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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
call clear information resources
We want them to have clear information about this subject, and resources to call on. Fred Engh
call effort takes
We want them to call us. It takes a collaborative effort with our partners. Steve McDonald
calling answers levels
The honest answer is more complex. On some level I was sent. Or inspired. Or called. But my calling, such as it was, wasn't a single booming invitation from above (really, is it ever?)... Chris Bohjalian
calling uncomfortable okay
I felt uncomfortable calling myself a writer until I started with 'The New Yorker,' and then I was like, 'Okay, now you can call yourself that. David Sedaris
call number
'Crush' was my first number one on the call sheet. Lucas Till
calling course developed files members prior release sealed
There have been a couple of instances prior to now where members of the House have filed resolutions calling for release of the sealed files which were developed during the course of our committee's investigation. Louis Stokes
call domestic interested whatever
I think I'm interested in these kinds of character dramas, psychological dramas, domestic dramas, whatever you want to call them - comedy dramas. Lisa Cholodenko
calling came consider education later life theater
Film is something that came later into my life. I had a Jesuit education, and I consider acting and the theater as kind of a calling - a vocation. Michael Moriarty
calling reason categories
I see no reason for calling my work poetry except that there is no other category in which to put it. Marianne Moore
careers chinese connected
I had always thought that I would do something that was connected to music as a career, or possibly Chinese, which was my major. Charles Soule
care safe danger
The Providence of God is the great protector of our life and usefulness, and under the divine care we are perfectly safe from danger. Charles Spurgeon
careers might brilliant
Those of you who are not aware of my brilliant career as a stand up comic, I'm not aware of it either so we might well wonder what we're doing here. Alan Rickman
careers long way
In many ways, my entire graphic novel career was a long diversion. Originally, all I wanted to do was to be an underground cartoonist and maybe bring out a groovy underground mag. Alan Moore
careers long people
During a long career in TV broadcasting, I spent a lot of time contributing to other people's creations. Alan Bradley
careers vision acting
Forget the career, do the work. If you feel what you are doing is on line and you're going someplace and you have a vision and you stay with it, eventually things will happen. Al Pacino
careers laughing three
Al and Tommy and I sharing the biggest laugh because it was predicted by everything we did in the first three or four records in my career. It was predicted in the grooves that we would be here sometime later on down the road. Al Jarreau
care may god-knows
Whatever may befall us, God knows and cares as no one else can. Aiden Wilson Tozer
career choose exposure females
We want them to have exposure to females who have a career and a family. We want to let them know that you don't have to choose one or the other. Linda Gray
dressed explain ghost holy island nine saw teacher
I can't explain something I saw on holiday on Holy Island when I was about nine years old, but do you know what, it could have been my PE teacher dressed in a monk's habit. I have no idea. I'm not a ghost person... it doesn't mean there aren't unexplained things; I just don't think they're ghosts. Tom Goodman-Hill
dressed home morning sure tip top works
As someone who works from home, my top style tip is to make sure you get dressed in the morning. Kate Reardon
dressed looks opportunity overalls people recognize
Most people don't recognize opportunity when it comes, because it's usually dressed in overalls and looks a lot like work. Thomas A. Edison
dressed lived
She was probably dressed that way during most of the first 10 years she lived here. Susan Mays
dressed latest newest people secret society tech themselves trend
It's no secret that in our society, and many before, people are trend followers. For some reason, they feel better about themselves if they are dressed in the latest fashion or have the newest tech gadget. Victoria Osteen
dressed family theme tin
One year, my family and I dressed up in the theme of 'Wizard of Oz' for Halloween. We all went as the different characters. I was the Tin Man! Luke Benward
dressed
You look phenomenal. You dressed the part. ... Your vocals were impeccable. Paula Abdul
dressed last life whip worth
Everyone should have hair. When you get dressed up, you must do that last whip of hair spray, or life's not worth living. Charles Nelson Reilly
dressed guy ran
You didn't have what we see today. There wasn't some guy out there dressed up like a farmer. No one ran around in a suit. Bob Parsons
life strong truth
