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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
almost fully investors money rate recommend simply since work
I almost always recommend investors get fully invested, since it's better to put your money to work than to let it simply track the rate of inflation. Louis Navellier
almost badly people provided schooling
The majority of people in Angola were not provided with any kind of schooling and were completely illiterate, very badly paid, and treated almost as slaves. Louis Leakey
almost begging ceremony good people private putting script
As a teenager, in my songbook, I used to script what my lighting would be like. I used to dance in my roo;, it was like putting myself in a trance, and making myself feel good about things, almost like a private ceremony of begging people to like you. Mika
almost body goes hip hurdles knee leg move split tells trainer
I hate leg exercises. I hate one-legged squats. I hate the hurdles and the split squats. I hate all the leg exercises. I know they help me, and I'm able to move around and don't have knee problems, and my hip doesn't hurt anymore, but when my trainer tells me I have to do them, I almost feel like my body goes into convulsions. Michael Strahan
almost along broken gets good hard pushed unless writer written
Nothing good gets written without the writer suffering along the way, in my opinion. Writing should be a pleasure, but unless you feel almost broken many, many times in the journey to a novel, you haven't pushed yourself hard enough. Mohsin Hamid
almost apologetic avoiding bars based brutal change exposed films flow money people suit truth
After 'Chandni Bar' there was a shutdown of such bars in Mumbai. After 'Page 3' people started avoiding such events. 'Traffic Signal' exposed the money flow through the mafia. I'm not apologetic about the brutal truth in my films. Almost 70% of my films are based on reality, and 30% I fictionalize or change to suit my film. Madhur Bhandarkar
almost fat great percentage product
The percentage of fat in this product here is almost 50 percent fat. But it's turkey. But because it's turkey, we think we're doing a great job. Margo Rodriguez
almost extremely following line sad
We are pretty much approaching the line of an almost Serb-free Kosovo, which is an extremely sad phenomenon. One exodus is following another. Kris Janowski
almost exception few odds people talked
We've already talked to people and it's completely safe, ... And with the exception of a few odds and ends, we're almost done. Chuck D.
business soul prosperity
Industry is the soul of business and the keystone of prosperity. Charles Dickens
business fighting men
An Irish man fights before he reasons, a Scotchman reasons before he fights, an Englishman is not particular as to the order of precedence, but will do either to accommodate his customers. Charles Caleb Colton
business men morality
Most men are individuals no longer so far as their business, its activities, or its moralities are concerned. They are not units but fractions. Charles Dickens
business clever men
The first rule of business is: Do other men for they would do you Charles Dickens
business law brain
Contract law is essentially a defensive scorched-earth battleground where the constant question is, "if my business partner was possessed by a brain-eating monster from beyond spacetime tomorrow, what is the worst thing they could do to me?" Charles Stross
business past derivatives
It seems superfluous to constrain trading in some of the newer derivatives and other innovative financial contracts of the past decade. The worst have failed; investors no longer fund them and are not likely to in the future. Alan Greenspan
business colleagues depends
...our market system depends critically on trust-trust in the word of our colleagues and trust in the word of those with whom we do business. Alan Greenspan
business years risk
What we have found over the years in the marketplace is that derivatives have been an extraordinarily useful vehicle to transfer risk from those who shouldn't be taking it to those who are willing to and are capable of doing so. Alan Greenspan
business greatness views
I have found no greater satisfaction than achieving success through honest dealing and strict adherence to the view that, for you to gain, those you deal with should gain as well. Alan Greenspan
economics taxes
Whatever you tax you get less of. Alan Greenspan
economic plant profile
While it is true that we must seek value added industries like food processing plants and call center operations, we must do what is necessary to expand and develop our economic profile. Alan Autry
economic strengthen
We want to strengthen the commercial, economic relationship, Adnan Badran
economic currents flawed
The current economic system is fundamentally flawed and inevitably destructive. David Suzuki
economic verge
We are probably on the verge of an economic recovery. Stephen Leeb
economic luxury stage
We are at the stage of economic development where we do not have the luxury to be wasteful, Zeng Peiyan
