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advance benefit cells directly five goal huge illnesses known patients potential progress recently results stem towards ultimate using variety widely
The potential of stem cells has been widely known for many years, but it is only recently we have started to make progress towards the ultimate goal of using them in patients. These results show it may be as little as five years before this advance can be used to directly benefit patients for a huge variety of illnesses and injuries. Anne Bishop
advance believe congress convince core perception value voters work
The perception by the core value voters is that Congress has not done enough to advance their core issues. We believe they have been at work, but there is more work to be done to convince their constituencies. Tony Perkins
advance appreciate gotten help support thank
We appreciate all the help we have gotten so far. Without the support of the community, we wouldn't have the school. We want to thank everyone in advance for everything done. Jo Brown
advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline.
advance clinical company eventual experience extensive manage partner pleased rapidly required technology
We are pleased to partner with a company with the extensive cardiovascular experience required to rapidly advance our technology through the clinical development and regulatory process, and manage the eventual manufacturing and commercialization. Robert Harris
advances agreement businesses company enter exit focus growth mature pleased reputation sale strategy
We are pleased to enter into the agreement with Nekoosa Coated Products, a company with a well-earned reputation in the industry. Also, the sale advances Nashua's strategy to exit non-strategic and mature businesses and focus on growth opportunities.
advance conference easy fall girls ncaa rattled season straight stuck tournament wins
We started the season 5-5 and it would have been easy to fall off. The girls stuck with it, and we rattled off 14 straight wins at one point. Getting back to the conference championship and making the NCAA tournament is pretty important to our players. Hopefully, we will advance and do well.
advances believe imminent item law near pricing recent require
We believe that recent and imminent technological advances will require a modernization of the item pricing law in the near future.
advances deaths direct everyday seeing
We are seeing advances everyday and deaths are decreasing. It is a direct correlation.
contracts course others
The others had contracts that were up during the course of the year. Don Howe
contracts production safe ways
We were arrogant, we thought we were safe because we had our production contracts with the big studios. Now we have to look at new ways to grow.
contracts cool couple format graphic novels picturing poems stories until various work
I hadn't thought specifically about doing graphic novels until a couple of my friends got contracts for them. Then I started picturing how various of my stories or poems would work in an illustrated format and thinking how cool that would be. Sharon Shinn
contracts counties several signed step
We have signed contracts with several counties and that's a step that's required.
contracts extremely huge mind offering peace signing
Signing one of those (long-term) contracts is extremely pessimistic. What they're offering is peace of mind at a huge premium.
contracts earnings energy existing favorable forward increases led past prices prospect sharp six wholesale
The prospect of favorable new energy contracts for PPL as existing long-term contracts expire, in conjunction with sharp increases in forward wholesale energy prices over the past six months, led us to increase our long-term earnings forecast.
contracts fleet future gut plan
To gut our contracts when you don't know what the future fleet plan is going to be is irresponsible.
contracts mobile reasons reduce stream
One of the reasons that they feel like they can reduce the exclusive-use contracts . . . is that they've got higher-speed, more mobile and larger-capacity payloads in the contract stream now.
contracts feeling
My feeling is contracts should always be honored, Gary Bettman
downside low possibly
The only downside that I see is possibly a low appraisal.
downside road
The only downside is that they're not as big as SUVs and can't go off road as much.
downside few italian restaurant smell yard
The only downside is that your yard will smell like an Italian restaurant for a few hours. If that's a downside.
downs happens ups
We started out like gangbusters. We were really clicking, but as what happens in every game, there are ups and downs and ebbs and flows. Kerry Collins
downs happens ups
We started out like gangbusters, ... We were really clicking, but as what happens in every game, there are ups and downs and ebbs and flows.
downs family guy life living loves singing talking ups
I'm from a working-class family. We didn't have a lot, but we had the arts. You're talking to a guy who is making a living at doing what he loves doing - acting, singing and dancing. So any career ups and downs were not that significant to me; the only things that really powerfully impinged on me were my losses, and there were many in my life. John Travolta
downs gets personal trouble
We're not disciplined enough to do things correctly, ... We take downs off and it gets us into trouble. It's personal fouls. It's holding. It's facemask. It's the whole gauntlet of stuff.