There is nothing so strong or safe in an emergency of life as the simple truth. Charles Dickens
life saying-goodbye expectations
Life is made of ever so many partings welded together. Charles Dickens
life autism world
This is a world of action, and not moping and droning in. Charles Dickens
life moral existence
Let us be moral. Let us contemplate existence. Charles Dickens
life littles
Do all the good you can and make as little fuss about it as possible. Charles Dickens
life people astonishing
It is astonishing how much more people are interested in lengthening life than improving it. Charles Caleb Colton
life soul prison
Life is the jailer of the soul in this filthy prison, and its only deliverer is death. Charles Caleb Colton
life happiness dark
Much too oft we make life gloomy-- When happy we might be, If we gathered more of sunshine, And not dark shadows see. Charles Caleb Colton
life distance journey
Evils in the journey of life are like the hills which alarm travelers upon their road; they both appear great at a distance, but when we approach them we find that they are far less insurmountable than we had conceived. Charles Caleb Colton
love lost-youth ideas
I don't remember who was there, except Dora. I have not the least idea what we had for dinner, besides Dora. My impression is, that I dined off Dora, entirely, and sent away half-a-dozen plates untouched. I sat next to her. I talked to her. She had the most delightful little voice, the gayest little laugh, the pleasantest and most fascinating little ways, that ever led a lost youth into hopeless slavery. She was rather diminutive altogether. So much the more precious, I thought. Charles Dickens
love mind unhappy
There can be no disparity in marriage like unsuitability of mind and purpose. Charles Dickens
love friendship relationship
Never close your lips to those whom you have already opened your heart. Charles Dickens
love powerful disappointment
Mystery and disappointment are not absolutely indispensable to the growth of love, but they are, very often, its powerful auxiliaries. Charles Dickens
love honesty heart
To conceal anything from those to whom I am attached, is not in my nature. I can never close my lips where I have opened my heart. Charles Dickens
love mean men
You know what I am going to say. I love you. What other men may mean when they use that expression, I cannot tell. What I mean is that I am under the influence of some tremendous attraction which I have resisted in vain, and which overmasters me. You could draw me to fire, you could draw me to water, you could draw me to the gallows, you could draw me to any death, you could draw me to anything I have most avoided, you could draw me to any exposure and disgrace. This and the confusion of my thoughts, so that I am fit for nothing, is what I mean by your being the ruin of me. Charles Dickens
love lying men
What lawsuits grow out of the graves of rich men, every day; sowing perjury, hatred, and lies among near kindred, where there should be nothing but love! Charles Dickens
love night reality
I loved you madly; in the distasteful work of the day, in the wakeful misery of the night, girded by sordid realities, or wandering through Paradises and Hells of visions into which I rushed, carrying your image in my arms, I loved you madly. Charles Dickens
love christmas education
I will honor Christmas in my heart, and try to keep it all the year. Charles Dickens
men
Poetry's unnat'ral; no man ever talked poetry 'cept a beadle on boxin' day. Charles Dickens
men hair doors
An observer of men who finds himself steadily repelled by some apparently trifling thing in a stranger is right to give it great weight. It may be the clue to the whole mystery. A hair or two will show where a lion is hidden. A very little key will open a very heavy door. Charles Dickens
men brotherhood common
The more man knows of man, the better for the common brotherhood among men. Charles Dickens
men fellow-man spirit
It is required of every man," the ghost returned, "that the spirit within him should walk abroad among his fellow-men, and travel far and wide; and, if that spirit goes not forth in life, it is condemned to do so after death. Charles Dickens
men laughing people
When a man bleeds inwardly, it is a dangerous thing for himself; but when he laughs inwardly, it bodes no good to other people. Charles Dickens
men judging world
Most men unconsciously judge the world from themselves, and it will be very generally found that those who sneer habitually at human nature, and affect to despise it, are among its worst and least pleasant samples. Charles Dickens
men coats shabby
It is not every man that can afford to wear a shabby coat. Charles Caleb Colton
men talking two
When we are in the company of sensible men, we ought to be doubly cautious of talking too much, lest we lose two good things, their good opinion and our own improvement; for what we have to say we know, but what they have to say we know not. Charles Caleb Colton
men years two
