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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
attend basically bond couple definitely formed grew grown guys past people respect respecting throughout treating
The people who did attend are basically people we've grown to know very well over the past couple of years. Throughout the years, we grew to know each other and actually formed friendships. I also grew to respect those guys basically for respecting me and treating me like one of the guys. A bond was definitely formed. Misty Haven
attendance compete confirm delighted enable exciting extremely fans full hard mans next pleased racing reception secure series warm
We are pleased to confirm our attendance of the next two American Le Mans Series races. At the moment, we are working extremely hard to secure the sponsorship to enable us to compete in the full series and we have some very exciting partnerships under discussion. As always, we are delighted to be back in the US where the fans give us a warm reception and the racing is well-promoted. James Turner
attending people three year
We started three years ago with 150 people attending the event. This year we had more than 400. Paula Carney
attending came nobel opportunity unusual war
Because Ernest Lawrence's award came in the war years, I had the unusual opportunity of attending his Nobel Prize presentation ceremony. Luis Walter Alvarez
attend bigger great hope response spring wanting year
We always have a great response from vendors wanting to attend Spring Fling. We hope this year will be bigger and better than ever. Amanda Miller
attended demands executing intention
We have no intention of executing them ever and will only keep them for as long as our demands are not attended to. Jomo Gbomo
attend busy event people public recognize schedules
We want everyone to attend at least one event during those 10 days. But we also recognize people have busy schedules or they may not want to come to a public event but could get online. Karen Minkel
attended eighty fear great hundred number passage upwards
We fear our passage will be attended with difficulties by reason of the great number of passingers which are one hundred and eighty and upwards in number. Nathaniel Smith
attendance efficient
We've become a lot more efficient in documenting enrollment and attendance over the years. We think it's working well now. E. O. Wilson
college honor problem
Helen Keller was blind and deaf when she graduated from college with honors. So what's your problem? Charles Stanley
college silence black
My first college roommate greeted me with a shocked silence followed by, 'So. . .you're black. Al Roker
college years expected
I never expected to leave college early-especially after just one year. Chris Bosh
college thinking feelings
You think you're grown in college but you're not, because everything is kind of controlled. You lose the camaraderie and suddenly find yourself alone in an apartment just feeling lost. Chris Bosh
college class theater
When I entered college, I wasn't sure what I was going to do. My advisor happened to be from the theater department, and he encouraged me to take some classes there, which I did. David Selby
college what-matters more-time
Your education never stops and college is just the beginning. You come out of college with a huge advantage in that you've ideally and more times than not you've come out with a love of learning and that's what matters above all. David McCullough
college punishment liable
I didn't really escape that gravity until I moved 300 miles south to go to college at 18, where authorship no longer seemed something liable to induce vengeful punishment. David Knopfler
college long together
We essentially spent our college years together [with Seth Rogen and Evan Goldberg], so those were the kind of lasting friendships and the bond you form during those years, and those friendships last a really long time. David Krumholtz
college favorites-things journalism
My favorite thing is still journalism. I'm almost 50. This has been my life ever since I was in college. David Talbot
design soul secrecy
Secrecy is the soul of all great designs. Charles Caleb Colton
design soul enemy
Secrecy is the soul of all great designs. Perhaps more has been effected by concealing our own intentions than by discovering those of our enemy. Charles Caleb Colton
design paper answers
Just how do I design if not with prototyping? An excellent question. The short answer is 'on paper.' Alan Cooper
design products
Define what the product will do before you design how the product will do it. Alan Cooper
design simplicity lasts
