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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
beginners winner
There never was a winner, who wasn't a beginner. Denis Waitley
beginners children customers fishing good percent start tailor
One of the good things is we don't tailor to just the experienced fishermen. I would say 90 percent of our customers are beginners, and not just children with no fishing experience. Probably 60 percent are adults who are beginners and don't know what to do to start out. Aaron Hungerford
beginners realizing
We are all beginners, it just takes some of us longer to realize it Chuck Miller
beginners
There are so many beginners in the water. My friends will be like, 'They don't know what to do,' but I'll try to give them a hand. We were all there once. Sanoe Lake
beginners both brave bravery caused confident early ends fall hurt injuries limits occur push riders season seen ski traumatic
Early season bravery has caused some of the most traumatic injuries I've seen in 21 years in the ski business. Injuries in the first part of the season occur at both ends of the spectrum. Beginners often get hurt because they don't know how to fall or they are in over their heads. Better riders get hurt because they are over confident and push their limits to far. Ed Youmans
beginners done kind
It's about doing things that you haven't done before, where you're still kind of a beginner, and not resting on your laurels. Caterina Fake
beginners bring christian lots maximize million number opportunity pipeline science web
I look at the Web as an opportunity to have a million doorways to the Christian Science Monitor. I think of it as a progression from one end, where it's free, to the other end, where it's paid. The pipeline has to be really big at the out end to bring in lots of beginners if you want to maximize the number of subscribers at the other end. Stephen Gray
beginners gentle good information kids left purple recall third toe
He's such a gentle person, very patient, and he can give information to kids and beginners in a way that they understand. He has good recall of details. You know, like the third toe is always purple on the left foot, that kind of stuff. Sue Johnston
beginners looks something-new
I'm always tryin' to do something new, tryin' to look like a beginner. Meshell Ndegeocello
class two people
Mr Jarndyce, and prevented his going any farther, when he had remarked that there were two classes of charitable people: one, the people who did a little and made a great deal of noise; the other, the people who did a great deal and made no noise at all. Charles Dickens
class words-of-wisdom success-of-others
The worst class of sum worked in the every-day world is cyphered by the diseased arithmeticians who are always in the rule of Subtraction as to the merits and successes of others, and never in Addition as to their own. Charles Dickens
class safety age
Though we are perpetually bragging of it [the middle class] as our safety, it is nothing but a poor fringe on the mantle of the upper class. Charles Dickens
class citizens degradation
The American elite is almost beyond redemption. . . . Moral relativism has set in so deeply that the gilded classes have become incapable of discerning right from wrong. Everything can be explained away, especially by journalists. Life is one great moral mush--sophistry washed down with Chardonnay. The ordinary citizens, thank goodness, still adhere to absolutes.... It is they who have saved the republic from creeping degradation while their 'betters' were derelict. Charles Dickens
class homicide one-thing
When one thing takes another away, what do we call that?” she asked my class. “Homicide!” I called out Chris Colfer
class two people
There are two distinctive classes of people today, those who have personal computers, and those who have several thousand extra dollars apiece. Dave Barry
class people behaviour
Whatever people may say, the fastidious formal manner of the upper classes is preferable to the slovenly easygoing behaviour of the common middle class. In moments of crisis, the former know how to act, the latter become uncouth brutes. Cesare Pavese
class black why-not
Why not exploit, enslave, or exterminate a class that everybody is taught to regard as inferior? Carter G. Woodson
class white benefits
I regard affirmative action as pernicious-a system that had wonderful ideals when it started but was almost immediately abused for the benefit of white middle-class women. Camille Paglia
classes field forth retiring talked together took trips
We were back and forth together and our classes took field trips together. We've even talked about retiring together. Debbie Miller
classes house people reminded talk talked time whenever
Whenever she's around you're pretty much happy. She'd come over to my house between classes and I'd take her to class. We'd just talk. I told her all the time she reminded me of my sister. There aren't many people I could talk to like I talked to her. Adam Carr
classes found meetings practice rolling schedules stones
We found out why the Rolling Stones don't have a day job. Meetings and classes and conflicting schedules chews up a lot of practice time. John Sherry
classes taken
Yes, and we've already taken all the classes and shots. Dixie Aiazzi
classes compete couple difficult events field focus home individual majority monday night prepared saturday stay team travel
