Akhilesh Pandey
Akhilesh Pandey
alley based blind candidate conceptual develop finding genes genetic gold importance information involved mine number proteins roles seeking several specific using ways
Using HPRD and several other databases, we have been able to develop a gold mine of new information for researchers seeking new ways of finding candidate genes involved in genetic diseases. And our demonstration that a protein's importance is not based on the number of interactions it has with other proteins is an important conceptual breakthrough. It eliminates a blind alley that could mislead researchers investigating the roles of specific proteins in the cell.
companies using
Most pharmaceutical companies have approached us and many are using the data.
companies using
Many diagnostic companies have also inquired or are using this data.
based conceptual importance number proteins
Our demonstration that a proteins importance is not based on the number of interactions it has with other proteins is an important conceptual breakthrough.
blanks confirm eventually expect fill human laboratory linking proved
We proved they were valid. By linking computerized sleuthing to laboratory experiments to confirm those findings, we expect to be able to eventually fill in many blanks in human protein-protein interactions.
cells describing detailed disease health occur proteins study
It is the most detailed study yet describing the interplay of proteins that occur in cells during health and disease.
action blueprints genes human life proteins
Genes are the blueprints for proteins, but proteins are where the action is in human life and health.
ability action approach blueprints candidate disorders genes genetic human involved life links novel offers proteins rapidly sets
Genes are important because they are the blueprints for proteins, but proteins are where the action is in human life and health. This ability to find links between sets of proteins involved in different genetic disorders offers a novel approach for more rapidly identifying new candidate genes involved in human diseases.