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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
certain diffidence valour
Discretion has been termed the better part of valour, and it is more certain, that diffidence is the better part of knowledge. Charles Caleb Colton
certain one-thing
For whatever the future holds, one thing is certain... It just won't be the same. Alan Moore
certainty evidence deals
Science deals in evidence and uncertainty. Religion deals in certainty without evidence. David Milne
certain head movies
I think there's certain things that I know in my head that I enjoy: action movies. Lucas Till
certain filmmaker individual observed point rather
I feel like I've been observed as an individual more than a gay person, or as a filmmaker with a certain point of view rather than a lesbian filmmaker with a gay point of view. Lisa Cholodenko
certainty forms global humans life nuclear producing soon stand threat tinker verge vintage war
If there is anything more frightening than the threat of global nuclear war, it is the certainty that humans not only stand on the verge of producing new life forms but may soon be able to tinker with them as if they were vintage convertibles or bonsai trees. Michael Specter
certainly continued obviously president relationship white
I certainly know that this relationship could not have continued the way it did, when I was at the Pentagon and the president was obviously at the White House, without Betty. Monica Lewinsky
certainly chinese doctors filtered following four gotten government individual latest listed manual medical ordinary people perceive profession raid shows step until version
Until about four years ago, the Chinese medical profession was still following a version of the diagnostic manual that still listed homosexuality as an illness. That has also changed, but that may not have filtered down into how individual doctors or just ordinary people perceive it. Things have certainly gotten better, though, but this latest raid shows that the government can still step back, as well as forward. Scott Long
certainty clearly johnson objective offer potential providing superior today upside value
We are providing Guidant shareholders with certainty of completion, significant upside potential and substantially more value today than the Johnson & Johnson transaction. By any objective measure, our offer is clearly superior to Johnson & Johnson. Pete Nichols
cutting giving wealth
Those that will not permit their wealth to do any good for others. . . cut themselves off from the truest pleasure here and the highest happiness later. Charles Caleb Colton
cutting lions teeth
He that has cut the claws of the lion will not feel quite secure until he has also drawn his teeth. Charles Caleb Colton
cute time years
The excess of our youth are checks written against our age and they are payable with interest thirty years later. Charles Caleb Colton
cutting men turkeys
It's over, and can't be helped, and that's one consolation, as they always say in Turkey, when they cut the wrong man's head off. Charles Dickens
cutting garden weather
In fine weather the old gentelman is almost constantly in the garden; and when it is too wet to go into it, he will look out the window at it, by the hour together. He has always something to do there, and you will see him digging, and sweeping, and cutting, and planting, with manifest delight. Charles Dickens
cutting popularity minutes
I know God can cut it (popularity) off in a minute. Charles Stanley
cutting stones firsts
Habits, soft and pliant at first, are like some coral stones, which are easily cut when first quarried, but soon become hard as adamant. Charles Spurgeon
cutting scripture ifs
If you cut him, (John Bunyan) he'd bleed Scripture! Charles Spurgeon
cutting years bangs
Billions of years ago you were a big bang. But now you're a complicated human being. And then we cut ourselves off. And don't feel that we're still the big bang. But you are. Alan Watts
dementia none reminded wants
None of us wants to be reminded that dementia is random, relentless, and frighteningly common. Laurie Graham
dementia details knew life remember somehow
At 93, so deep in dementia that she didn't remember any details of her life, my mother somehow still knew songs. Floyd Skloot
dementia
Dementia was like a truth serum. Amy Tan
dementia exercise extremely ready results
We're not ready to write an exercise prescription for Alzheimer's or dementia yet. But the results are extremely exciting. Carl Cotman
dementia
Let's not let our fear of dementia deepen our fear of dementia. Bill Crawford
