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advance benefit cells directly five goal huge illnesses known patients potential progress recently results stem towards ultimate using variety widely
The potential of stem cells has been widely known for many years, but it is only recently we have started to make progress towards the ultimate goal of using them in patients. These results show it may be as little as five years before this advance can be used to directly benefit patients for a huge variety of illnesses and injuries. Anne Bishop
advance believe congress convince core perception value voters work
The perception by the core value voters is that Congress has not done enough to advance their core issues. We believe they have been at work, but there is more work to be done to convince their constituencies. Tony Perkins
advance appreciate gotten help support thank
We appreciate all the help we have gotten so far. Without the support of the community, we wouldn't have the school. We want to thank everyone in advance for everything done. Jo Brown
advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advance clinical company eventual experience extensive manage partner pleased rapidly required technology
We are pleased to partner with a company with the extensive cardiovascular experience required to rapidly advance our technology through the clinical development and regulatory process, and manage the eventual manufacturing and commercialization. Robert Harris
advances agreement businesses company enter exit focus growth mature pleased reputation sale strategy
We are pleased to enter into the agreement with Nekoosa Coated Products, a company with a well-earned reputation in the industry. Also, the sale advances Nashua's strategy to exit non-strategic and mature businesses and focus on growth opportunities. Andrew Albert
advance conference easy fall girls ncaa rattled season straight stuck tournament wins
We started the season 5-5 and it would have been easy to fall off. The girls stuck with it, and we rattled off 14 straight wins at one point. Getting back to the conference championship and making the NCAA tournament is pretty important to our players. Hopefully, we will advance and do well. Dee Bell
advances believe imminent item law near pricing recent require
We believe that recent and imminent technological advances will require a modernization of the item pricing law in the near future. John Simley
advances deaths direct everyday seeing
We are seeing advances everyday and deaths are decreasing. It is a direct correlation. Jan Ulmer
bats couple kids looking slow took turn
We started slow tonight. It took our bats a while to get going, but now I'm looking down the lineup and a couple kids went 3-for-4, so it didn't turn out too bad. Bill Fetters
bats slow
We started off slow but our bats started to come around after the first inning. Chris Jones
bats beating expect films guy others people saying swinging
I did 'Kidulthood' and 'Adulthood,' and that's what people wanted and expect me to always do. They want me to do 'hood films and be the guy swinging baseball bats and saying 'Yo Blood' and beating up others in the street. Noel Clarke
bats good hitters pitchers swing tough
When you swing the bats like that, you're going to be pretty tough to beat. It was a good day. The hitters did a good job. It wasn't like their pitchers were slopping it up there. Craig Nicholson
bats boys couple easy game hit kids knock needed swinging unselfish walks
We accomplished what we needed to. We're really swinging the bats right now and a lot of kids had unselfish at-bats when the game was still tight. We had some walks and a couple of kids got hit and then the big boys knock them in. We just don't have an easy out in the lineup. Vance Arnold
bats
I've got a right to knock down anybody holding a bat. Early Wynn
bats break process
The biggest thing that I came across, right off the bat, was that you can't shoot this like a regular movie with multiple takes. You have to, because it's such a protracted process, break it down to the frame and pretty much get one shot. Charlie Kaufman
bats believe starting taken time
We're starting to believe a little bit. We're starting to believe in our bats a little bit, and it's taken a long time to get there. That's big for us. Dave Esquer
bats games light playing swing tired
We're going to swing the bats and hit, but I'm tired of playing well enough to win and not winning. We're 16 games into the season. The light should be going on and we should be making plays. Dennis Phillips
fed
We started off sluggish. But we fed off our fans. Trot Nixon
federal-reserve
From now on, depressions will be scientifically created. Charles Lindbergh
