Claude Bernard

Claude Bernard
Claude Bernardwas a French physiologist. Historian Ierome Bernard Cohen of Harvard University called Bernard "one of the greatest of all men of science". Among many other accomplishments, he was one of the first to suggest the use of blind experiments to ensure the objectivity of scientific observations. He originated the term milieu intérieur, and the associated concept of homeostasis...
NationalityFrench
ProfessionScientist
Date of Birth12 July 1813
CityRhone, France
CountryFrance
Man can learn nothing except by going from the known to the unknown.
Observation is a passive science, experimentation an active science.
To be worthy of the name, an experimenter must be at once theorist and practitioner. While he must completely master the art of establishing experimental facts, which are the materials of science, he must also clearly understand the scientific principles which guide his reasoning through the varied experimental study of natural phenomena. We cannot separate these two things: head and hand. An able hand, without a head to direct it, is a blind tool; the head is powerless without its executive hand.
Laplace considers astronomy a science of observation, because we can only observe the movements of the planets; we cannot reach them, indeed, to alter their course and to experiment with them. "On earth," said Laplace, "we make phenomena vary by experiments; in the sky, we carefully define all the phenomena presented to us by celestial motion." Certain physicians call medicine a science of observations, because they wrongly think that experimentation is inapplicable to it.
The goal of scientific physicians in their own science ... is to reduce the indeterminate. Statistics therefore apply only to cases in which the cause of the facts observed is still indeterminate.
A man of science rises ever, in seeking truth; and if he never finds it in its wholeness, he discovers nevertheless very significant fragments; and these fragments of universal truth are precisely what constitutes science.
Theories are like a stairway; by climbing, science widens its horizon more and more, because theories embody and necessarily include proportionately more facts as they advance.
Well-observed facts, though brought to light by passing theories, will never die; they are the material on which alone the house of science will at last be built.
When a physician is called to a patient, he should decide on the diagnosis, then the prognosis, and then the treatment. ... Physicians must know the evolution of the disease, its duration and gravity in order to predict its course and outcome. Here statistics intervene to guide physicians, by teaching them the proportion of mortal cases, and if observation has also shown that the successful and unsuccessful cases can be recognized by certain signs, then the prognosis is more certain.
Ardent desire for knowledge, in fact, is the one motive attracting and supporting investigators in their efforts; and just this knowledge, really grasped and yet always flying before them, becomes at once their sole torment and their sole happiness. Those who do not know the torment of the unknown cannot have the joy of discovery which is certainly the liveliest that the mind of man can ever feel.
As soon as the circumstances of an experiment are well known, we stop gathering statistics. ... The effect will occur always without exception, because the cause of the phenomena is accurately defined. Only when a phenomenon includes conditions as yet undefined,Only when a phenomenon includes conditions as yet undefined, can we compile statistics. ... we must learn therefore that we compile statistics only when we cannot possibly help it; for in my opinion, statistics can never yield scientific truth.
Mediocre men often have the most acquired knowledge. It is in the darker. It is in the darker regions of science that great men are recognized; they are marked by ideas which light up phenomena hitherto obscure and carry science forward.
We must keep our freedom of mind, ... and must believe that in nature what is absurd, according to our theories, is not always impossible.
It has often been said that, to make discoveries, one must be ignorant. This opinion, mistaken in itself, nevertheless conceals a truth. It means that it is better to know nothing than to keep in mind fixed ideas based on theories whose confirmation we constantly seek, neglecting meanwhile everything that fails to agree with them.