Design principle: Take things away until the design breaks, then put that last thing back in. Alan Cooper
design want helpful
If we want users to like our software we should design it to behave like a likeable person: respectful, generous and helpful. Alan Cooper
design purpose littles
Everything God does has purpose and intention behind that design. It is a master design, and every little thing has its proper place and function. Aiden Wilson Tozer
design hitchhiking lasts
When is the last time you saw a Lamborghini sale? Chris Campbell
design planning form
Design is, literally, purposeful planning. Graphic Design, then, is the form those plans will take. Chip Kidd
dozens employers four mainly offenders report sex states talking
We are talking dozens and dozens of sex offenders - mainly from just four states that report the employers names. Phil Williams
dozens expensive pairs
I lost dozens of pairs of expensive glasses because I'd put them down and then not be able to find them again. Bonnie Tyler
dozens literary nature rather second
I've summarized dozens of books in my literary career; it's become rather second nature. Rick Perlstein
dozens teams using
A company like Adobe, there are dozens of different teams that are using Slack. Each of those elected to use Slack independently. Stewart Butterfield
dozens managing ways
There are dozens of ways one can go about managing his or her career, John Cross
dozens few foreign maybe
maybe there will be a need for a few dozens of foreign observers. Ehud Barak
dozens leads numerous people
Numerous people were interviewed and dozens of leads were investigated, John Montgomery
dozens freddy latino leaders-and-leadership literally proud support
Freddy Ferrer is proud to have the support of literally dozens of Latino leaders. Jen Bluestein
dozens met opportunity
I met dozens of pilots and would go on dates. I had the opportunity to go up in one of the planes, but I was scared of flying. Florence Green
ensure help whether
Whether it will be a success, I do not know. But I want to help ensure it works, Gerhard Schroeder
ensure markets security
When we find new markets for our harvest, we ensure the security of our state's economy, Tom Vilsack
ensure
You may succeed in your policy and ensure your own damnation, by your victory. James Larkin
ensure growth increase lives rural stable urban
Ultimately, stable growth will ensure that urban and rural incomes increase and people's lives improve. Li Keqiang
ensures exercising improves levels morning time
Exercising first thing in the morning ensures that you'll have the time for it, and it improves your self-control and energy levels all day long. Travis Bradberry
ensure pope visit
The pope is our guest. ... We will do everything to the hilt to ensure that the visit will be historic, Fidel Castro
ensures frame freedom guarantee happiness hopeful individual laws maximum minimal social
To guarantee the individual maximum freedom within a social frame of minimal laws ensures - if not happiness - its hopeful pursuit. John Updike
ensure fidelity smooth
Fidelity does have a succession plan in place to ensure a smooth transition. Edward Johnson, III
ensure needed receive
It is not enough to receive support, no matter, how needed it may be. It is fundamental to know how to receive this support and ensure that its result is exponential. Kay Rala Xanana Gusmao
freshman good leadership potential quite role seems since stepped taken time waiting year
When (Foster) was a freshman she had a good year and we've been waiting since that time for her to play up to her potential and this seems to be the year. She's taken on a leadership role with our team. It wasn't quite expected, but she's stepped into the role. Terri Cash
freshman nobody stand
When he got a rebound, nobody was going to take it away from him. For a freshman to go in and make that kind of a stand is very significant. Jim Calhoun
freshman home living period stay
When I was a freshman living in the dorms I went home a lot, but now that I live off-campus I really can't stay home for a long period of time. Desarae Garland
freshman game
Man, did the freshman come through with the game on the line. Will McKinney
freshman kids people saw three time trying younger
We're just trying new stuff. You've got to make some changes, give the young kids a chance. You saw three sophomores and a freshman out there tonight. Some of the younger kids put in a lot of time during the summer. We're shuffling people in. It's tough. Mike Wheeler
freshman great phenomenal win
She did phenomenal for anyone, but for a freshman to come in and ... win those is a great accomplishment. Tanya Chaplin
freshman seventh since three