feds fed-up
I'm fed up with being bossed around. David Hockney
fed seen softer stay tone
We have seen a softer tone in their write-ups. I think there is a real sense that the Fed is going to stay on the sidelines. Diane Swonk
federal government increase
We have seen an outrageous increase in the size, scope, and intrusiveness of the federal government. Jason Chaffetz
federal government
We have no idea. We will never know, because so much being done by the federal government now is shrouded in secrecy. Fran Quigley
fed heck horse job kid liked nail pitches threw
When your horse is out there and pitches his butt off, my job is to nail it down, ... We would've liked to have fed off Jake's energy. The kid threw the heck out of the ball. Trevor Hoffman
federal history state supported
We're making history again. Never before have we supported so many state and federal missions. J. Horton
federal meeting next remain reserve stimulus underlying vacuum week
We remain in a stimulus vacuum and the underlying motif this week will be the Federal Reserve meeting next week. Larry Wachtel
few-words speak adages
With few words, one can speak the truth. Bryan Adams
fewer
Much better to do fewer things and have time to make the most of them. Carl Honore
few liked love properly sure
I don't think I've ever properly been in love. I've had a few girlfriends and have liked them loads, but I'm not sure it was love. Luke Pasqualino
few helping hit move next plugging series work
Those three years on 'Loving' were instrumental in helping me move through the next few years of work, where it was hit or miss. I was on series that would get canceled, then I would be a movie that wouldn't come out or do as well as I hoped. You learn that you have to just keep plugging away and never take anything for granted. Michael Weatherly
few gave intrigued khan money next politics registered sure titles typical
I have registered few titles like 'Bharat Bandh,' 'Calendar Girl,' 'Money Politics.' The titles just intrigued me, so I registered. I had a title, 'Jai Ho,' which I gave to Sohail Khan for his next film with Salman Khan. These are typical Madhur Bhandarkar kind of films. I may make a film or not on such titles... not sure yet. Madhur Bhandarkar
few matter mean minutes stopped
We stopped doing what we were doing and we let them right back in the game. Then we're tied. No matter what we did in the first few minutes it didn't mean anything. Tim DeBruycker
few learning players season
We started off the season making a few more turnovers than we would have liked, but a lot of that had to do with all the new players learning a new system. Joddie Gleason
few missed picked receive serve serves
We started a little slow, and we picked it up after the first loss. We didn't serve receive well, and we missed a few serves that were critical. That just comes with experience. Nancy Diers
few games needed played playoff stay
We started a few games where we started strong, experience-wise but we should have played better in the end. We needed this game to stay in the playoff hunt. Jamie Watson
fighting words-of-wisdom shadow
But injustice breeds injustice; the fighting with shadows and being defeated by them necessitates the setting up of substances to combat. Charles Dickens
fighting pay had-enough
Had enough of my poetry yet? That's why they pay me to fight demons instead. Charles Stross
fighting winning battle
Fight all your battles on your knees and you win every time. Charles Stanley
fighting errors evil
A church that does not exist to reclaim heathenism, to fight evil, to destroy error, to put down falsehood, a church that does not exist to take the side of the poor, to denounce injustice and to hold up righteousness, is a church that has no right to be. Not for yourself, O church, do you exist, any more than Christ existed for Himself. Charles Spurgeon
fighting decision soul
The petitions of Moses discomfited the enemy more than the fighting of Joshua. Yet both were needed. No, in the soul's conflict, force and fervor, decision and devotion, valour and vehemence, must join their forces, and all will be well. Charles Spurgeon
fighting iraq america
The promise of America is one immigration policy for all who seek to enter our shores, whether they come from Mexico, Haiti or Canada, there must be one set of rules for everybody. We cannot welcome those to come and then try and act as though any culture will not be respected or treated inferior. We cannot look at the Latino community and preach 'one language.' No one gave them an English test before they sent them to Iraq to fight for America. Al Sharpton
fighting people corporations
