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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
aiming believe students
We want to see more students aiming for four-year colleges. I believe that with AVID, that will happen. Arthur Greenway
aiming cup league return win
We are aiming to win the league and cup this season, and also return to Europe. Colin Clarke
aiming champions high league team
We are aiming high in the Champions League and you will see a different team on Tuesday, Oliver Kahn
aiming rooms trading
We are aiming for trading rooms in Europe. Andreas Barth
aiming people
We are aiming for around 425 people to come. Jarret Izzo
aiming best delighted finish football good match played shown six top
We started out aiming at the top six so we have done well. We have played some good football and shown we can match the best so I am delighted with the lads. We want to finish on a high. Michael Watson
aiming except recorded recording
Nothing could be recorded in those days except by aiming a movie camera at the television screen. It was at least another 10 years before they had any kind of recording medium. Nigel Kneale
aiming board breakup company concerns current higher limited problem pursue returns risky serious strategy ultimately whether yield
We have no problem with the board aiming for a higher price. However, should the company pursue the limited breakup alone, we have serious concerns about whether that risky strategy will ultimately yield better returns for current shareholders. Mitchell Corwin
aiming hike leave march open question whether
What they're going to be aiming for is to leave open the question of whether they hike on March 28. Jan Hatzius
bring community otherwise services
We want to try to bring services to our community that would not otherwise be here. Jedd Gould
bring company concept ramp roll somebody time
We want to take the concept as big as we can. To really ramp the company up and roll it out the way we want to, we really wanted to take some time and bring somebody in of this caliber. Don Reynolds
bring candidates good neither people
The other two candidates are good people but neither one of them would bring real reform. John Shadegg
brings element entire grant hill locker looks positive room strong sustain team time
The other thing you get with Grant Hill is the leadership, the professionalism and the good, strong positive character. He brings that element into the locker room and into your team as well. He's just doing really well and it looks to me that this time he'll be able to sustain it the entire season. Johnny Davis
bring defense drive helping kick offense passing played score teams using weapons
The other teams I played on were more keyed in on defense. The defense was going to bring our offense and that was it. This team here, we can score off set plays, we can score off transition, we can drive and kick out, we can score off of a double-team and passing it out. We have a lot of weapons to play with. We're just using them out there and it's helping us score points. Carl Krauser
brings family food power together
The Power of Food is really Spiritual. It not only brings the whole family together on the same table, but also brings the whole world together. Vikas Khanna
bring justice needs pay son
The person who did this to these two needs to pay for it. He will never bring my son back or Sebastian back, but I want justice done. J. M. Roberts
brings good pc personal together tool web
The personal Web is a tool that brings together all the good things we're used to in a new world of communications, ... It will make us think differently about the PC and the Internet. Bill Gates
bring guys reason worse
The only reason I think about it is that you guys (reporters) bring it up. It's worse if you think about it, so I try not to. Chris Hernandez
create family force great period rehearsal shoot time wonderful
What was really wonderful about the 'Doubtfire' shoot is that we had this really long rehearsal period in the beginning. That was a great time to get to know each other. We got to know each other and to create the family vibe. So we really didn't have to force it. Lisa Jakub
created creates federal government job people project work
The federal government has never created one job that is sustainable long term. It creates government project work but not creating real work where people are. Michael Steele
created general government inspector position
The position of the (Interior Ministry) general inspector was not created by the government, it had been there before the new government was formed. Ghazi Hamad
create people protect
the people who create it want the most to protect it. John Brown
create elementary industrial school tucked
We've actually tucked the elementary school back with the industrial to create a little more buffer. Aaron Guillen
created defense floor greatest man played press switch
We started out on a full-court press, but we had to switch to a man all over the floor when the press was not working. We created a lot of turnovers and our defense made opportunities for our offense. That is the greatest defense we have played all year. Jerome Antone
creates offense running spread
We spread the offense to spread the opposing defenses and that really creates running room. Eric Keller
create wherever
Wherever he goes, he's probably going to create a lot of controversy. That's why he's one of the greatest. Omar Vizquel
create davis expect point raiders walk