dementia girl powerful russian serve
Do you know that Russian girl Dementia or something like that? Her serve is no more powerful than mine. Elena Dementieva
dementia early elderly large likely mimic number people taking
A large number of elderly people are taking medications that can mimic early dementia and are likely to be classed as having early dementia. Karen Ritchie
gone certain rings
To boldly go where no uploaded metahuman colony has gone before' has a certain ring to it, doesn't it? Charles Stross
gone
Your spikes have gone floppy, Darren Shan
gone tweet pretending
I've never gone on Facebook and am not sure I understand it. The same goes for Twitter. I have someone sending tweets and pretending to be me, but I don't know why. David Sedaris
gone towns big-families
It's a new town. The old elegance is gone. It used to be one big family, this industry. Cesar Romero
gone path reputation
Why sully the country's reputation when they've gone down this path only to back off at the end? James Fenkner
gone philosophy poet poets saturday sleeping window
Where is Philosophy sleeping this saturday afternoon? Are the philosophers already dead? Are the poets gone from the planet? I look through the window and all I see are advertisments. Mariana Fulger
gone teammates ups
When you've been teammates that long, you're going to go through some ups and downs. They've gone through some down times. Tim Purpura
gone thank
Thank Heaven, the sun has gone in, and I don't have to go out and enjoy it. Logan Pearsall Smith
gone feels left
I feel it gone, yet know not when it left. William Shakespeare
lasts remember there-is-hope
Remember, to the last, that while there is life there is hope. Charles Dickens
lasts fool firsts
Ridicule is the first and last argument of a fool. Charles Simmons
lasts dubbing spokes
I have just returned from the dubbing studio where I spoke into a microphone as Severus Snape for absolutely the last time. Alan Rickman
last nine won
We've won nine of the last 11, so I like our chances. Eric DiBiase
last people ready year
We want to show that we're no joke. People thought last year was a fluke. We can make improvements from last year. We're ready to see what's out there. Andrew Palmer
lasts eloquent last-time
We looked at each other for the last time; nothing is as eloquent as nothing. David Mitchell
lasts records haircuts
You're only as good as your last record. David Sanborn
lasts female worship
The last western society to worship female powers was Minoan Crete. And significantly, that fell and did not rise again. Camille Paglia
lasts needs kind
I need some kind of... like... last minute, poorly-set-up deus ex machina!! Bryan Lee O'Malley
people may medical
It is astonishing how much more anxious people are to lengthen life than to improve it; and as misers often lose large sums of money in attempting to make more, so do hypochondriacs squander large sums of time in search of nostrums by which they vainly hope they may get more time to squander. Charles Caleb Colton
people solitude multitudes
A multitude of people and yet solitude. Charles Dickens
people governing whole
My faith in the people governing is, on the whole, infinitesimal; my faith in the people governed is, on the whole, illimitable. Charles Dickens
people words-of-wisdom selfishness
Others had been a little wild, which was not to be wondered at, and not very blamable; but, he had made a lamentation and uproar which it was dangerous for the people to hear, as there is always contagion in weakness and selfishness. Charles Dickens
people words-of-wisdom want
Mrs. Boffin and me, ma'am, are plain people, and we don't want to pretend to anything, nor yet to go round and round at anything because there's always a straight way to everything. Charles Dickens
people next cleanliness
Cleanliness is next to Godliness, and some people do the same by their religion. Charles Dickens
people scary alive
I have heard it said that as we keep our birthdays when we are alive, so the ghosts of dead people, who are not easy in their graves, keep the day they died upon. Charles Dickens
people enemy
Some people are nobody's enemies but their own Charles Dickens
people romance wonder-woman
Superman/Wonder Woman, people expected, I guess, a lot of romance, or maybe something that wasnt emotionally deep. Who knows? Charles Soule
seeing selling
We are seeing a lot of selling for euros. Brian Martin
seeing slowing sort
We're sort of seeing an orchestrated slowing of the economy. But what we're not seeing is a slamming on the brakes. Bob Schnorbus
seeing start
We're going to start seeing a lot more of these. Tom Warner