No man can promise himself even fifty years of life, but any man may, if he please, live in the proportion of fifty years in forty-let him rise early, that he may have the day before him, and let him make the most of the day, by determining to expend it on two sorts of acquaintance only-those by whom something may be got, and those from whom something maybe learned. Charles Caleb Colton
people may medical
It is astonishing how much more anxious people are to lengthen life than to improve it; and as misers often lose large sums of money in attempting to make more, so do hypochondriacs squander large sums of time in search of nostrums by which they vainly hope they may get more time to squander. Charles Caleb Colton
people solitude multitudes
A multitude of people and yet solitude. Charles Dickens
people governing whole
My faith in the people governing is, on the whole, infinitesimal; my faith in the people governed is, on the whole, illimitable. Charles Dickens
people words-of-wisdom selfishness
Others had been a little wild, which was not to be wondered at, and not very blamable; but, he had made a lamentation and uproar which it was dangerous for the people to hear, as there is always contagion in weakness and selfishness. Charles Dickens
people words-of-wisdom want
Mrs. Boffin and me, ma'am, are plain people, and we don't want to pretend to anything, nor yet to go round and round at anything because there's always a straight way to everything. Charles Dickens
people next cleanliness
Cleanliness is next to Godliness, and some people do the same by their religion. Charles Dickens
people scary alive
I have heard it said that as we keep our birthdays when we are alive, so the ghosts of dead people, who are not easy in their graves, keep the day they died upon. Charles Dickens
people enemy
Some people are nobody's enemies but their own Charles Dickens
people romance wonder-woman
Superman/Wonder Woman, people expected, I guess, a lot of romance, or maybe something that wasnt emotionally deep. Who knows? Charles Soule
perfect gentleman intimacy
He that can enjoy the intimacy of the great, and on no occasion disgust them by familiarity, or disgrace himself by servility, proves that he is as perfect a gentleman by nature as his companions are by rank. Charles Caleb Colton
perfect religion nuisance
Missionaries are perfect nuisances and leave every place worse than they found it. Charles Dickens
perfect may matter
No matter how far we may wander from the Lord’s perfect will for our lives, we are always welcome back. Charles Stanley
perfect waiting heaven
If you wait for a perfect church, you must wait until you get to heaven; and even if you could find a perfect assembly on earth, I am sure they would not admit you to their fellowship, for you are not perfect yourself. Charles Spurgeon
perfect glory burden
Take up your own daily cross; it is the burden best suited for your shoulder, and will prove most effective to make you perfect in every good word and work to the glory of God. Charles Spurgeon
perfect judgement world
In a perfect world, there would be no censorship, because there would be no judgement. Alanis Morissette
perfection technique invisible
If you obey the technique to perfection, that technique will become invisible. Alan Chadwick
perfect perfect-love knows
Perfect love knows no because Aiden Wilson Tozer
perfect form
Why don't we just expand ourselves into our perfect form, our perfect being? Chogyam Trungpa
phones looks lists
If someone is interested in working with me, I would much rather them email me and we sit down or get on the phone, than them look at a client list and decide if I'm worth it or not. It should be based on work, and based on how we get along. As opposed to like, "Oh, he's worked with this, this, and this. Let's go. That's fine." Chris Black
phones nba novelists
As a novelist, there are three phone calls you never expect to receive in your lifetime because if you waited for them you would grow despairing - one calling from Stockholm with a Swedish accent, one from the NBA, and one from Oprah Winfrey. Chris Bohjalian
phones differences profound
I always used to reach for the cigarette when the phone rang, and I figured nobody would ever call me in Tokyo. The time difference is so profound it's, like, already September in Tokyo, and I figured nobody would be able to work it out. David Sedaris
phones people too-late
Right, my phone. When these things first appeared, they were so cool. Only when it was too late did people realize they are as cool as electronic tags on remand prisoners. David Mitchell
phones way messages
Sending a message on a mobile phone is not the most natural of ways to communicate. The keypad isn't linguistically sensible. David Crystal
phones agency car
You should definitely have a travel agent. Why go through all the hassle of dealing with airlines, hotels, and rental-car agencies yourself, only to see the arrangements get all screwed up, when with just a single phone call you can have a trained professional screw them up for you? Dave Barry