downs early game helped hit missed score short
She didn't hit greens, but her short game helped her. She had a lot of up and downs to keep the score going. And she missed a lot of putts early on, kind of like I did, but in the end she was pretty solid. Annika Sorenstam
downs ups
She had her ups and downs during those days.
economy currency biosphere
Other things, like capitalism, free enterprise, the economy, currency, the market, are not forces of nature, we invented them. They are not immutable and we can change them. David Suzuki
economy mistaken perception train
The perception that the U.S. economy is a runaway freight train is mistaken -- things are slowing.
economy extent fact issues ongoing pace recovery slowing strength week whether
The ongoing issues are the strength of the economy and whether or not the pace of the recovery is in fact slowing down. One of the important things this week will be to see the extent of the damage. John Davidson
economy growing region resilient seeing seems
We are seeing a very resilient economy and one that seems to be growing in every part of the world. Just about every region is growing and it's very encouraging.
economy fears finds full hard
There are some fears that the post-war U.S. economy still finds it hard to go back into full gear.
economy global wine
We're in a global wine economy now. If you're out of grapes, you're out of grapes.
economy fact fiscal growing monetary stimulus
When you think of all the fiscal and monetary stimulus we've had, we should have the economy growing at 5 or 6 percent. The fact that we're not is the story. David Rosenberg
economy government human science useful
The government will see that human spaceflight is useful - for science and the economy - and inspirational. Helen Sharman
economy few growing industry innovation particular past rapid seen technology within
We have seen China's economy growing at 8-9% over the past few years and in particular within the telecom industry there has been rapid developments in technology and innovation enhancements, Patricia Russo
fastball utilize
We want to see his command, we want him to utilize his pitches, ... We also want to see him use his two-seam fastball and sinkerball. Clint Hurdle
faster players ran team
The other team had a lot more Afro-American players than we did and they ran a lot faster than we did.
fast kept
We started off fast and we kept it up. Ken Hitchcock
fast good
We started fast and did some good things early. O. J. Simpson
fast field happen
When you've got a 20-horse field and a fast pace, anything can happen out there.
fastidious few
There is one thing that matters, to set a chime of words tinkling in the minds of a few fastidious people. Logan Pearsall Smith
faster downsizing ifs
Here's the thing, you just have to drive a lot faster, and if you don't get there, we're both fired. Bill Murray
fast good guys hold job moving players supposed today took
We have to have a different mind-set - that was established today in our meetings, ... I think our players took hold of it and did a good job of practicing. It was a pretty fast practice, guys moving around where they were supposed to go. Herman Edwards
fast hope intention loose means playing side time
We have no intention of playing fast and loose with this document, with the OAU process, ... We only hope that this time around the other side really means what it says. Meles Zenawi
government people should
People shouldn't be afraid of their government. Governments should be afraid of their people. Alan Moore
government giving enemy
In the time of Mrs Thatcher the church, to give it its due, spoke out and was an enemy of the Conservative government. Alan Green
government favors corruption
In general, corruption tends to exist whenever governments have favors to extend, or something to sell. Alan Greenspan
government purpose regulators
The guiding purpose of the government regulator is to prevent rather than to create something.
government support political
Stripped of its academic jargon, the welfare state is nothing more than a mechanism by which governments confiscate the wealth of the productive members of a society to support a wide variety of welfare schemes. A substantial part of the confiscation is effected by taxation. But the welfare statists were quick to recognize that if they wished to retain political power, the amount of taxation had to be limited and they had to resort to programs of massive deficit spending, i.e., they had to borrow money,by issuing government bonds, to finance welfare expenditures on a large scale.
government self credit
We are in the midst of a once-in-a-century credit tsunami. Central banks and governments are being required to take unprecedented measures. Those of us who have looked to the self-interest of lending institutions to protect shareholders' equity are in a state of shocked disbelief.