When you walk out there, when you into that stadium, you walk out there with a presence. Mr. Davis called it a swagger. I just want to get back to the point where when we walk into a stadium, they know the Raiders are in town. And when we walk into the Coliseum, the Raiders are here. ... We've got to create that attitude, and that's what I expect to do. Art Shell
critical focus stretch winning
We want to see if we can get that done, ... So our focus is winning the first one. This is a very critical two-week stretch for us. Tony Dungy
critical stage
We are at a very critical stage in our negotiations, John Broughton
critical people time
We're in that critical time that people can be rescued, ... If we don't get out thereto and do it now, then they're going to die. Pat Sullivan
critical-spirit habit critical
Make it your habit not to be critical about small things. Edward Everett Hale
critical literally room
We have no room literally to spare. Every game, every day is critical to us. Dave Wannstedt
critical injuries minor multiple serious
We have multiple critical injuries and multiple serious injuries and some minor injuries, Willie Williams
critical department fatal suffers whenever
Whenever the department suffers a fatal fire, we take a constructive, critical look at the event. Thomas Galvin
critical our-lives anything-is-possible
Health is the most critical thing in our life. With your health anything is possible, without it you can't do anything. Bill Walton
critical people reporters time truth war whining
While many people think that we as reporters are whining and that this is a time of war, we are really the conveyors of truth in a very critical time and people need to know that truth. Judd Rose
energy film glances
On film you put all your energies into a single glance. Alan Rickman
energy capacity plans
My plans have always exceeded my capacities and energies C. Wright Mills
energy favorite leadership looking market odds sector sleeping
We are looking for the energy sector to be the odds on favorite for market leadership that could reawaken the sleeping IPO giant. David Menlow
energy extending game happy lead locker room stressed
We stressed in the locker room before the game that we wanted to come out with energy and intensity, and we didn't do that right at the start. But I was happy with us extending our lead and making that run. Tyler Brand
energy lack maybe quick rest spots watch
When you watch film, you see we're maybe not getting to spots quick enough. Or there are some things where we lack the energy that I know when we get rest that we have. So we'll see. Flip Saunders
energy gives might novel people resolve running sentence series wants
A series of small but real accomplishments gives people the energy and confidence to continue. For instance, a person who wants to write a novel might resolve to write one sentence each day. Or a person who wants to start running might resolve to run for one minute. Gretchen Rubin
energy done county
If I had the energy, I would have done it all over the county. Edward Hopper
energy plant feels
For my own health, I thought it was better to eat a plant based diet. I'm going to be 60 soon and I have boundless energy and I feel really good, so I'm all for it. Ed Begley, Jr.
energy feminine grew
I grew up around a lot of feminine energy. David Walton
exactly nashville reason
We want them to see exactly the way we do it in Nashville ? there's no reason to change. Walter Miller
exactly stay
We want to stay exactly as long as they need and not one day more. Dr. Currier
exactly-is data ducks
What, exactly, is the internet? Basically it is a global network exchanging digitized data in such a way that any computer, anywhere, that is equipped with a device called a 'modem', can make a noise like a duck choking on a kazoo Dave Barry
exactly pieces sure
The other pieces I'm not exactly sure of. Bob Poole
exactly four positives talking
The positives are we got four underclassmen out here to see exactly what we were talking about. Carter Jordan
exactly time
I read a lot, all the time, but often I read books for research, or because they're interesting to me in some way, even if they aren't exactly 'pleasurable.' Gretchen Rubin
exactly heard
We have to find out what is exactly happening. We have all heard about this then we have to see if it is confirmed. Friso Abbing
exactly geologists moving
We have to find out exactly what's going on with the slide. Geologists say it's still moving slowly. John Cunliffe
exactly
We have to find out exactly what is happening. Friso Abbing
experience
It is far better to borrow experience than to buy it. Charles Caleb Colton
experience taste helpful
One has to taste an experience for oneself and find out if the thing is genuine or helpful. Then, before discarding something, one has to go further, so that one gets firsthand experience. Chogyam Trungpa
experience incredible powerful pushed scores stories wonderful work
It was a wonderful experience to work with Sylvia. She pushed me to be more powerful with my acting, and she told me scores of the most incredible stories I've ever heard. She is amazing. Lukas Haas
experience hope negative remind talk whenever
I hope that whenever my daughter has a negative experience, I'm there to talk about it and remind her how we feel when it's done to her so that she doesn't do it to others. Lorraine Toussaint
experience lived richest
The person who has lived the most is not the one who has lived the longest, but the one with the richest experiences Jean-Jacques Rousseau
experience
We've all had experience to this point, which has been good. Mike Cisco
experience loved side totally west
West Side Story. It's a totally new experience for me. I've always loved theater. Diana DeGarmo