She's a freshman with three years' experience. We've had her since seventh grade. Al Peacock
freshman good played
She played really well. That's a really good freshman they have. Jim Click
freshman letter
She lettered as a freshman, and not that many freshman letter for me. Mark LaTurner
graduates high school teaching
We don't have high school graduates teaching our kids. Ivy Lee
graduates school
I have been out of drama school for 13 years, so there are 13 years' worth of graduates behind me. Samuel Barnett
graduates collagen
I'll never graduate from collagen. Dolly Parton
graduates life-is this-life
This life is just your schooling for what you have to do when you graduate. David Berg
graduates ground hit
That allows our graduates to hit the ground running. Jim Davis
graduates might sending
You're sending out graduates who might not be industry-ready. Eric Shelton
graduates past star usa work year
This past year over 300 graduates went to work for P.A.M. Trucking, ... Over 300 graduates went to work for USA Trucking and over 100 went to work for Star Transportation. Larry Williams
graduates record second women
I second the motion. His record is spotless. He graduates every kid. He doesn't look at other women. He doesn't smoke. John Calipari
graduates helping high jackson middle school side west
It's Stonewall Jackson High School graduates helping the middle school. We want to help the middle school and help the West Side become the ?best side' again. Ralph Holmes
graphic million none noticed
When we got it back from the graphic artists, none of us noticed that it made it a million million. Paula Otto
graphics terrible time
'Grease' is an awesome movie. I wish they'd make a new one, more for our time. The graphics are terrible when you look back on it. Kyrie Irving
graphic
I was at Ground Zero, and it was, to me, such a graphic illustration of what terrorism has done to our world. Gloria Macapagal-Arroyo
graphic novels time
One of my favorite graphic novels of all time is Grant Morrison's 'Earth-2.' Roberto Aguirre-Sacasa
graphic unpleasant
I had one or two unpleasant occurrences. I don't need to get any more graphic than that. Scot Roskelley
graphic york
He was the most sought-after graphic illustrator in New York City. He was making $150,000 a year, which is like a half-million now. Thomas Sokolowski
graphics key
The graphics are very good, better than a lot of simulators. The avionics is what the key is. They're real avionics. Dave Kinney
graphic innovative novel press risk small willing
Long before 'Diary of a Wimpy Kid', 'Dork Diaries', and the graphic novel explosion, only a small press like Tricycle was willing to take a risk on such an innovative format. Marissa Moss
graphic novels
You know, I read graphic novels but not encyclopedically. Aisha Tyler
higher fewer
The higher you go, the fewer women there are. Chimamanda Ngozi Adichie
higher
The higher up I went, the less happy I was. Dave Chappelle
high junior played president schools york
I was president of the schools in junior high and high school, got a scholarship to New York University, played a little basketball, and was a celebrity. Louis Gossett, Jr.
highly regarding requests side
The other side has not responded to any of our requests regarding the abduction issue, so it is highly regrettable. Shinzo Abe
high potential profits
The potential profits are so high there's a win-at-any-cost mentality. James Browning
high models perception prices support
The perception is that it's too high end, too futuristic, but I think we will see prices and use models to support it. Mark Thompson
highest income leave north pay people simply tax
The people who pay the highest income tax are also the most mobile. They simply leave North Carolina. John Connaughton
high trying unique yorkers
We are always trying to look for unique ideas, and we wanted something new for New York. We thought that hey, it's an island, let's do something on the water...New Yorkers have pretty high expectations. John Remington
high large previous risk state
We've always been on a high state of alert. The perpetrators of the previous bombings are still very much at large and the risk is still very much with us, Marty Natalegawa
offering flames wind
Without the Spirit of God we can do nothing. We are as ships without wind or chariots without steeds. Like branches without sap, we are withered. Like coals without fire, we are useless. As an offering without the sacrificial flame, we are unaccepted. Charles Spurgeon
offering errors judging
Save me from the error of judging a church by its size, popularity or the amount of its yearly offerings. Aiden Wilson Tozer
offering giving offering-to-god