Sometimes you're fighting corporations and forget that people can talk to each other. Al Pacino
fighting night missing
I went into a restaurant one night and ordered lobster, and the waiter brought me one with a claw missing. I called him over and told him about it. He told me that in the back there's a tank they keep the lobsters in and while they're in there, they fight and sometimes one loses a claw. I told him 'then bring me a winner.' Al McGuire
fighting years careers
I was appointed United States attorney on September 10, 2001. And I spent the next seven years of my career fighting terrorism and putting terrorists in jail. Chris Christie
focused life lose rush
I was just so focused on being healthy for my baby during pregnancy, and afterward I was not in a rush to lose the weight. I really wanted to be as healthy as I could. It wasn't about getting my six-pack back. There are more important things in life than a six-pack, I realized. Marisa Miller
focused
I get pretty focused when I start working on something. And I drink a lot of water, way more than most people. Nick Woodman
focused hoping
We are very focused on hoping that these negotiations do succeed, Condoleezza Rice
focused game great home knew prove
When we were 1-6, all we focused on was that we were better than that. We knew it; we just had to prove it. We've come a long way and it's great to be back to .500 and to know we'll get a home game in the tournament. R. Ingram
focused remain student
We remain more student focused than anything else. That is what we try to do. Mike Milone
focused listen meet music sure twenty whatever
Usually I like to take a nap. I'm not sure (how it started). After a long day of school... Twenty minutes, that's about it. ... I listen to music to get focused and think about the meet or whatever it may be. Jake Peymann
focused fund helping hope improve industry innovative offering positive specific
We're more than just a supplier to the trucking industry. We have always focused on helping to improve the trucking industry by offering innovative solutions, and we feel the need to do more than business-as-usual in this case. By helping to fund this specific program, we hope to make a positive difference. Bill Greubel
focused improvement tough week
We're focused on this year's tough schedule. The SCIAC is really up this year. With the improvement in the league, it should be a dogfight week in and week out all the way to the end. Scott Squires
focused internet market today
We're focused on the Internet community. That market today is for PCs. Andrew Wright
huge portions seeing systems
We started seeing huge vulnerabilities. And portions of those systems were extraordinarily secure. But they were Maginot Lines. Scott Borg
huge three win
We still need to win three games. I feel like if we win those three games, there's going to be a huge celebration. Luis Rivera
huge opens player space
When you take a player off the ice, even if it is your own team, that opens space and can be a huge advantage, especially when you have a player like Allie. She is just so dynamic... one of those worth-the-price-of-admission kind of players. Bill Halbrehder
huge job realized written
I was a huge rereader, so I've read all the Chronicles of Narnia, at minimum, 13 times each. In reading that series, I realized that someone had written those books, and that was that person's job. And I thought, 'That is the job for me. That is the job I'm going to have when I grow up.' Lisa Papademetriou
hugely land sale weighs whether
Whether or not a land is for sale weighs in hugely for criteria. Paul Campbell
huge next weeks
We're so young in so many areas. These next two weeks will be huge for our development. Pete Carroll
huge
There's a huge latent market for software development that's just flat-out honest. Kent Beck
huge limited
With the limited monies we've got, we know it's going to show the need for a huge appropriation by the state. Harvey Jewett
huge musical people
I'm not a huge musical fan. It's like when people just jump out singing; it's not real. Keke Palmer
kids wells understood
Well, as a kid I did not get Shakespeare. I just never understood it. Alanis Morissette
kids winning
You'll never win anything with kids Alan Hansen
kids scientist natural
Kids are natural scientists. Alan Alda
kids mind desperate
In my own mind, I was sort of a desperate kid. Al Purdy
kids gang-members wife
Near my house in Los Angeles is a waterfall. I love to take the wife and kids, but it's also near a sketchy neighborhood. So there's a lot of gang members that hang out at the waterfall. It's like somebody took an Ansel Adams photo and then put a Cypress Hill video inside it. Al Madrigal
