Linus Pauling

Linus Pauling
Linus Carl Pauling was an American chemist, biochemist, peace activist, author, and educator. He published more than 1,200 papers and books, of which about 850 dealt with scientific topics. New Scientist called him one of the 20 greatest scientists of all time, and as of 2000, he was rated the 16th most important scientist in history. Pauling was one of the founders of the fields of quantum chemistry and molecular biology...
NationalityAmerican
ProfessionScientist
Date of Birth28 February 1901
CityPortland, OR
CountryUnited States of America
I think that the formation of [DNA's] structure by Watson and Crick may turn out to be the greatest developments in the field of molecular genetics in recent years.
The McCarthy period came along...and many of the other scientists who had been working on these same lines gave up. Probably saying "Why should I sacrifice myself? I am a scientist, I am supposed to be working on scientific things, so I don't need to put myself at risk by talking about these possibilities." And I have said that perhaps I'm just stubborn... I have said "I don't like anybody to tell me what to do or to think, except Mrs. Pauling."
During the time that [Karl] Landsteiner gave me an education in the field of imununology, I discovered that he and I were thinking about the serologic problem in very different ways. He would ask, What do these experiments force us to believe about the nature of the world? I would ask, What is the most. simple and general picture of the world that we can formulate that is not ruled by these experiments? I realized that medical and biological investigators were not attacking their problems the same way that theoretical physicists do, the way I had been in the habit of doing.
Man's great power of thinking, remembering, and communicating are responsible for the evolution of civilization.
I think every person should be able to enjoy life. Try to decide what you most enjoy doing, and then look around to see if there is a job for which you could prepare yourself that would enable you to continue having this sort of joy.
When an old and distinguished person speaks to you, listen to him carefully and with respect — but do not believe him. Never put your trust into anything but your own intellect. Your elder, no matter whether he has gray hair or has lost his hair, no matter whether he is a Nobel laureate — may be wrong. The world progresses, year by year, century by century, as the members of the younger generation find out what was wrong among the things that their elders said. So you must always be skeptical — always think for yourself.
I believe that you can, by taking some simple and inexpensive measures, lead a longer life and extend your years of well-being. My most important recommendation is that you take vitamins every day in optimum amounts to supplement the vitamins that you receive in your food.
In teaching, you do not want to COVER things, you want to UNCOVER them. The best way to get good ideas is to have lots of ideas.
It was obvious-to me at any rate-that the answer was to why an enzyme is able to speed up a chemical reaction by as much as 10 million times. It had to do this by lowering the energy of activation-the energy of forming the activated complex. It could do this by forming strong bonds with the activated complex, but only weak bonds with the reactants or products.
An amino acid residue (other than glycine) has no symmetry elements. The general operation of conversion of one residue of a single chain into a second residue equivalent to the first is accordingly a rotation about an axis accompanied by translation along the axis. Hence the only configurations for a chain compatible with our postulate of equivalence of the residues are helical configurations.
I believe that you can, by taking some simple and inexpensive measures, extend your life and your years of well-being. My most important recommendation is that you take vitamins every day in optimun amounts, to supplement the vitamins you receive in your food.
...It would be possible to make much more progress than has been made if the NCI knew its job better, knew how to make discoveries...The NCI really does not know how to make discoveries....So long as the NCI is not willing to follow up ideas that seem good to people who have had experience making discoveries, the work of the NCI is going to be pedestrian.
..The truly fraudulent claims must be discarded. But novel methods of therapy should not be rejected because they are novel, or because they run counter to some generally accepted belief ("which may just be biased"), or because we do not understand the mechanism of the proposed treatment, or because it has come from an unconventional source.
It has been recognized that hydrogen bonds restrain protein molecules to their native configurations, and I believe that as the methods of structural chemistry are further applied to physiological problems it will be found that the significance of the hydrogen bond for physiology is greater than that of any other single structural feature.