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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
call clear information resources
We want them to have clear information about this subject, and resources to call on. Fred Engh
call effort takes
We want them to call us. It takes a collaborative effort with our partners. Steve McDonald
calling answers levels
The honest answer is more complex. On some level I was sent. Or inspired. Or called. But my calling, such as it was, wasn't a single booming invitation from above (really, is it ever?)... Chris Bohjalian
calling uncomfortable okay
I felt uncomfortable calling myself a writer until I started with 'The New Yorker,' and then I was like, 'Okay, now you can call yourself that. David Sedaris
call number
'Crush' was my first number one on the call sheet. Lucas Till
calling course developed files members prior release sealed
There have been a couple of instances prior to now where members of the House have filed resolutions calling for release of the sealed files which were developed during the course of our committee's investigation. Louis Stokes
call domestic interested whatever
I think I'm interested in these kinds of character dramas, psychological dramas, domestic dramas, whatever you want to call them - comedy dramas. Lisa Cholodenko
calling came consider education later life theater
Film is something that came later into my life. I had a Jesuit education, and I consider acting and the theater as kind of a calling - a vocation. Michael Moriarty
calling reason categories
I see no reason for calling my work poetry except that there is no other category in which to put it. Marianne Moore
culture illusion illusion-of-time
We are living in a culture entirely hypnotized by the illusion of time Alan Watts
culture cult
All culture must have arisen from cult. Alan Moore
culture victimhood not-interested
There is a fetishization of victimization in our culture. And I just am not interested in victimhood. Alan Ball
culture worship christ
Worship is no longer worship when it reflects the culture around us more than the Christ within us. Aiden Wilson Tozer
culture initiative meetings
OneBeat is one of the greatest initiatives in advancing the meeting of cultures worldwide. Dave Douglas
culture biology conditions
Culture is how biology responds and makes its living conditions better. C. J. Cherryh
culture glimpse heritage hosts india next rich
The performances will give a glimpse of the rich culture and heritage of India as the next hosts of the Games. Suresh Kalmadi
culture delay delivering fund ministry promise
We are at our wit's end and most embarrassed by this extraordinary delay on the part of the Culture Ministry in delivering on a promise to fund the event. Patrick Arnold
culture host issues
There are big culture issues in these films, contemporaneous issues, and he's about as issue-oriented as a host can be. Gil Cates
earlier heads hit looking proved toward
We're in a funk, definitely. I don't even know what to say. We can hit the ball. We proved that earlier in the season. But we're still confident. We've got our heads up and we're looking toward tomorrow. Matt Bowman
earlier gone gotten hit maybe warm
When he first hit it, I thought it was probably gone. It had just gotten cold. Maybe earlier when it was warm it would have gone out. Jermaine Dye
earlier feet felt pick year
We felt like we could pick up 94 feet - something we were doing earlier in the year when we had more bodies. Doc Sadler
earlier force issue
We're going to have to force the issue a little earlier than we wanted to. Steve Sherman
earlier employ gifts less pastor presidency
The earlier practice of the Church had been more or less to employ in worship under the presidency of the pastor or pastors, the gifts of the congregation. Robert Rainy
earlier girls hope maria open today
Like everyone else, they wanted to take Hope and Maria out of the game. I told the girls earlier today that someone is going to get open shots. Bret Tuetken
earlier kids michael
A lot of my friends were a lot into theatre a lot earlier than I was. A lot of my friends were kids who were in The Broadway Kids and the kids auditioning for Gavroche in 'Les Miz.' I was never that kid. I was weaned on Michael Jackson. Not literally, because that would have been odd. Erich Bergen
earlier might recession recovery vigorous
We might be out of recession already. The recovery could be more vigorous than earlier anticipated. Ken Goldstein
earlier good last supported year
She had a good year last year. If we could have supported her at all with some runs, especially earlier in the year, she would have had a much better record. Mike Harper
environment progressive grew
I will say that the environment I grew up in was not the most progressive. Alan Ball
environmental dollars protection