economic market moment remarkably time virtually
We are at a moment here in economic time that things are really going remarkably well on virtually all fronts and that's why you see the market at all-time highs. Mary Farrell
economic figures last looks markets moving narrow oil percent push reason three waiting
We're in a narrow range, moving around about 1 percent over the last three days, and it looks like the markets are waiting for some economic figures or waiting on oil because there's really no reason to push anything now. David Briggs
economic-inequality long lasts
I will always have enough money to last the rest of my life...as long as I don't buy anything. Ed Asner
educational keys doors
A very little key will open a very heavy door. Charles Dickens
education teaching brain
Pedantry crams our heads with learned lumber and takes out our brains to make room for it. Charles Caleb Colton
education book men
He who studies books alone will know how things ought to be, and he who studies men will know how they are. Charles Caleb Colton
education mind armor
The acquirements of science maybe termed the armor of the mind. Charles Caleb Colton
education teaching knowledge
Examinations are formidable even to the best prepared, for the greatest fool may ask more than the wisest man can answer. Charles Caleb Colton
education prayer men
An unschooled man who knows how to meditate upon the Lord has learned far more than the man with the highest education who does not know how to meditate. Charles Stanley
educational clothes giving
Our educational system in its entirety does nothing to give us any kind of material competence. In other words, we don't learn how to cook, how to make clothes, how to build houses, how to make love, or to do any of the absolutely fundamental things of life. Alan Watts
education learning buddhism
A scholar tries to learn something everyday; a student of Buddhism tries to unlearn something daily. Alan Watts
education country government
The United States government has the obligation to educate all young people in this country. Al Sharpton
fetch means people stream
I know what it means to go to the stream to fetch water... what it means when people are poor and don't have enough to eat. It's not enough to say you know about poverty. You have to live it. Ngozi Okonjo-Iweala
fetch
Things are worth what they will fetch at a sale Edward Coke
fetch saws embarrassed
I was very embarrassed when my canvases began to fetch high prices. I saw myself condemned to a future of nothing but Masterpieces. Henri Matisse
fetch horses morning
I, a late riser, fantasise about getting up every morning at 5 A.M. to fetch the horses in from the fields. Meg Rosoff
fetch pat throw
Sometimes I think being an actor is like being a dog for a director; it's like they throw a stick, and you want to fetch it and bring it back to them. You want a pat on the head for it. Joel Edgerton
fetch meant tuesday
Then, on Tuesday night, we were told that we could fetch our passports. It meant we could get back home. Sechan Pillay
fetch mother obey thy unto
And his mother said unto him, Upon me be thy curse, my son: only obey my voice, and go fetch me them. Bible Bible
fetch pathos poignancy work
Pathos and poignancy are, to me, tactics and techniques; in my work as a writer, I fetch them from my toolbox and use them as required. Michel Faber
given no-hope pledge
God has given no pledge which He will not redeem, and encouraged no hope which He will not fulfill. Charles Spurgeon
given guy guys perception
The perception now is that (Woods) is still the guy to beat. But I don't think guys think it's a given that he's going to win. Lee Janzen
given park rules
We've already given them an extension. It's really simple: The rules of the park have to be followed. Sharon Stewart
given life lived name people talk tony
I hate it when people talk about Tony Curtis and say: 'His real name was Bernie Schwartz... ' That was just the name that he was given at birth. It's not the person he lived his life with, and became. Nicolas Roeg
given movies sad
A lot of my movies have come to be thought about only years after the fact, and I'm sad about that but also happy about it in a way, as it's given them longevity. Nicolas Roeg
given relevant considering
I have given up considering happiness as relevant. Edward Gorey
given hoard wealth
Wealth that you hoard is not yours; wealth that you have given is really yours. Sathya Baba
given heck love sharks shocked
What the Sharks did, it shocked the heck out of me. We've always been rivals, but I think they know how much I love this game, and how much I've given to it. Luc Robitaille
given
We have assumed control where once we worked with what we were given. Bill McKibben
lessons shapes pay
Everything shapes you to be the person you are today. Sometimes hard lessons pay off dividends. Al Jourgensen
lessons matter facts
No matter what you do, you can never please everyone. And that was the hardest lesson to learn. In fact, I'm still learning it. Chris Colfer
lessons painful evolve