phones medicine doctors
I become faint and nauseous during even very minor medical procedures, such as making an appointment by phone. Dave Barry
phones people online
The future of mobile is the future of online. It is how people access online content now. David Murphy
phones mind email
Happiness is a clear mind. A clear and sane mind knows how to live, how to work, what emails to send, what phone calls to make, and what to do do to create what it wants without fear. Byron Katie
pride sickness breaking-down
There is something in sickness that breaks down the pride of manhood. Charles Dickens
pride men becoming
There is this paradox in pride - it makes some men ridiculous, but prevents others from becoming so. Charles Caleb Colton
pride keepers
Pride requires very costly food-its keeper's happiness. Charles Caleb Colton
pride self attractive
Pride, like the magnet, constantly points to one object, self; but, unlike the magnet, it has no attractive pole, but at all points repels. Charles Caleb Colton
pride may charity
Whenever we find ourselves more inclined to persecute than to persuade, we may then be certain that our zeal has more of pride in it than of charity. Charles Caleb Colton
pride common-sense prudence
Pedantry prides herself on being wrong by rules; while common sense is contented to be right without them. Charles Caleb Colton
pride cutting animal
The most ridiculous of all animals is a proud priest; he cannot use his own tools without cutting his own fingers. Charles Caleb Colton
pride self vanity
Pride differs in many things from vanity, and by gradations that never blend, although they may be somewhat indistinguishable. Pride may perhaps be termed a too high opinion of ourselves founded on the overrating of certain qualities that we do actually possess; whereas vanity is more easily satisfied, and can extract a feeling of self-complacency from qualifications that are imaginary. Charles Caleb Colton
pride charity may
Many ... begin to make converts from motives of charity, but continue to do so from motives of pride. ... Charity is contented with exhortation and example, but pride is not to be so easily satisfied. ... Whenever we find ourselves more inclined to persecute than persuade, we may then be certain that our zeal has more of pride in it than of charity. Charles Caleb Colton
romance nostalgia certain
There's a certain nostalgia and romance in a place you left. David Guterson
romance hamburgers vanilla
I'll take you to Mickey D's," said Sean. "I'll buy you a hamburger." Annie was not thrilled. Sean's offer did not compare to offers made in other centuries. "And fries," Sean said. "And a vanilla milkshake." Annie remained unthrilled. "Okay, okay. You can have a Big Mac." Romance in my century, she thought, is pitiful. Caroline B. Cooney
romance together back-together
Why don't the Beatles get back together? Why don't nobody sing of romance? Billy Joel
romance firsts intimacy
Not for the first time, I reflected that intimacy and romance are not synonymous. Diana Gabaldon
romance soul losing
Oh, aye, Sassenach. I am your master . . . and you're mine. Seems I canna possess your soul without losing my own. Diana Gabaldon
romance alcohol should
Romance, like alcohol, should be enjoyed but must not be allowed to become necessary. Edgar Friedenberg
romance faces romanticism
I have nothing against romanticism. I'm all for it. I'm helpless in the face of romance. Bill Nighy
romance style flavor
Cassini is different -- it's a mission of enormous scope and is being conducted in grand style. It is much more sophisticated than Voyager, ... I can't say it's got that flavor of romance, though. Voyager was very romantic. Cassini is spectacular. Carolyn Porco
romance literature should
Life should imitate romance literature far more often. Charlaine Harris
send
We want to send Carl out on top. Aaron Gray
sending sure
We're making sure that we're sending the right message. Jerry Gonzalez
send
I eat so much mayonnaise they were going to send me to the Mayo Clinic. Tom Robbins
send time
Most of the time you send Rad back out there. But this isn't most of the time any more. Ron Gardenhire
send
Most of the time, you'd send (Radke) back out there, but this isn't 'most of the time' anymore. Ron Gardenhire
send
Yes, I will send that in. I feel like that one was obvious. Joe Gibbs
sending surface work
Sending Minerva to the surface did not work. Junichiro Kawaguchi
sending sounds
Sending in the commandos sounds very hip, but it isn't the whole solution. Sunita Narain
sending silly start stupid
Sending him back out there, that's a little silly to try to do something stupid with a man's career. We haven't done that to him all year, and we weren't going to start today. Ron Gardenhire
technology hands people
Technology is destructive only in the hands of people who do not realize that they are one and the same process as the universe. Alan Watts
technology civilization goal