seeing signs
What we're seeing now is the first signs of stress. Ed Stansfield
seeing
You're basically the sum of all the experiences you've ever had, and they're sort of shaken up in you and reproduced in the things you create, and that includes seeing movies. Ben Affleck
seeing
Seeing through is rarely seeing into. Elizabeth Bibesco
seeing throw trial
I think a lot of what you do in acting, and for the most part singing and dancing and everything, is trial and error. It's all about just seeing what works, and if it does, to use it, and if not, to throw it away. Nick Jonas
seeing
We are just seeing more and more of it. Dan Grunfeld
seeing
We are seeing some cases. It could be life-threatening. Von Roebuck
sound singers ifs
If you're a good singer, you're going to make anything sound good. Casey Abrams
soundtracks
I have music in my head constantly. I have to have a soundtrack in my head. Bob Mould
sound shows audience
I'm terrified of improv. Improv in a show or in front of an audience sounds terrifying. Elizabeth Olsen
sound rebound surface
Drums all have their own particulars - each drum has a place where they sound the best - where they ring out and resonate the best, and the head surface isn't too loose or too tight, mainly so you get a good rebound off of the head. Chad Smith
sound sometimes opinionated
I'm very opinionated and I have a lot of things to say. Sometimes I sound a bit like a willy. Cher Lloyd
sound
My God! What has sound got to do with music? Charles Ives
sound findings looking-for-work
Looking for work sounds almost as bad as finding it. Bob Black
sound life-experience
Sound comes out of a life experience. Bill Laswell
sound aviation corny
Let's get one thing straight: there's no such thing as the Bristol sound. Beth Gibbons
time son boys
A boy's story is the best that is ever told. Charles Dickens
time fool calendars
Tomorrow! It is a period nowhere to be found in all the registers of time, unless, perchance, in the fool's calendar. Charles Caleb Colton
time all-things
Time is the measurer of all things, but is itself immeasurable, and the grand discloser of all things, but is itself undisclosed. Charles Caleb Colton
time retreat tides
Time ... advances like the slowest tide, but retreats like the swiftest torrent. Charles Caleb Colton
time two black
Time,- that black and narrow isthmus between two eternities. Charles Caleb Colton
time looks one-thing
To look back to antiquity is one thing, to go back to it is another. Charles Caleb Colton
time world overcoming
Time is the most subtle yet the most insatiable of depredators, and by appearing to take nothing is permitted to take all; nor can it be satisfied until it has stolen the world from us, and us from the world. It constantly flies, yet overcomes all things by flight; and although it is the present ally, it will be the future conqueror of death. Charles Caleb Colton
time journey men
Much may be done in those little shreds and patches of time which every day produces, and which most men throw away. Charles Caleb Colton
time opportunity enemy
Time, the cradle of hope.... Wisdom walks before it, opportunity with it, and repentance behind it: he that has made it his friend will have little to fear from his enemies, but he that has made it his enemy will have little to hope from his friends. Charles Caleb Colton
weight looks lost
I'm constantly looking to see whether I look the same as I did earlier, whether I've put on or lost any weight. Chiwetel Ejiofor
weight body lines
This is a business meal. The calories do not count. I am mentally labeling these as 'business calories' so my body will know they were eaten in the line of duty and will process them differently. Cathy Guisewite
weight size
Wake me up when I'm a size 5. Cathy Guisewite
weight mouths way
The best way to lose weight is to close your mouth - something very difficult for a politician. Or watch your food - just watch it, don't eat it. Ed Koch
weight matter reason
In the matter of faith, we have the added weight of hope to that of reason in the convictions which we sustain relating to a future state. Edwin Hubbel Chapin
weight opinion third-person
Opinions only carry weight in the second or third person. Cass McCombs
weight able pressure
I don't feel any pressure to lose weight - and in any case, if I didn't have my food I'd be a nasty piece of work and wouldn't be able to function. Cat Deeley
weight plus unthinkable
My weight fluctuated when I was 30, and I did the unthinkable - I stepped out as a plus-sized model. Carre Otis
weight-lifting drink protein
I drink a lot of protein shakes and do a lot of weight lifting. Chanel Iman