Anthony Fauci
Anthony Fauci
Anthony Stephen "Tony" Fauciis an American immunologist who has made substantial contributions to HIV/AIDS research and other immunodeficiencies, both as a scientist and as the head of the National Institute of Allergy and Infectious Diseases...
NationalityAmerican
ProfessionScientist
Date of Birth24 December 1940
CountryUnited States of America
came fact hoped line percent response
We hoped to see a 75 percent response rate, but the fact it came in at 50 percent is not way out of line for our expectations.
direct elicit factor guarantee identify particular protecting response vaccine
If we could identify what that factor is -- and there's no guarantee we will, but if we can -- then one could direct your vaccine to elicit a response of that particular factor that is protecting them.
both contain elements immune itself presenting recognizes response system ultimately
When you vaccinate someone, or when you get infected, the microbe is presenting itself to the immune system in a way that the immune system recognizes the important elements of the microbe and makes an immune response, both an antibody response and a cellular response, to ultimately contain the microbe.
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Historically, a live vaccine induces more potent, lasting and broader immune responses than a killed vaccine. The body is seeing the microbe in a way that is much more analogous to a real infection.
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The entire purpose of a vaccine is to mimic infection as best you can. Historically, a live vaccine induces more potent, lasting and broader immune responses than a killed vaccine. The body is seeing the microbe in a way that is much more analogous to a real infection.
came diminished hidden levels pool three virus weeks within
Even in individuals in which we diminished the pool of the reservoir, the hidden reservoir, to levels that were essentially non-detectable ... the virus came right back within two to three weeks in essentially everyone.
available currently eliminate eradicate given virus
It does tell us is that given the currently available regimens that we have of anti-viral drugs that we are not going to eliminate or eradicate the virus from individuals,
true
We have to see if it is true and if we can do anything about it,
course early
We now know that these reservoirs are established very early in the course of infection.
albeit good high immune news spur vaccine
We have a vaccine we know can spur an immune response, albeit at very high doses. We're going in the right direction. The sobering news is we have a long way to go. So it's muted good news.
alter blunt burst course early enormous initial prevent production virus
Vaccines, if they can blunt that initial, enormous burst of virus production early on, even if it doesn't prevent initial infection, may dramatically alter the course of infection,
both private resulted today vaccines
Many vaccines in use today resulted from both government-sponsored and private research.
aids church combat community coordinate efforts epidemic local national research simply united
Simply put, to end the AIDS epidemic in the United States, we need to mobilize efforts in all our communities to combat HIV/AIDS and to coordinate these initiatives with research institutions, pharmaceutical companies, national organizations and local community and church groups.
assume entirely general horrendous moderate prepare public worst
You have to prepare for the worst, but it's entirely conceivable that we could have a moderate one. You have to prepare for a horrendous problem, but the general public shouldn't assume that we're going to see the worst case.