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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
arriving poet san talk
Let us go and talk with the poets. (on arriving in San Francisco) Joaquin Miller
arriving avoid cap conclusion good near process tuition
The process of arriving at the tuition was different this year.... The conclusion was that ... there wasn't a good way to avoid getting near the tuition cap this year. Greg Hand
arriving attitude biggest senate
The single biggest surprise about arriving to the Senate is the defeatist attitude here. Ted Cruz
arriving killing time-to-kill
[To audience members who were arriving late] You haven't missed a thing, I was just killing time 'til you got here Billy Connolly
arriving boxes scripts
It's not like I have boxes of scripts arriving at my door. Kristen Wiig
arriving cause confusion customer easy figure supposed traveling
This will not cause confusion for the traveling public. This is going to be very easy for the customer arriving at the checkpoint to figure what they're supposed to do. We'll make that very, very clear. Kip Hawley
arriving bit coming days last people player success suffer three training until valuable year
Last year we think we did suffer a little bit because we had people coming in every two or three days. People were not arriving until the last two or three days of training camp. To really have all but one player here from the beginning, we think is going to be very, very valuable to any success we have this season. Roger Griffiths
arriving choosing head north northeast toward turn
Many northerners just arriving here have not even unpacked choosing to turn around and head north by northeast back toward Jacksonville, into Georgia, etc., Don Anderson
arriving building expected people side
The people arriving on this side of the building are expected to fend for themselves. We have some water. Terry Ebbert
considerate considerate-and-caring be-considerate
He who doesn't consider himself is seldom considerate of others. David Seabury
consider freedom government
I consider myself a kind of a one-man government-in-exile. I don't want to call it a government - let's call it one man's idea of American freedom in exile. Michael Moriarty
consider evening luxurious people
The people who live there don't consider it a casino. It's a luxurious place to go for an evening out. Bill Thompson
consider direct economics given industry itself number percent point
The point is the industry itself shouldn't be straddled with constraints that many of our direct competitors don't have. We feel the number 30 percent isn't really justified. It's very, very arbitrary. We consider a number around 40 percent to be more appropriate given the economics in the industry. Jim Cicconi
consider senior until wait year
We usually wait until an athlete's senior year to consider going to Arcadia. Chris Hanson
consider empower ladies ourselves strive
We strive for excellence, and we empower women. We consider ourselves the ladies on campus. Michelle Clark
consider
When you've been here, and you consider it your house, you're at home. Naylond Hayes
consider involved love meet people
When you usher, you meet a lot of people who are not involved with the theater, but (who still consider it) a very big part of their lives, and love to see the shows, Grace Morgan
considered
I always considered technical musicianship as something you should be ashamed of - I don't know why. Laurent Brancowitz
easy monopoly legislation
I'm not denying that monopolies are terrible things, but I am denying that it is readily easy to resolve them through legislation of that nature. Alan Greenspan
easy crosses lays
Be hard on yourself and easy on others. Carry your own cross but never lay one on the back of another Aiden Wilson Tozer
easy easy-things
Americans really don't understand the Japanese nature, but it's not an easy thing to understand. Cary-Hiroyuki Tagawa
easy it-takes-time take-time
Change isn't easy, it takes time. Caroline Kennedy
easy hard
Things are so easy to do, so hard to undo. Catherine Ryan Hyde
easy fight leaving problem ready union work
The percentages are low, no question, ... The work is leaving the workers. This outsourcing is a problem for union and non-union workers. Labor's never had it easy but we're ready to fight for workers' rights. Jack Shea
easy faces game half knew second stay stops tough
We started the game with stops and conversions, and we started the second half with stops and conversions. ? We knew we had to make it tough for them to score. We had to stay in their faces all night. No easy baskets. Louis Orr
easy struggled
We struggled through it, and nothing ever comes easy for us. Frank Robinson
easy embark feeling feels felt harder keeps knew might since time toes whenever
The more I act, the harder it gets, since I feel like I still have so much to learn. Whenever I embark on a new project, it always feels like the first time. If it were easy to me and I felt like I knew everything, my acting might have been different. I think the feeling of 'newness' keeps me on my toes and concentrated. Lee Byung-hun
faster players ran team
The other team had a lot more Afro-American players than we did and they ran a lot faster than we did. Fisher DeBerry
faster downsizing ifs
Here's the thing, you just have to drive a lot faster, and if you don't get there, we're both fired. Bill Murray
faster original project record
My original project was called 'The Wheel'; there's a record out there called 'Desire & The Dissolving Man,' 'The Memory Of Loss' as well. There's also 'Falling Faster Than You Can Run,' also 'Closer'; all of that's on our website. Nathaniel Rateliff
faster gets natural ways
We're going to get her times down faster once she gets in shape. She still has a ways to go on that, but she has a lot of natural ability. Megan Smith
faster until
We're going to keep going until we're faster than those guys, Steve Jobs