We ought not to be looking for a place to hide, but a place to give ourselves as an offering to God. Aiden Wilson Tozer
offering care return
By offering individuals ownership and control of their health care coverage, we return control to the patients; and that is exactly where it should be. Chris Chocola
offering media ideas
Being overseas at the time it all kind of happened was perfect because I had no idea that it was going to attract so much media attention and provoke these lovely people calling in and offering up their opinions and advice. Cathy Freeman
offer plane private response sea tigers
We are awaiting a response from the Tigers to an offer of a private sea plane for their use. Palitha Kohona
offering tickets
We started by offering tickets to evacuees in the Starkville motels. We thought we would give out about 200 or so. Larry Templeton
offering yankees guy
One of the best things about being a Yankee is that you have guys like Whitey Ford, Phil Rizzuto, Ron Guidry and Reggie Jackson wandering around the locker room offering you advice. Derek Jeter
offering perfect culture
No place is perfect, but I admire Oahu for its offering of the tropical and the urban, and then its Asian-inflected culture and cuisines. Chang-Rae Lee
programs send stay touch via whenever
We stay in touch pretty regularly, via e-mail or the phone. He'll send me programs and I'll tell him how I'm feeling. He'll give me paces and whenever we have the opportunity, we'll get together. Kevin Eastler
programs together
We were able to put together a packet of programs and get her into a house. Rod Williams
programs spent
We don't know if any of it's going to be funded at all, and if so, we don't know what programs it will be spent on, David Heil
programs sales
The programs were more about 'reallocating sales' than stimulating demand. Robert H. Connelly
programs together
The programs are coupled together by their funding. Jack Toney
programs students
We don't want to be adversarial but we see these programs that are adversarial to the students. Tim Vonville
programs support youth
There is a lot of support for youth programs here. Chris Mitchell
programs protect seniors sit
We as Republicans understand that we have got to protect these... entitlement programs - these entitlement programs for our seniors today. And we have to sit down and have a discussion. We need more ideas on the table. Eric Cantor
programs simply stopping view
Our view is that stopping their programs is simply something they have to do. Christopher Hill
school figures ifs
You can't figure out the Universe, especially if you're using figures to figure it. Alan Watts
school hard-work church
But perhaps when you were too obedient, and did not do openly what others did, and were quiet in church and hard-working at school, then some unknown rebellion brewed in you, doing harm to you, though how I do not understand. Alan Paton
school age taught
I've never studied anything formally. I was excluded from school at the age of 17, so I am an autodidact, which is a word that I have taught myself. Alan Moore
school opportunity thinking
I don’t think people realise how vital libraries are or what a colossal danger it would be if we were to lose any more. Having had a truncated school life myself, all of my education from the age of 17 has been self-taught. I wouldn’t be the person I am today if it wasn’t for the opportunities the library gave me. Alan Moore
school ideas forgotten
I've never forgotten that experience. But I had nobody at school that was either like Hector or Irwin. The masters had no idea what was expected of you in the scholarship exam, so you just had to busk it really. Alan Bennett
school boys oxford
My experience came before most of you were born. My school was a state school in Leeds and the headmaster usually sent students to Leeds University but he didn't normally send them to Oxford or Cambridge. But the headmaster happened to have been to Cambridge and decided to try and push some of us towards Oxford and Cambridge. So, half a dozen of us tried - not all of us in history - and we all eventually got in. So, to that extent, it [The History Boys] comes out of my own experience. Alan Bennett
school care students
I'm 53. I don't care about high school students. I find them irritating and uninformed. Alan Ball
school exercise keys
Musicals are hard for me because I got thrown out of the glee club in high school, because I couldn't sing in tune at the time. I can sing in tune now, but I have to work really hard on it to make sure that I don't exercise one of my great talents, which is the ability to sing in three keys at the same time. Alan Alda
school thinking lasts
