you can have a stable society. You can't have both. Take your choice. As for me, I'll choose a free, organic society over a rigid, artificial society any day. Tom Robbins
artificial chinese creatures date designed placed primarily reflecting
Artificial creatures date back to the ancient Chinese and Greeks. Renaissance automata were designed primarily to entertain, reflecting the value placed on leisure. Ken Goldberg
artificial whereas
Synths are a very low level of artificial intelligence. Whereas you have a Stradivarius that will live for a thousand years. Thomas Bangalter
artificial environment good work
We always want to live in an environment where there's no artificial block to good work. Chiwetel Ejiofor
artificial integrity sports
A sport has its own built-in integrity - doesn't need an artificial one. Chris Crutcher
artificial time totally
I think there is a little magic in the fact that I'm so totally real but look so artificial at the same time. Dolly Parton
crave people stories work
I always crave to see more stories about and by people of color, particularly new work by young black writers. Katori Hall
crave days good steak
I listen to my body. Some days all I want is a good steak and others, I crave veggies and quinoa. Tracee Ellis Ross
crave everyday feeling filled growing life people struggled valid
I've struggled so much, growing up, with just feeling that my life is valid because it's not filled with these hyper-dramatic moments, and I think a lot of people of my generation feel that way. We're so inundated with hyper-drama that people crave everyday life. Ellar Coltrane
craves suppose work
I come from the theater, where the response to your work is immediate, and I suppose there's a part of me that still craves that. Bryan Cogman
crave loud love noise
I'm a loud person; I love noise and aggression. I crave contact. Shirley Manson
crave lift thee unto
Time, the avenger! unto thee I lift / My hands, and eyes, and heart, and crave of thee a gift. Lord Byron
craves food trying
Toxicity causes nutritional deprivation - and your body then craves more and more food, trying to get what it needs. Suzanne Somers
crave
When you're a child, you crave formal recognition; you crave ceremony, celebration, certification of proof. Kaui Hart Hemmings
crave expressive
I crave to be able to photograph the way a painter paints - in a loose, expressive way. Chris Jordan
digital exactly found great mark photograph technology
When we find a fossil, we mark it. Today, we've got great technology: we have GPS. We mark it with a GPS fix, and we also take a digital photograph of the specimen, so we could essentially put it back on the surface, exactly where we found it. Louise Leakey
digital chance welcome
There's no more film; now everything's digital. I welcome this. It's fantastic for me to have a new chance. Bernardo Bertolucci
digital early increase pace phone sales seen third
We have seen an increase in the pace of digital phone sales during the early part of the third quarter. Jim Shaw
digital group handle matter process specialist transition
We're in the process of transition as an industry, so there's still?a need for a specialist group to handle digital media. It's a matter of maturity. David Cohen
digital last magazines year
Magazines have not been distributing digital subscriptions for very long. The traction for digital magazines has come in the last year and a half. Christie Hefner
digital last magazines year
Magazines have not been distributing digital subscriptions for very long, ... The traction for digital magazines has come in the last year and a half. Christie Hefner
digital print coexist
Print and digital comics will always coexist. Brian K. Vaughan
digital cameras reminiscing
I like digital cameras, because they enable you to reminisce immediately. Demetri Martin
digital great published trying useful works
Wouldn't it be great if you could put all the published works online? The Internet Archive is trying to become useful as a modern-day digital library. Brewster Kahle
experience
It is far better to borrow experience than to buy it. Charles Caleb Colton
experience taste helpful
One has to taste an experience for oneself and find out if the thing is genuine or helpful. Then, before discarding something, one has to go further, so that one gets firsthand experience. Chogyam Trungpa
experience incredible powerful pushed scores stories wonderful work
It was a wonderful experience to work with Sylvia. She pushed me to be more powerful with my acting, and she told me scores of the most incredible stories I've ever heard. She is amazing. Lukas Haas
experience hope negative remind talk whenever
I hope that whenever my daughter has a negative experience, I'm there to talk about it and remind her how we feel when it's done to her so that she doesn't do it to others. Lorraine Toussaint
experience lived richest
The person who has lived the most is not the one who has lived the longest, but the one with the richest experiences Jean-Jacques Rousseau
experience
We've all had experience to this point, which has been good. Mike Cisco
experience loved side totally west
West Side Story. It's a totally new experience for me. I've always loved theater. Diana DeGarmo
experience fools start wise