Unless you continually work, evolve, and innovate, you'll learn a quick and painful lesson from someone who has. Cael Sanderson
less looking toward
We are looking less favorably toward 2016 bidding at this moment, Peter Ueberroth
less mean point push start sure year
We are at the point of the year where if you push him back, it could mean one less start at the end of the year. We need to make sure that he can pitch. If we do push him back, we want to make sure we have the matchups we need at the end of the season. Mike Scioscia
lessons used teach
I used to teach dance lessons. Eartha Kitt
lessons rewards hell
The lesson is, the rewards in life don't always go to the biggest, or the bravest, or the smartest. The rewards go to the dogged; and when your going though hell, to the person who just keeps going. Bear Grylls
lessons-to-be-learned alive process
Success is a process that continues, not a status that you reach. If you are alive, there are lessons to be learned. Denis Waitley
lessons firsts given
To know ourselves, is agreed by all to be the most useful Learning; the first Lessons, therefore, given us ought to be on that Subject. Eliza Haywood
lousy players whatever
We have not been good. The players haven't been good. You can say whatever you want. I have done a lousy job. Bob Stoops
lousy map somebody trouble
You would think that somebody would put out a map of the Kettle Moraine Scenic Trail, ... They went to enough trouble to put up the lousy signs. Jim McKenna
lousy report
The report is lousy but it is much better underneath. Eli Lustgarten
lousy negative reflection
I don't see this as a negative or a positive. I see it as a reflection of the already lousy fundamentals in the business. Anthony DiClemente
lousy sell
The first thing they need to do is sell the lousy stores. Eric Bosshard
might stairs lorry
Mr Lorry asks the witness questions: Ever been kicked? Might have been. Frequently? No. Ever kicked down stairs? Decidedly not; once received a kick at the top of a staircase, and fell down stairs of his own accord. Charles Dickens
might use disaster
But ah! disasters have their use; And life might e'en be too sunshiny... Charles Stuart Calverley
might god-bless bless
God blesses us so that we might bless others! Charles Stanley
might wells ifs
I thought, "Well if I'm gonna react might as well overreact! Alan Moore
might quiet
Dead … might not be quiet at all. Chris Bohjalian
might outcomes infinity
For every action, there's an infinity of outcomes. Countless trillions are possible, many milliards are likely, millions might be considered probable, several occur as possibilities to us as observers - and one comes true. China Mieville
might naked world
Alan Zweibel is the funniest writer in the world. He might be even funnier when he's naked, but I'm afraid to find out. Dave Barry
might tools ifs
If Mozart had power tools, there's no telling how great his music might have been. Dave Barry
might ruins bourgeoisie
The bourgeoisie might blast and ruin its own world before it leaves the stage of history. Buenaventura Durruti
money giving grace
Riches may enable us to confer favors, but to confer them with propriety and grace requires a something that riches cannot give. Charles Caleb Colton
money evil gains
To cure us of our immoderate love of gain, we should seriously consider how many goods there are that money will not purchase, and these the best; and how many evils there are that money will not remedy, and these the worst. Charles Caleb Colton
money greatest-wealth want
Wealth after all is a relative thing since he that has little and wants less is richer than he that has much and wants more. Charles Caleb Colton
money battle half
economy is half the battle of life; it is notso hard to earn money as to spend it well. Charles Spurgeon
money people saving
So many people of wealth understand much more about making and saving money than about using and enjoying it. They fail to live because they are always preparing to live. Alan Watts
money thinking people
The reason we have poverty is that we have no imagination. There are a great many people accumulating what they think is vast wealth, but it's only money... they don't know how to enjoy it, because they have no imagination. Alan Watts
money children clothes
And money is not something to go mad about ... Money is for food and clothes and comfort, and a visit to the pictures. Money is to make happy the lives of children. Alan Paton
money law issues
As long as we issue fiat currency, I see no alternative to a legal tender law. Alan Greenspan
money gold wealth
Deficit spending is simply a scheme for the confiscation of wealth. Alan Greenspan
normal
How can you be afraid of women?” “Those ain’t normal women. Dave Barry
normal being-a-woman taboo
All the things that are taboo are the things that are not normal, and all the things that are not normal are the things that are exclusively about physically being a woman. Caitlin Moran
normal shot today
We've all bowled at Cadillac, but today wasn't like the normal Cadillac. It was a very playable shot but just a little different. Scott Carpenter
normal played settled