government giving needs
We need an amendment that gives us the right to vote protected by the federal government and the Constitution. Al Sharpton
government america united-states
If we have any problems, it's always with the government of the United States. Akbar Hashemi Rafsanjani
government opportunity work
We want the opportunity to work with the government on this.
grows ifs
It is good to act as if. It is even better to grow to the point where it is no longer an act. Charles Caleb Colton
growing-up women thinking
... the woman who grows up with the idea that she is simply to be an amiable animal, to be caressed and coaxed, is invariably a bitterly disappointed woman. A game of chess will cure such a conceit forever. The woman that knows the most, thinks the most, feels the most, is the most. Intellectual affection is the only lasting love. Love that has a game of chess in it can checkmate any man and solve the problem of life. Charles Dickens
growth credit might
There might be some credit in being jolly.
growing-up people needs
Many people never grow up. They stay all their lives with a passionate need for external authority and guidance, pretending not to trust their own judgment. Alan Watts
growing-up book comic
I didn't really grow up a comic book fanatic. Alan Ritchson
growing late critique
A lot of the critique of our growing mechanization was actually at its strongest, and arguably at its most perceptive, during the late '60s.
growing bigs distrust
There's been a growing dissatisfaction and distrust with the conventional publishing industry, in that you tend to have a lot of formerly reputable imprints now owned by big conglomerates.
growing-up school boys
Growing up in the Boroughs, I thought I must be the cleverest boy in the world, an illusion that I was able to maintain until I got to the grammar school.
growing-up hands world
A world grows up around me. Am I shaping it, or do its predetermined contours guide my hand?
lessons shapes pay
Everything shapes you to be the person you are today. Sometimes hard lessons pay off dividends. Al Jourgensen
lessons matter facts
No matter what you do, you can never please everyone. And that was the hardest lesson to learn. In fact, I'm still learning it. Chris Colfer
lessons painful evolve
Unless you continually work, evolve, and innovate, you'll learn a quick and painful lesson from someone who has. Cael Sanderson
less looking toward
We are looking less favorably toward 2016 bidding at this moment, Peter Ueberroth
less mean point push start sure year
We are at the point of the year where if you push him back, it could mean one less start at the end of the year. We need to make sure that he can pitch. If we do push him back, we want to make sure we have the matchups we need at the end of the season. Mike Scioscia
lessons used teach
I used to teach dance lessons. Eartha Kitt
lessons rewards hell
The lesson is, the rewards in life don't always go to the biggest, or the bravest, or the smartest. The rewards go to the dogged; and when your going though hell, to the person who just keeps going. Bear Grylls
lessons-to-be-learned alive process
Success is a process that continues, not a status that you reach. If you are alive, there are lessons to be learned. Denis Waitley
lessons firsts given
To know ourselves, is agreed by all to be the most useful Learning; the first Lessons, therefore, given us ought to be on that Subject. Eliza Haywood
mildness endure magnanimity
Magnanimity consists in enduring tactlessness with mildness. Democritus
mild speech
She's very mild in her speech, but she's hard-working.
mild obviously
Ed Miliband is obviously a mild guy. I don't expect him to pretend to be a pugilist. Robert Webb
mild seals weather
Because of the mild weather we've been having there's no ice, and the seals now have to find an alternative place to pup.
mild surprise
I think you can characterize it as a mild surprise that we are here.
mild storage winter
We've had a mild winter and we've got a higher-than-normal storage inventory.
mild raining relatively spring
I think it will keep raining well into March. I also think spring is going to be relatively mild and dry.
mild though
I don't want to act as though my deployment was particularly rough, because it wasn't. I had a very mild deployment; I was a staff officer. Phil Klay
mild predicted storm took
After the groundhog, they predicted a more mild winter. The storm took me by surprise.
pain real power
To know the pains of power, we must go to those who have it; to know its pleasures, we must go to those who are seeking it: the pains of power are real, its pleasures imaginary.