experience fools start wise
We start as fools and become wise through experience African Proverb
experience mental playing talent top tremendous
When you've got talent from top to bottom, everybody's playing to count. It's a tremendous experience to play without that mental cushion. Dan Brooks
experts
I'm not a marriage expert, quite clearly. Cathy Freeman
experts professors respect
We respect not only professors and experts but also technologists who have their own inventions, Wen Jiabao
experts form good improve moves
When we are on the set, there are always experts there to choreograph the moves and improve your form so you look good for the camera. Thuy Trang
experts agree forecasts
When all the experts and forecasts agree, something else is going to happen Bob Farrell
experts field help looking whenever
Whenever you're looking at something like this, it's important to get as many experts in the field to help you. Carol Sanders
experts looks may
I look at myself more as a storyteller than a screenwriter, as pretentious as that may sound, but that's what really attracts me to TED Talks. For me, the really effective ones are being presented by expert storytellers. Damon Lindelof
experts finance personal-finance
I don't really consider myself to be a personal finance expert compared with some others. There are quite a few that know a lot more than I do. Ben Stein
experts want
I'm not an expert, but I want to be. Ben Nicholson
experts heard higher job numbers package stimulus today
We heard much higher numbers today of the stimulus package from our two experts than I anticipated we would hear. In other words, if you're going to do something, it better be something significant enough to get the job done. Charles Grassley
helping-someone achievement saving
Helping someone come to a saving knowledge of Christ is the greatest achievement possible. Charles Stanley
helping conservation protect
The more you know about a species, the more you understand about how better to help protect them. Alan Clark
help understand
We want them to understand we're here to help and do everything we can, Mike Harris
help organize
We want to see how we can help organize the transfer. Javier Solana
helping-others names way
Helping others is a question of being genuine and projecting that genuineness to others. This way of being doesn't have to have a title or a name particularly. It is just being ultimately decent. Chogyam Trungpa
helping conspiracy crime
Prosecutors tend to love conspiracy charges because the rules of evidence are easier, meaning you can get more in to help prove a crime. David Shuster
helping-someone stories sometimes
I love helping someone else tell their story, but I like being the storyteller sometimes. David Schwimmer
helping ability
All of those measures of relationships that you have in your life help feed your and inform your ability to act. David Koechner
helping help-me help-yourself
Seriously? You won’t help me?” “Help yourself get killed? No, I won’t. Dave Barry
interested start sure talking
We want to start talking (soon) and make sure we let them know we want them. They've let us know they're very interested in talking. Dennis Morgigno
interested
We are at capacity. We are interested in getting new equipment. John Parsons
interested quick safe using
We're interested in using it if the waivers are in place and it's a safe alternative, ... This is not a quick fix. It could be a multi-year process. Valerie Miller
interested spend time uses
We're interested in knowing, ... how much each one of you uses the Internet. How much time do you spend on it? Judy Woodruff
interested parties solution
We?re in discussions with other interested parties ... to see what kind of solution we could come up with. Valerie Cunningham
interested plays son
We have a son that plays for one of the schools. I'm very interested in men's basketball. Charles Clarke
interested whether
whether or not I'd be interested is a whole other issue. Rod Paige
interested movies
When I was making my first films, I was very interested in Hollywood B movies. Park Chan-wook
interested
We're so interested in it because it's different for everyone. Joyce Brothers
mass-extinction exception-to-the-rule survival
Extinction is the rule. Survival is the exception. Carl Sagan
mass-destruction wmd goal
We should be hell bent on getting those weapons of mass destruction, hell bent on having a credible approach to them, but we should try to do it in a way which keeps the world together and that achieves our goal which is removing the... defanging Saddam.. Carl Levin
massive preparing relief
We are preparing for a massive relief operation, Ruud Lubbers
mass
You can't create a mass market if you don't have a common standard. Henry Samueli
mass-destruction iraq long
The liberation of Iraq was part of a broader effort to seriously confront the greatest threat to world security: rogue states capable of obtaining long range weapons of mass destruction. Armstrong Williams
mass-destruction weapons destruction
Those weapons of mass destruction have got to be somewhere... Nope, no weapons over there... Maybe under here. George W. Bush
mass-destruction weapons destruction
Fear is a weapon of mass destruction. Dennis Kucinich
mass-destruction tyrants iraq
There is no doubt that Saddam Hussein's regime is a serious danger, that he is a tyrant, and that his pursuit of lethal weapons of mass destruction cannot be tolerated. He must be disarmed. Edward Kennedy
mass-destruction years iraq
We have known for many years that Saddam Hussein is seeking and developing weapons of mass destruction. Edward Kennedy