We start as fools and become wise through experience African Proverb
experience mental playing talent top tremendous
When you've got talent from top to bottom, everybody's playing to count. It's a tremendous experience to play without that mental cushion. Dan Brooks
games two lawyer
Battledore and shuttlecock's a wery good game, vhen you an't the shuttlecock and two lawyers the battledores, in which case it gets too exciting to be pleasant. Charles Dickens
games words-of-wisdom delight
To bring deserving things down by setting undeserving things up is one of its perverted delights; and there is no playing fast and loose with the truth, in any game, without growing the worse for it. Charles Dickens
games planning designer
I'm not planning a kickstarter game. And I'm not really a game designer. Charles Stross
games play self
The Universe is the game of the self, which plays hide and seek forever and ever. Alan Watts
games fire giving
Substances like LSD, which give away a secret about the nature of the social game - the human game and what underlies it - are potentially dangerous, of course, like any good thing is. Electricity is dangerous, fire is dangerous, cars are dangerous, planes are dangerous, but not so dangerous as driving on the freeway. The only way to handle danger is to face it. If you start getting frightened of it, then you make it worse. Because you project onto it all kinds of bogeys and threats which don't exist in it at all. Alan Watts
games boards vendetta
They say that life's a game, & then they take the board away. Alan Moore
games goal able
You don't score 64 goals in 86 games at the highest level without being able to score goals. Alan Green
games gambling casinos
The point is that it looks like gambling because the language of the game is money. Al Alvarez
games gambling cards
Hold'em is a game of calculated aggression. If your cards are good enough for you to call a bet, they are good enough to raise with. Al Alvarez
intelligence intellectual useless
It is only the constant exertion and working of our sensitive, intellectual, moral, and physical machinery that keeps us from rusting, and so becoming useless. Charles Simmons
intelligence politics fool
I will keep where there is wit stirring, and leave the faction of fools. William Shakespeare
intelligence
There is no such thing as Intelligence; one has intelligence of this or that. One must have intelligence only for what one is doing. Edgar Degas
intelligence may courses
Of course not. After all, I may be wrong. Bertrand Russell
intelligence run
Let's just say that more intelligence is needed. You can't just run up and do this, you have to think about it. Billy Higgins
intelligence music women
In the music industry, intelligence in women is undervalued. Bat for Lashes
intelligence-services numbers together
We haven't really had the time yet to pore through all those records in Baghdad. We'll find ample evidence confirming the link, that is the connection if you will between al Qaida and the Iraqi intelligence services. They have worked together on a number of occasions. Dick Cheney
intelligence intelligence-and-intellectuals luck proverbs
You don't need intelligence to have luck, but you do need luck to have intelligence. Jewish Proverb
intelligence-gathering flaws sept-11
But it is equally incontrovertible that if our intelligence gathering process is seriously flawed, we had better find out and find out fast if we are to avoid another Sept. 11. Adam Schiff
intense credibility needed-someone
I needed someone really intense, but also somebody with a lot of theatrical credibility. Denis Leary
intense interest indispensable
Intense interest in any subject is indispensable if you're really going to excel in it. Charlie Munger
intensely
I found out that most programmers don't like to test their software as intensely as I do. Kent Beck
intensely processes
What happens is that with difficult processes on a film, they get very intensely compressed because a clock is ticking. Kenneth Branagh
intensely interested visitors
As a child, I would demand that visitors to our house tell me a story. I was intensely interested in everything - still am. Kerry Greenwood
intensely met people snob
I think I'm not always what I seem. Most people, when they get to know me, say, 'You know, when I first met you...' People initially think I'm a snob because I'm intensely private. Evangeline Lilly
intense match monday nice
We had a very intense match on Monday (in the Hanover-Horton Invitational) so it was kind of nice not to have that tonight. Vicky Groat
intense playing
She and her caddy take it to a very intense level. It's in her character. As much as I'd like to play the way she's playing right now, that's just not the way I'm wired. Wendy Ward
intense practices room
She is probably as intense in the room as you want. She practices right with them. Mike Kundick
media people world
We live in this world of tweeting, and social media, and anti-social media, and all the rest, so no matter what you say, there is going to be what people say is a firestorm. I don't know what a firestorm is. Al Michaels
media negative
The media loves negative spin. Chloe Sevigny
media paper levels
Today's beauty ideal, strictly enforced by the media, is a person with the same level of body fat as a paper clip. Dave Barry