pain age youth
The seeds of repentance are sown in youth by pleasure, but the harvest is reaped in age by pain.
pain shadow substance
Pain may be said to follow pleasure as its shadow; but the misfortune is that in this particular case, the substance belongs to the shadow, the emptiness to its cause.
pain shadow may
Pain may be said to follow pleasure as its shadow.
pain angel reflection
If there be a pleasure on earth which angels cannot enjoy, and which they might almost envy man the possession of, it is the power of relieving distress--if there be a pain which devils might pity man for enduring, it is the death-bed reflection that we have possessed the power of doing good, but that we have abused and perverted it to purposes of ill.
pain memories vices
Drunkenness is the vice of a good constitution or of a bad memory of a constitution so treacherously good that it never bends till it breaks; or of a memory that recollects the pleasures of getting intoxicated, but forgets the pains of getting sober.
pain doors hands
Sensibility would be a good portress if she had but one hand; with her right she opens the door to pleasure, but with her left to pain.
pain hands years
On the eve of long voyages or an absence of many years, friends who are tenderly attached will seperate with the usual look, the usual pressure of the hand, planning one final interview for the morrow, while each well knows that it is but a poor feint to save the pain of uttering that one word, and the meeting will never be. Should possibilities be worse to bear than certainties?
pain god-love accepting
Regardless of the source of our pain, we must accept that God knows, God loves, and God is at work. Charles Stanley
raising totally vegan
Vegetarian is like raising a kid Mennonite. It's difficult but not that different. Raising your kid vegan is like being Amish. A totally different world. Victoria Moran
raising readers require
Questions that require answers are what keep readers going - and the place to start raising those questions is with your very first sentence. Nancy Kress
raising rest
We're doing very well. But we can do better. We'll have to (do) better, because they keep raising the standards. This is one of those things where you can't rest on your laurels.
raising rest
We're doing very well. But we can do better. We'll have to better, because they keep raising the standards. This is one of those things where you can't rest on your laurels.
raising
I think Harman should be commended for raising so much in the district.
raising teach three women
Raising three girls, I think it's important to teach them to support other women. Martina McBride
raising
This is big and this is important. This is not about raising money, it's about raising interest.
raising
It's about being with friends and raising money, ... To me, that's most important. Tracy Austin
raising woman
It will be 'Roseanne'-ish in nature, a real woman raising two kids. There won't be any winking at the camera, no double-entendre jokes.
spares
... do not spare me in anything -- let there be less and less of me in everything. Mother Teresa
spares
On ne re c° oit pas la sagesse, il faut la de couvrir soi-me" me, apre' s un trajet que personne ne peut faire pour nous, ne peut nous e pargner. We do not receive wisdom.We must discover it ourselves after experiences which no one else can have for us and from which no one else can spare us. Marcel Proust
upset atmosphere generations
We are upsetting the atmosphere upon which all life depends. In the late 80s when I began to take climate change seriously, we referred to global warming as a "slowmotion catastrophe" one we expected to kick in perhaps generations later. Instead, the signs of change have accelerated alarmingly.
upset lines bottom
Bottom line is, if someone says something about me and it upsets me, it's true. Byron Katie
ups-and-downs stills
There's ups and downs in this love. Got a lot to learn in this love. Through the good and the bad, still got love. Beyonce Knowles
upset way expecting-something
Only way you can you get upset is when you expecting something. Bernie Mac
upset tea cups
Inkstands and tea-cups are never as full as when one upsets them ... Edith Wharton
upset looks next
You look sad even though we just met No need to get upset But I got a show, gotta go, so I thank you And if you wanna still get sexed down You could catch the next Greyhound But until then, I gotta go, so I thank you Eamon
upset dairy-products punjabis
Nothing soothes an upset Punjabi like dairy products. Chetan Bhagat
upset attention four
The Four Rules of Life: 1. Show Up 2. Pay Attention 3.Tell the Truth 4. Don't be upset at the results. Bill Vaughan
upsets watching
Watching upsets and being a part of an upset are two different things. Anthony Brown