national-security gross negligence
Gross negligence in handling national security is a felony. Bill O'Reilly
national number people playing team whenever
Whenever you can be a part of something where the number one team and number two team are playing each other on national television, it is special. How many people get that opportunity? Lee Melchionni
national operating response
We were already operating under the National Response Plan. Russ Knocke
national sang
I sang at the Inaugural prayer service at the National Cathedral. Michael W. Smith
national persuaded reform trying unwilling
We've become persuaded that, after two years of trying to reform the national AFL-CIO, it is unwilling to change, John Wilhelm
national spell
We're back-to-back national champions. You can't spell BCS without USC. LenDale White
national spell
We're back-to-back national champions, ... I know you can't spell BCS without USC. LenDale White
national people power russian traditions
Russian democracy is the power of the Russian people with their own traditions of national self-government, and not the realisation of standards foisted on us from outside. Vladimir Putin
national people realise
What governments and people don't realise is that sometimes the collective interest - the international interest - is also the national interest. Kofi Annan
people may medical
It is astonishing how much more anxious people are to lengthen life than to improve it; and as misers often lose large sums of money in attempting to make more, so do hypochondriacs squander large sums of time in search of nostrums by which they vainly hope they may get more time to squander. Charles Caleb Colton
people solitude multitudes
A multitude of people and yet solitude. Charles Dickens
people governing whole
My faith in the people governing is, on the whole, infinitesimal; my faith in the people governed is, on the whole, illimitable. Charles Dickens
people words-of-wisdom selfishness
Others had been a little wild, which was not to be wondered at, and not very blamable; but, he had made a lamentation and uproar which it was dangerous for the people to hear, as there is always contagion in weakness and selfishness. Charles Dickens
people words-of-wisdom want
Mrs. Boffin and me, ma'am, are plain people, and we don't want to pretend to anything, nor yet to go round and round at anything because there's always a straight way to everything. Charles Dickens
people next cleanliness
Cleanliness is next to Godliness, and some people do the same by their religion. Charles Dickens
people scary alive
I have heard it said that as we keep our birthdays when we are alive, so the ghosts of dead people, who are not easy in their graves, keep the day they died upon. Charles Dickens
people enemy
Some people are nobody's enemies but their own Charles Dickens
people romance wonder-woman
Superman/Wonder Woman, people expected, I guess, a lot of romance, or maybe something that wasnt emotionally deep. Who knows? Charles Soule
research copying stealing
Copying one person is stealing. Copying ten is research. Chet Atkins
research just-being producers
But I'm a historian. I wasn't interested in just being a producer, I was interested in doing research and presenting that research to a general public Bernice Johnson Reagon
research fields modern
Never before in the history of the modern research university have entire departments and fields been devoted to purely ideological pursuits. David Horowitz
research sociopath psychopath
I'm a high-functioning sociopath, do your research. Benedict Cumberbatch
research
I don't research anything. Derek Bailey
research can-do
Do not do anything that anyone else can do readily. Edwin Land
research conducting finished
One must stop conducting research before one has finished. Otherwise, one will never stop and never finish. Barbara Tuchman
research sociopath psychopath
I'm not a psychopath, I'm a fully functioning sociopath. Do your research. Arthur Conan Doyle
research world body
I shall not cease learning while I live, nor when I arrive in the spirit-world… and when I again receive my body, I shall …still continue my researches Brigham Young
wind literature wave
Commerce flourishes by circumstances, precarious, transitory, contingent, almost as the winds and waves that bring it to our shores. Charles Caleb Colton
wind fire tale-of-two-cities
Then tell Wind and Fire where to stop," returned madame; "but don't tell me. Charles Dickens
wind rising sawdust
It had grown darker as they talked, and the wind was sawing and the sawdust was whirling outside paler windows. The underlying churchyard was already settling into deep dim shade, and the shade was creeping up to the housetops among which they sat. "As if," said Eugene, "as if the churchyard ghosts were rising." Charles Dickens
wind east now-and-then
The wind's in the east. . . . I am always conscious of an uncomfortable sensation now and then when the wind is blowing in the east. Charles Dickens
wind arctic knows
I don't know where this Arctic wind has come from but it's freezing! Alan Green
wind outsiders balloons
I've just always been a fan of really fringy, outsider things, and I've always been a balloon in the wind, in terms of where that takes me. Chris Bauer
wind hair passionate
I want to live a passionate life. I always want to feel the wind in my hair. Dave Gorman
window tapping
Someone was tapping on the window. Dave Barry
wind sea voice
There is nothing as relaxing as being out on the open sea, listening to the waves and the wind and the sails and voices downstairs yelling "HOW DO YOU FLUSH THESE TOILETS?" Dave Barry