...the materialism of modern civilization is paradoxically founded on a hatred of materiality, a goal-oriented desire to obliterate all natural limits through technology, imposing an abstract grid over nature. Alan Watts
technology fit lifestyle
The success of SYNC is another proof point that we are doing just that. We will continue to innovate and expand the capability of SYNC by integrating even more new technologies that fit our customers’ lifestyles. Alan Mulally
technology matter watches
It doesn't matter what the technology is - no one will watch a Peter Greenaway film anyway. Alan Parker
technology fields needs
The computing field is always in need of new cliches. Alan Perlis
technology thinking people
I think it is inevitable that people program poorly. Training will not substantially help matters. We have to learn to live with it. Alan Perlis
technology bird worms
In software systems it is often the early bird that makes the worm. Alan Perlis
technology two benefits
Technology is always a two-edged sword. It will bring in many benefits, but also many disasters. Alan Moore
technology amish kind
I'm remote from most technology to the point that I'm kind of Amish. Alan Moore
time son boys
A boy's story is the best that is ever told. Charles Dickens
time fool calendars
Tomorrow! It is a period nowhere to be found in all the registers of time, unless, perchance, in the fool's calendar. Charles Caleb Colton
time all-things
Time is the measurer of all things, but is itself immeasurable, and the grand discloser of all things, but is itself undisclosed. Charles Caleb Colton
time retreat tides
Time ... advances like the slowest tide, but retreats like the swiftest torrent. Charles Caleb Colton
time two black
Time,- that black and narrow isthmus between two eternities. Charles Caleb Colton
time looks one-thing
To look back to antiquity is one thing, to go back to it is another. Charles Caleb Colton
time world overcoming
Time is the most subtle yet the most insatiable of depredators, and by appearing to take nothing is permitted to take all; nor can it be satisfied until it has stolen the world from us, and us from the world. It constantly flies, yet overcomes all things by flight; and although it is the present ally, it will be the future conqueror of death. Charles Caleb Colton
time journey men
Much may be done in those little shreds and patches of time which every day produces, and which most men throw away. Charles Caleb Colton
time opportunity enemy
Time, the cradle of hope.... Wisdom walks before it, opportunity with it, and repentance behind it: he that has made it his friend will have little to fear from his enemies, but he that has made it his enemy will have little to hope from his friends. Charles Caleb Colton
took
We started out sluggish. It took us a while to get in our groove. Jason Swearingen
took
Vail's a very important place for me. Everyone kind of took me in and accepted me in that town, and they still have to this day. I wouldn't be a downhill skier if I hadn't been there. Lindsey Vonn
took worked
When we got to our feet, I wanted to make something happen, so I took a chance. It worked out for me. Nate Gallick
took
Unfortunately, it took us this long to do this. Eric Norris
took
When they took the lead, we showed some toughness. Frank Haith
took
I think I just took a while to know myself. I went on a journey to find out. I was a bit wild. Trinny Woodall
took
Our Redeemer took upon Himself all the sins, pains, infirmities, and sicknesses of all who have ever lived and will ever live. James E. Faust
took
She never complained about being sick. She took it all in stride. Barbara Green
took tour
Mohammad and I took a tour of the devastation. Jalal Farzaneh
women resentment consequence
Women generally consider consequences in love, seldom in resentment. Charles Caleb Colton
women flower sun
Pleasure is to women what the sun is to the flower; if moderately enjoyed, it beautifies, it refreshes, and it improves; if immoderately, it withers, deteriorates and destroys. Charles Caleb Colton
women want ornaments
Modesty is the richest ornament of a woman ... the want of it is her greatest deformity. Charles Caleb Colton
women intellectual female
A high degree of intellectual refinement in the female is the surest pledge society can have for the improvement of the male. Charles Caleb Colton
women doe attention
The plainest man who pays attention to women, will sometimes succeed as well as the handsomest man who does not. Charles Caleb Colton
women modest bashful
Women that are the least bashful are often the most modest. Charles Caleb Colton
women decorum length
Women do not transgress the bounds of decorum so often as men; but when they do, they go greater lengths. Charles Caleb Colton
women said mould
She's the sort of woman now,' said Mould, . . . 'one would almost feel disposed to bury for nothing: and do it neatly, too! Charles Dickens
women want today
You see what happens today. Women act like men and want to be treated like women. Alan Jay Lerner