kids enjoyed
I went to all the Love-Ins. I took my kids. I enjoyed myself. Al Lewis
kids sure various
We want the kids to do as well as they can. There are so many opportunities (for various activities), and that's good. But, how do we make sure it's not a distraction. Brad Lancaster
kids years add
It doesn't matter how old I get, I always act like an excited five year-old kid with severe ADD and a waddle at Disneyland. Chris Colfer
kids awkward special
My life is an awkward visit from the kid's table while awaiting a History Channel special. Chris Colfer
next generations products
The next generation product almost never comes from the previous generation. Al Ries
next causes steps
I love to just go to the movies, watch movies, listen to the scores and all that 'cause that's, like, the next step for me. Akon
next
We want to see who we're going to keep around next season. Mike Butters
next want knows
I don't want to go bald, I don't know what's coming up next. Chris Cooper
next performances improving
Everything I do is geared towards improving my next performance. Carolina Kluft
next performance sequels stock store
The performance of the stock is going to come down to the movies. It's that simple. And there are no sequels in store for next year. David Miller
next percent spending total
We are making a dent, but we are not going to be at 10 percent of total spending by next year. Greg Stuart
next night parking spent until
We spent the night at a parking lot until the next morning. David Foster
next faces realization
In the face of impermanence, if your next thought is good, this is what we call the realization body. Bill Porter
played taken
We've already done that. The two quarterbacks we have, Vincent hasn't played before and Gill played JC. We've taken out as much as we can. Hal Mumme
played stopped ways
We stopped doing all the little things that we did earlier. We reverted back to some of our old ways and played with not a lot of intensity. Mike Pomerenke
played stood
We stood up to the challenge. We played very well. We did not play well enough to win. Dave Odom
played
We started a little slow, but we hadn't played any. Scooter Dunn
played since team time
We were a whole different team since the first time we played them. Indy Uhlenhopp
played teams
'Justified' is one of the greatest teams I've ever played for. It's just awesome. Neal McDonough
played
When we weren't in the box, I thought we played pretty well. Jeff Halpern
played proud starting
We're starting to come together. We played as a team, and I was very proud of them tonight. Travis Paquet
played prepared time
We're more prepared for it than the first time we played them. Jeff Perreault
player games profound
As in the game of billiards, the balls are constantly producing effects from mere chance, which the most skillful player could neither execute nor foresee, but which, when they do happen, serve mainly to teach him how much he has still to learn; so it is in the most profound and complicated game of politics and diplomacy. In both cases, we can only regulate our play by what we have seen, rather than by what we have hoped; and by what we have experienced, rather than by what we have expected. Charles Caleb Colton
player sight league
It's important that top clubs don't lose sight of the fact that it's the English Premier League and English players should be involved. Alan Pardew
player nhl cities
I played with Joey Mullen back in Salt Lake City before he got called up to St. Louis. He was the first player ever to score 20 goals in the American League and 20 in the NHL. I've kept in contact with him and he's a great guy. Alain Vigneault
player league different
All of a sudden I'm in the major leagues and we're traveling from town to town. I see the other players dressing different every day. I've got only one suit and I keep wearing it over and over. I'm really embarrassed. Al Kaline
player long stylist
In my opinion, Louis Armstrong is the greatest trumpet stylist of all time and has influenced every trumpet player of his time and long after Al Hirt
player thinking long
I think I earned the players' respect, and that's the ultimate in life, isn't it? I didn't care if they liked me or disliked me, as long as I had their respect. Al Barlick
player dictator guilty
Once again, as a flawed evaluator of dictators and failed strategist who has permitted Russia back in as a major player in the Middle East, is Hillary Clinton guilty or not guilty? Chris Christie
player trying being-the-best
I'm just trying to be the best player that I can be. Chris Bosh
player games watches
When you're not in the game, you can watch. Certain players have mannerisms, and they do the same things repetitiously. Chris Bosh