When I studied how to think in school, I was taught that the first rule of logic was that a thing cannot both be and not be at the same time and in the same respect. That last note, “in the same respect,” says a lot. As soon as you change the frame of reference, you’ve changed the truthiness of a once immutable fact. Alan Alda
states secretary
I loved what I did. I could've been secretary of state for ever. Madeleine Albright
states evident secretary
I loved being Secretary of State, that's probably evident to everyone who watched me. Madeleine Albright
states barometer interest
...interest is the barometer of the state... David Hume
states hyperbole constant
I live in a constant state of hyperbole. Eden Sher
states senators productive
I was very productive as a senator for my state. Carol Moseley Braun
state
We wrestled better than we did in the first. We got after the guys, and they wanted to get to the state final. Clifford Garnto
state
to play in the state in which they're franchised. Paul Tagliabue
state
We're realists. We know we're in a state where the Legislature is anti-choice. Susan Hill
state systems whether
When the state inspectors look at us, they will see that the systems are in place. You have to have a system whether you have one person or 100. Al Mollozzi
tennessee persons loops
Part of it is living in Tennessee. I'm so out of the loop. And as a person, I'm out of the loop. I'm oblivious by nature. Ann Patchett
tennessee helping vulnerable
Tennessee helps me open up. I'm much more vulnerable there, more willing to talk about anything. Dan Fogelberg
tennessee georgia hillbilly
Tennessee's a hillbilly dumping ground, and Georgia's a lousy state too. Flannery O'Connor
tennessee littles rooms
I don't know of any wrestler who hasn't, at one time or another, been with a fan. One time I met a woman at a match in Tennessee, and afterward we went to a little roadside motel. We checked in, went to the room, and enjoyed each other for an hour or so. Jerry Lawler
tennessee conservative american-politics
In Washington I'm thought of as a conservative, but in Tennessee I'm thought of as a Bolshevik. Howard Baker
tennessee
If you want to read about some full-blown fights, read about the Tennessee players, not our guys. Steve Spurrier
tennessee east grew
I grew up in east Tennessee, and everybody knew everybody's business. Kenny Chesney
tennessee shy pot
Dolly Parton made me chicken and dumplings. That Tennessee woman can burn some pots! And we know that I am not necessarily shy to a fork! Queen Latifah
training felt
I loved being back out on the pitch. Although I have not been in full training, I felt pretty good. David Ginola
training stardom
I've been in training for stardom. Bernie Mac
training mind taught
I didn't mind basic training. It taught me that something that seems impossible at the start can be achieved. Arnold Schwarzenegger
training adore hard
I simply adore the exhaustion that comes with training hard. Deena Kastor
training boeing film
I always liked show biz and got to make a few training films at Boeing. Bill Nye
training mind spirit
The word liberal distinguishes whatever nourishes the mind and spirit from the training which is merely practical or professional or from the trivialities which are no training at all. Alan K. Simpson
training java degrees
I fear - as far as I can tell - that most undergraduate degrees in computer science these days are basically Java vocational training. Alan Kay
training benefits enough
You benefit from getting in enough volume at the beginning of your training. Bernard Lagat
training age trying
We've been trying to sell cyclists of all ages and abilities on very detailed and demanding education and training programs designed to make them more like motorists. Bicyclists have shown they don't want this. What cyclists repeatedly tell us they do want is more safe places to ride, and it is time we listened to that message. Bill Wilkinson
ways
We know we have a long ways to go with the Missoula public. David Blair
ways work
There are lots of ways to work together. Jacob Lew
ways
Entrepreneurs are like visionaries. One of the ways they run forward is by viewing the thing they're doing as something that's going to be the whole world. Reid Hoffman
ways
There are ways to get around that, though. Colin Devine
ways
I've learned to create a palette, a vocabulary of ways to take pictures. Annie Leibovitz
ways
I study the ways new media shapes people's perceptions of the world. Ethan Zuckerman
ways
There are other ways to get up there to get him. Phil Savage
ways
We can create new ways to create clean water. Craig Venter
ways
There's not a lot of original ways to get attention in the press. Emma Roberts