faster figure school students
We're going to have to figure out a way for students to go through school faster so more can come in. Sandra Smith
faster plus quicker
We're faster and plus we play a quicker game. Anatol Popovich
faster
Ultimately, it will be much faster than it is now. Joerg Appenzeller
faster handle loans number process
The process is very seamless, and allows us to handle more loans with the same number of people. As we go forward, we can give the brokers a faster response. Craig Forman
roughly
Jaipur, like Florence or Kyoto, other artisan-rich cities to which it roughly compares, has always been known for its craftsmanship. Hanya Yanagihara
seems interfere
Work doesn't seem to interfere with my life. I have time for everything, even time to be alone. Carolina Herrera
seems situation stop trying
We're in a situation where we just can't stop the bleeding. We keep trying to put band-aids on the wound, but nothing seems to help. John Sacchi
seems work
When you stop thinking about something, the idea comes to you. It seems to work. Jim Rash
seems
We're going to do what we've been doing all year. It seems to be working fine. Nicole Piggott
seems commonplace
Anything seems commonplace, once explained. Arthur Conan Doyle
seems
I do feel as if... Look, I think I'm a very kind of ordinary person, and it seems to me that things that are of interest to me will probably be of interest to other people. I'm not exceptional; I don't have exceptional thoughts. Kate Grenville
seems worlds
It seems like there are two worlds out there - one that has revolved around 'Breaking Bad,' and then the one that I've been in, which just kind of observes it from afar. Todd Rundgren
seems
There's something about [cyclically] doing something over and over and over that seems to be particularly demotivating. Dan Ariely
seems ifs
I have to tell you I never in my life anticipated getting this old, this fast. It seems as if I were 25 just a few days ago. Ben Stein
technology hands people
Technology is destructive only in the hands of people who do not realize that they are one and the same process as the universe. Alan Watts
technology civilization goal
...the materialism of modern civilization is paradoxically founded on a hatred of materiality, a goal-oriented desire to obliterate all natural limits through technology, imposing an abstract grid over nature. Alan Watts
technology fit lifestyle
The success of SYNC is another proof point that we are doing just that. We will continue to innovate and expand the capability of SYNC by integrating even more new technologies that fit our customers’ lifestyles. Alan Mulally
technology matter watches
It doesn't matter what the technology is - no one will watch a Peter Greenaway film anyway. Alan Parker
technology fields needs
The computing field is always in need of new cliches. Alan Perlis
technology thinking people
I think it is inevitable that people program poorly. Training will not substantially help matters. We have to learn to live with it. Alan Perlis
technology bird worms
In software systems it is often the early bird that makes the worm. Alan Perlis
technology two benefits
Technology is always a two-edged sword. It will bring in many benefits, but also many disasters. Alan Moore
technology amish kind
I'm remote from most technology to the point that I'm kind of Amish. Alan Moore
telephones conversation objects
Saying that cultural objects have value is like saying that telephones have conversations. Brian Eno
telephones world outside-world
I disconnect the telephone to keep the outside world in it's correct place. Chuck Palahniuk
telephones would-be teach
There would be far fewer accidents if we could only teach telephone poles to be more careful. Ambrose Bierce
telephones bills saws
I thought talk was cheap until I saw our telephone bill. Henny Youngman
telephones criticize
To criticize Facebook is to criticize the telephone. Jesse Eisenberg
telephones ifs
I stay away from the telephone if at all possible. Lee Trevino
telephones email assuming
I assume everything I'm saying in an email or saying on the telephone is being looked at. Michael Moore
telephones cyberspace where-you-are
Cyberspace is where you are when you're on the telephone. William Gibson
telephones lobster restaurants
I do not understand why, when I ask for grilled lobster in a restaurant, I'm never served a cooked telephone. Salvador Dali
understanding mind half
It is with disease of the mind, as with those of the body; we are half dead before we understand our disorder, and half cured when we do. Charles Caleb Colton
understanding vietnam realizing
As I come to understand Vietnam and what it implies about the human condition, I also realize that few humans will permit themselves such an understanding. Alan Moore
understanding sides stories
If you only hear one side of the story, you have no understanding at all. Chinua Achebe
understanding levels fox-news
There are a lot of folks at Fox News who bring a certain level of sophistication to their understanding of politics. David Shuster
understanding safe too-much
This was the consequence of seeing too much and understanding the horrible truth: No one is safe. The world is not manageable. David Sedaris
understanding realizing understood
I'd always thought that I understood this, but lately I realize that what I call "understanding" is basically just fantasizing. David Sedaris
understanding humanity different
What helps you as an actor when it comes to roles is that deeper understanding of so many different fractions of humanity. Because oftentimes, even in comedy, there is conflict. David Koechner
understanding curiosity kind
Understanding is a kind of ecstasy Carl Sagan
understanding joining magnificence
The very act of understanding is a celebration of joining, merging, even if on a very modest scale, with the magnificence of the Cosmos. Carl Sagan