ready scout shares stand support
We stand ready to support any organization that shares Scout values. David Richardson
ready road run
I want to be an actor, and I am being an actor. I'm not ready to run off on a road trip. Yet. Liane Balaban
ready tough
We have to get ready now for Plainfield South. They are another scrappy, tough team. We'll have to be ready. Jeff Bambule
ready reasons
We have so many reasons to be here tonight. I'm also ready to do some shopping! Natalie Chanin
ready-to-die not-ready ifs
If you're not ready to die, then how can you live? Charles de Lint
ready
I was embarrased, horrified and absolutely ready to jump him! Charlaine Harris
ready worry
Tomorrow? We have to go there and do it, ... Don't worry, I'll be ready for tomorrow. Mariano Rivera
ready respond sitting
We're sitting there on go, ready to respond if we have to. Cliff Lusk
ready sitting ticking time town
We're sitting on a ticking time bomb. This town is ready to ignite. Larry Southard
runners tweak
We may tweak things a little bit. When we get runners on base, we have to get them around to score. We will do what ever it takes. Tom Woodruff
runners sports tainted took
If you look at the sponsors who were in the sport 15 years ago compared to now there are a lot fewer. Why? Because those runners who took drugs tainted the sport. They tainted all of us in it. Maurice Greene
runners
We had ample opportunities to score. We need to have better at-bats with runners on base. Donna Martin
runners runs score scoring
That's been the story of our year. We just can't score runs when we need to and get runs in when we've got runners in scoring position. Chris Bryant
runners sam
Sam pitched very well for us, we just have to get some of those runners to score. Andrew C. Bradley
runners
You never see a smiling runner. George Carlin
runners running
That's fine; we runners are, after all, up for a challenge. Bill Rodgers
runners second third
It's very frustrating. We had some opportunities, and we didn't get it done. I had runners on second and third with one out. You have to find a way to get it in. Nick Johnson
runners stride not-perfect
A runner's stride is not perfectly efficient. Nancy Gibbs
second-chance now-or-never next
Sometimes there is no next time, no time-outs, no second chances. Sometimes it’s now or never. Alan Bennett
second-chance giving leader
We're not willing to give black leaders second chances because, in most cases, we're not willing to give them first chances. Al Sharpton
second-chance kicking want
It certainly is gravy every day above ground right now, after kicking that heroin habit. I've been given a second chance in life, and I don't want to let a minute go by without enjoying it. Al Jourgensen
second-chance careers half
I really do see it as the start of the second half of my career. Al Jarreau
second-chance easy novel
Publishers love to compartmentalize, and Second Chance was not an easy novel to define. Chet Williamson
second-chance feels chances-in-life
There are no second chances in life, except to feel remorse. Carlos Ruiz Zafon
second-chance found has-beens
This has been my life. I have found it worth living, and would gladly live it again if the second chance were offered me. Bertrand Russell
second
We were better in the second game, so it's disappointing that we didn't play more relaxed. Nick Whaley
second-chance citizens rehabilitation
I am a firm believer that upon release, ex-offenders should be afforded a second chance to become productive citizens by providing rehabilitation and education that will help them join the workforce. Charles Rangel
shut-up showers capacity
I still sing every day - in the shower or on the set all day. I'm sure everyone will tell you that I never shut up. But it's not in the capacity that I would like to. Aaron Tveit
shut stable
When the steed is stolen, you shut the stable door. Spanish Proverb
shut-up one-thing
There's only one thing to say to the censors: Shut up. Chris Crutcher
shut
Shut up. Goodbye. Get off the phone, man. Michael Irvin
shuttle space station stay time
When I did my spacewalks, it was during space station construction. So the shuttle was docked to the fledgling ISS at the time. So we would always stay tethered. Chris Hadfield
shut
My advice to all interviewers is: Shut up and listen. It's harder than it sounds. Errol Morris
shut won
We still could have shut them out and won by four. Marty Schottenheimer
shut true
You look out there, ... and there aren't too many true aces out there that are going to shut you down. Jason Marquis
shut-up
There isn't much I have to say, that I wouldn't rather just shut up and do. Ani Difranco