media priorities focus
Here in the news media, our focus is on speed. When we get hold of some new and possibly inaccurate information, our highest priority is to get it to you, the public, before our competitors do. If the news media owned airlines, there would be a lot less concern about how many planes crashed, and a lot more concern about whose plane hit the ground first. Dave Barry
media literature brands
There are not that many new media brands you can say that about nowadays. David Talbot
media instrumental-music outlets
Instrumental music is increasingly marginalized and there's just no outlet, there's no venue for it, in terms of media. David Sanborn
media government regulation
In the U.K., the history of regulation, certainly regulation of the media, is one in which, time and again, successive governments lacked the 'bottle' to enforce the powers that were available to them. David Puttnam
media corporations west
At least in the West, politicians, corporations and media moguls can no longer take for granted their power to control the public discourse - and have it go unchallenged. David Puttnam
media places-to-go social-media
Nowadays, social media is the easiest place to go to find something. David Nail
performance stocks
The performance of dividend-paying stocks has more to do with the fundamentals in their industries. Linda Duessel
performance perplexing pleasing usual
The pleasing performance has been accompanied by the usual perplexing developments on the regulatory front, Martin Broughton
performance proud team
We are proud of the performance of our team in the first leg. Raymond Hack
performance strip
When you strip everything out, the performance is pretty much as expected. Anthony Chukumba
performances i-can can-do
I've realized that I can do performances. David Hockney
performances best-performance
How much we like ourselves governs our performance. Brian Tracy
performances best-performance
The best performances, are those that can be performed once. Brandon Sanderson
performance poor
Softbank's poor performance is especially weighing on sentiment. Katsuhiko Kodama
performance pulls stays
She stays cool. She pulls out the big performance on the big day. H. Hunt
physics physicist hard
Physics is much too hard for physicists. David Hilbert
physics geometry particles
What physics tells us is that everything comes down to geometry and the interactions of elementary particles. And things can happen only if these interactions are perfectly balanced. Antony Garrett Lisi
physics calculus university
Hard to be a physics major at Rice University if you have flunked calculus. Elizabeth Moon
physics unfolding witness
Without us here to witness, the universe is just pointless physics unfolding. Daniel H. Wilson
physics strings theory
String theory is 21 st century physics that fell accidentally into the 20th century. Edward Witten
physics fluid gravity
There's no evidence whatsoever that Darwin had anything useful to say or anything to say period about how life began or how the universe began or how gravity began or how physics began or fluid motion or how thermodynamics began. He had nothing to say about that whatsoever. Ben Stein
physics tomorrow
Tomorrow is going to be a big physics day. Michael White
physics quantum theory
If [quantum theory] is correct, it signifies the end of physics as a science. Albert Einstein
physics metaphysics
The more I learn of physics, the more I am drawn to metaphysics. Albert Einstein
realistic
Let us keep expectations at a realistic level. Erik Solheim
realistic vision
We set a realistic vision on the playoffs. Aaron Finch
realistic stop
A realistic view of humanity will stop the proliferation of impossible injunctions. Abdolkarim Soroush
realistic skeptical
I'm a pretty skeptical person, and I'm a realistic person. Evangeline Lilly
realistic release seriously spring thinking
No one is seriously thinking a spring release is realistic any more. Hiroshi Kamide
realistic
I don't think it's at all realistic for them to get the EIS done before they deploy in August. David Henkin
realistic where-you-are where-you-are-in-life
You have to be realistic about where you are in life and enjoy it. Clint Eastwood
realistic practicals
I'm very practical and realistic. Debby Ryan
realistic screens
Any time I'm on-screen it is realistic because I don't pull my punches or anything like that. Dwayne Johnson
ultimate
Then HBO was the pie in the sky. HBO is the absolute ultimate. Casey Neistat
ultimate
Actions, not words, are the ultimate results of leadership. Bill Owens
ultimately upheld
And we made decisions on each of those matters which were ultimately upheld by the courts. Lloyd Cutler
ultimate
Getting to Omaha, that's the ultimate goal. If I batted .100 and we made it there, then I would feel like I succeeded. Brad Chalk
ultimate-success going-the-extra-mile great-success
No one ever attains success by simply doing what is required of him. Charles Kendall Adams
ultimately
I've never covered the president in any way other than that he is ultimately responsible. Helen Thomas
ultimate
I say God is the ultimate. Donald Trump
ultimate
Brainpower is the ultimate leverage Donald Trump
ultimately
A rebellion is not a revolution. It may ultimately lead to that end. Bhagat Singh