We started off very poorly. But we know what we can do. We just settled down and played our normal game. Joe Johnson
normal particular produce quantities traces
Coproporphyrin in particular is widespread; traces are present in normal urine and also in yeast. In special cultures, yeast can be made to produce considerable quantities of coproporphyrin. Hans Fischer
normal persons
I had to bring myself back down to being a normal person again. Aidan Quinn
normal appetite wells
I have an appetite for the normal in my life, as well as the abnormal. Benedict Cumberbatch
normal possible
We want it to be as normal as possible for the kids. Max Miller
normal possible setting
We want it be as normal a setting as possible and not have them stigmatized as being retarded. Jim Hall
skills honey taste
Most plagiarists, like the drone, have neither taste to select, industry to acquire, nor skill to improve, but impudently pilfer the honey ready prepared, from the hive. Charles Caleb Colton
skills generations novelists
We're currently living with a generation of established novelists who are embarrassingly out of date with respect to social networking, internet skills, and so on. Charles Stross
skills perception taoism
But the transformation of consciousness undertaken in Taoism and Zen is more like the correction of faulty perception or the curing of a disease. It is not an acquisitive process of learning more and more facts or greater and greater skills, but rather an unlearning of wrong habits and opinions. As Lao-tzu said, "The scholar gains every day, but the Taoist loses every day. Alan Watts
skills age lucky
And the maestro surely wielded the chairman's baton with extraordinary skill. His stellar record suggests that the only right answer to the age-old question of whether it is better to be lucky or good may be: both. Alan Blinder
skills cards world
I don't know if this is an illusion but I would love to be able to take my card-throwing skills and be able to puncture a watermelon. Now I know I can take this question and say, "I would want to solve the economic problems in the world" - but I want to stick that card in that watermelon. Dave Franco
skills judging-yourself luck
Don't confuse luck with skill when judging others, and especially when judging yourself. Carl Icahn
skills class looks
You've got to look and pick your shots - and that's where your class and skill comes out. Billy Joe Saunders
skills mind soil
In the productions of the mind, as in those of the soil, the gifts of nature are excelled by industry and skill . . . Edward Gibbon
skills energy kind
Picasso is still influencing me. Of course, I haven't got that kind of energy, or skill. David Hockney
teachers
If we are to stop bullying in schools, we have to start with teachers and administrators. If we want to stop it, we have to stop it. Chris Crutcher
teachers trying
The teachers are trying to build the same culture in the classroom as we're building in the organization. Wendy Kopp
teachers writer
I think you become a writer when you stop writing for yourself or your teachers and start thinking about readers. Avi
teachers
As the daughter of two teachers with first-class degrees, I'd always seen myself as a duffer by comparison. Mary Quant
teachers
Saturdays we always have a lot of browsers -- teachers and tourists. Dave Craig
teachers
Some teachers are better with adults and some aren't. Peggy Smith
teachers
If you've ever been in a classroom, you know these teachers are underpaid. Catherine Johnson
work quality may
Although profoundly "inconsequential," the Zen experience has consequences in the sense that it may be applied in any direction, to any conceivable human activity, and that wherever it is so applied it lends an unmistakable quality to the work. Alan Watts
work apology giving
Give a civil servant a good case and he'll wreck it with clichés, bad punctuation, double negatives, and convoluted apology. Alan Clark
work mean doing-nothing
If I am doing nothing, I like to be doing nothing to some purpose. That is what leisure means. Alan Bennett
work sleep thinking
A gentleman ... sleeps at his work. That's what work's for. Why do you think they have the SILENCE notices in the library? So as not to disturb me in my little nook behind the biography shelves. Alan Ayckbourn
work play able
You've got to get good habits of working hard so that when that play comes up during the regular season that you're able to complete it and do it the right way. Al Kaline
work people kind
Japanese people tend to be much better adjusted to the notion of work, any kind of work, as honorable. Akio Morita
workout training cardio
I do a dance-based cardio workout infused with circuit training, and emphasizing strength and alignment. Chloe Sevigny
work-out effort feels
If I put forth a legitimate effort, then I feel like, if that doesn't work out, that's all I can do. Dave Chappelle
work-out levels mail
I always take a relationship to the next level. If that works out, I take it to the next level after that, until I finally reach that level when it becomes absolutely necessary for me to leave. Dave Chappelle