We're just going to focus on individual events this weekend. The majority of the team will travel home Saturday night after the individual events, while a couple of the field event competitors will stay to compete Sunday. It makes it difficult to compete in the relays on Sunday, travel home and be prepared for classes Monday morning. Robert Ford
classes good learned people university
I worry that people think you have to go to a university to be a good writer, which is categorically untrue. I don't think I learned how to write at Oxford. I did not go to any creative writing classes or anything. Samantha Shannon
classes glad living strange teach telling
I don't teach writing classes anymore, and I'm really glad I don't, because I would feel very strange about telling people, 'Go out there and be a writer, and make a living from it.' Ursula K. Le Guin
classes demands full meet move system
We had been at full capacity. Now we could unfreeze the system and move classes around to better meet demands on the campuses. Michael Beals
classes demands full meet move system
We had been at full capacity, ... Now we could unfreeze the system and move classes around to better meet demands on the campuses. Michael Beals
enjoy
He that sympathizes in all the happiness of others, perhaps himself enjoys the safest happiness. Charles Caleb Colton
enjoy-life enjoy
I'm usually just enjoying life. Alan Jackson
enjoy higher feels
I feel that as much as I enjoy loafing, there is something higher for which to live. David McCullough
enjoy ifs
If you are in business, you are not enjoying. You are working. Carlos Slim
enjoyed films money scrap
I have enjoyed writing my own stuff, and it's been a privilege to be able to scrap some money together to be able to make films from my own scripts. Lisa Cholodenko
enjoyable guides hold maps memories offer people plan proud time variety wide
We are proud to be able to offer such a wide variety of maps and guides for people to plan their visit, as well as souvenirs that hold memories of the enjoyable time they had. Ruth Coleman
enjoying experience indoors relax scenery television
We're in a lodge. We're not in a tent. It's a way to relax at night. A little television indoors doesn't take away from my experience enjoying the scenery here. Rick Reynolds
enjoy open people secretly theater whenever
Whenever I open a movie, I go secretly to the theater and stand in the back and enjoy the moment. I laugh when people laugh, and when people cry, I laugh. Lee Byung-hun
enjoyment far job
Don't make career choices on short-term financial gain. Job satisfaction and career enjoyment are far more important. Henry Samueli
feelings age done
We all have some experience of a feeling, that comes over us occasionally, of what we are saying and doing having been said and done before, in a remote time - of our having been surrounded, dim ages ago, by the same faces, objects, and circumstances. Charles Dickens
feelings words-of-wisdom deeds
"O, Mrs. Clennam, Mrs. Clennam," said Little Dorrit, "angry feelings and unforgiving deeds are no comfort and no guide to you and me." Charles Dickens
feelings words-of-wisdom matter
It is, as Mr. Rokesmith says, a matter of feeling, but Lor how many matters ARE matters of feeling! Charles Dickens
feelings certain
In a certain sense, Zen is feeling life instead of feeling something about life. Alan Watts
feelings want cop
It's a great feeling to know that 100 cops want to stop you doing something and they can't. Alain Robert
feelings knows statues
I'm delighted. I don't know of anybody who had a statue built of them while they were living. It's a great feeling. Al Lopez
feelings dazzle christ
Christ dazzles me and stirs within me such feelings of amazement that I can never get over Him. Aiden Wilson Tozer
feeling-down red-lipstick feelings
If I'm feeling down in the dumps, or like I need a pop of colour, I'll put on MAC's Lipstick in Lady Danger. I discovered red lipstick when I did the Oscar season: Chanel sent me one and I realised how classic and glamorous it can be. Chloe Sevigny
feelings way roles
I like to disappear into a role. I equate the success of it with a feeling of being chemically changed. That's the only way I can express it. Chiwetel Ejiofor
starting
I like starting. It's pretty cool. Al Leiter
starting-out starting hard
It must be really hard to be starting out in music now. Bryan Ferry
start sweep top
When you sweep the stairs, you start at the top German Proverb
start
When you start to see cancellations, you really get worried. David Seiders
start
When you start to know what you're doing and why you're doing it, it makes it better. George White
start subjective talking uniform
When you start talking about prospects, it's a very subjective term. The way I look at it is as long as you've got a uniform on, you've got a chance. Grady Fuson
starting-over kindergarten wells
We'd all do well to start over again, preferably with kindergarten. Kurt Vonnegut
starting-over teapots starting
Originally I planned on starting a teapot collection. I really like them. Billy Dee Williams
starting-over finding-yourself world
I ain't never found no place for me to fit. Seem like all I do is start over. It ain't nothing to find no starting place in the world. You just start from where you find yourself. August Wilson