strong jobs men
No two things differ more than hurry and dispatch. Hurry is the mark of a weak mind, dispatch of a strong one. A weak man in office, like a squirrel in a cage, is laboring eternally, but to no purpose, and is in constant motion without getting on a job; like a turnstile, he is in everybody's way, but stops nobody; he talks a great deal, but says very little; looks into everything but sees nothing; and has a hundred irons in the fire, but very few of them are hot, and with those few that are, he only burns his fingers. Charles Caleb Colton
strong mind haste
Hurry is the mark of a weak mind, dispatch of a strong one. Charles Caleb Colton
strong party reason
He that aspires to be the head of a party will find it more difficult to please his friends than to perplex his foes. He must often act from false reasons which are weak, because he dares not avow the true reasons which are strong. Charles Caleb Colton
strong hands monsters
The mob is a monster, with the hands of Briareus, but the head of Polyphemus,--strong to execute, but blind to perceive. Charles Caleb Colton
strong advice desire
When we feel a strong desire to thrust our advice upon others, it is usually because we suspect their weakness; but we ought rather to suspect our own. Charles Caleb Colton
strong passion may
Strong as our passions are, they may be starved into submission, and conquered without being killed. Charles Caleb Colton
strong men thinking
Men of strong minds and who think for themselves, should not be discouraged on finding occasionally that some of their best ideas have been anticipated by former writers; they will neither anathematize others nor despair themselves. They will rather go on discovering things before discovered, until they are rewarded with a land hitherto unknown, an empire indisputably their own, both right of conquest and of discovery. Charles Caleb Colton
strong circles errors
Unity of opinion is indeed a glorious and desirable thing, and its circle cannot be too strong and extended, if the centre be truth; but if the centre be error, the greater the circumference, the greater the evil. Charles Caleb Colton
strong two mind
No two things differ more than hurry and despatch. Hurry is the mark of a weak mind; despatch of a strong one. Charles Caleb Colton
tremendous
She's just a tremendous athlete. She can do it all. She's very versatile, and she can really play any position. Jim Gresh
tremendous
I think there's a tremendous amount of unacknowledged hostility in American culture. Chris Jordan
tremendous
There is a tremendous untapped marketplace here in Mexico. Michael Foley
tremendous
Mum was a tremendous Anglo-Catholic. Very impressive, actually. She made me go to church for years - I still don't want to because of that. Jane Gardam
tremendous wonderful
I had many, many wonderful conversations with her about everything under the sun. She was one tremendous person. Robert Matthews
tremendous
He's a tremendous defender. He does a lot for us back there. Russ Boyer
tremendous
He has a tremendous attitude. He's very optimistic. He's very positive. Lloyd Carr
tremendous
He's had a tremendous year, I'll tell you, Joel Quenneville
tremendous
We had a tremendous year. It's been dreamlike in many ways. Steve Coppell
winter darkness scrooge
Darkness is cheap, and Scrooge liked it. Charles Dickens
winter age lapland
Cheerfulness ought to be the viaticum vitae of their life to the old; age without cheerfulness is a Lapland winter without a sun. Charles Caleb Colton
winning race looks
If we look backwards to antiquity it should be as those that are winning a race. Charles Caleb Colton
wine order water
In order to try whether a vessel be leaky, we first prove it with water before we trust it with wine. Charles Caleb Colton
wings gone originality
All the poets are indebted more or less to those who have gone before them; even Homer's originality has been questioned, and Virgil owes almost as much to Theocritus, in his Pastorals, as to Homer, in his Heroics; and if our own countryman, Milton, has soared above both Homer and Virgil, it is because he has stolen some feathers from their wings. Charles Caleb Colton
wind literature wave
Commerce flourishes by circumstances, precarious, transitory, contingent, almost as the winds and waves that bring it to our shores. Charles Caleb Colton
wind fire tale-of-two-cities
Then tell Wind and Fire where to stop," returned madame; "but don't tell me. Charles Dickens
winning race obstacles
Ride on! Ride on over all obstacles and win the race. Charles Dickens
wine paris six
Along the Paris streets, the death-carts rumble, hollow and harsh. Six tumbrils carry the day's wine to La Guillotine. Charles Dickens