Over and over, we hear politicians say they can't spend our tax dollars on environmental protection when the economy is so fragile. David Suzuki
environment
We all live downstream David Suzuki
environmental body embedded
Each of us now has 2.27 kg (5 lbs) of plastic embedded in our bodies. David Suzuki
environmental cost lines
The fact of the matter is that today, stuff-selling mega-corporations have a huge influence on our daily lives. And because of the competitive nature of our global economy, these corporations are generally only concerned with one thing - the bottom line. That is, maximising profit, regardless of the social or environmental costs. David Suzuki
environmental waste recycled
In nature there is no such thing as waste. In nature nothing is wasted; everything is recycled. David Suzuki
environmental garbage worn
There is no place where we can safely store worn-out reactors or their garbage. No place! David R. Brower
environmental wrecks energy
It seems that every time mankind is given a lot of energy, we go out and wreck something with it. David R. Brower
environment finite growth unlimited
Unlimited growth in a finite environment is impossible. Hanno Langenhoven
fairly national performance season soccer team
The performance of the national team is very important. This season soccer has been fairly abysmal. Jon Holmes
fairly five takes
When I am working on an epic-length book, the writing process is fairly long. It takes from four to five years to get through all the drafts. The book is done when I am exhausted. Gunter Grass
fairly few figured good guys henry last lost matches realize tournament wrestle
We wrestled fairly well today. We wrestled at the Bo Henry Tournament last week; we wrestled really well there. Today, we didn't wrestle as good as we could've and I think the guys realize that; I think they kind of figured out that there may have been a few matches we lost that we should've won. Zach Errett
fairly fruit minimal since
We're hoping, of course, it's going to be fairly minimal since a lot of that fruit had already been picked. Casey Pace
fairly hope hopefully knew played playoffs results week
We knew this was going to happen, ... We knew probably a week before the playoffs we'd get it done. We did it. Everything has been right on time. I just hope we get the same results as the other shots. I think I played fairly well after the shots, so hopefully that will continue. Larry Walker
fairly healthy
When they were young teenagers, most of the participants had fairly healthy behaviors. Christine Bachrach
fairly feels hardly injured weeks
Yeah, two or three weeks ago I was fairly snappy. I've never been injured before and this year it feels like I've hardly played. Lee Westwood
fairly people time
People tell me all the time that I look forbidding or aloof. That doesn't bother me much - I am fairly private, withdrawn, and... distant, I guess. But, um, I think that's okay. Ric Ocasek
fairly heart hopes major soul
When you put your heart and soul into something for 10, 15 years, it's a career. You do it in the hopes you can be fairly evaluated and make it to the major leagues. Andy Roberts
forming government proceed
We want the negotiations on forming a new government to proceed quickly. Matthias Platzeck
formal terrible settings
I'd make a terrible practitioner of any religion in any formal setting. David Knopfler
form novel mediums
The novel has always been the form that incorporates other forms. For me, it has always been the ultimate medium. Chad Harbach
form disguise behinds
Lifelessness is only a disguise behind which hide unknown forms of life. Bruno Schulz
form good including lump magical neutrality tolerate toward
We can no more tolerate neutrality and benevolence toward every conceivable form of discourse, including that of magical thinking, than we can lump together executioner and victim, good and evil. Michel Onfray
form protesting
We are protesting a new form of dictatorship and authoritarianism. Abhisit Vejjajiva
form forward great looking moment
We're in great form at the moment and looking forward to every match. Alex Ferguson
form rapper whatever whereas
I'm an entertainer, so in whatever form I entertain... The thing about being a rapper is that you have more control over your form, whereas with acting you have to compromise a lot. Method Man
formed studios
I think the big studios shaped and formed the artists that they put under contract. Nicolas Roeg
lived seemed
If genetic research doesn't seemed to have lived up to its therapeutic promise, it's because sequencing is just too slow and expensive. Luke Nosek
lived love modeling
When I was a little girl, I lived for modeling and fashion - I used to love, love, love modeling. Chanel Iman
lived passed people spend spent time traveled
I was very fortunate, because I don't think many people get to spend time with their great-grandfathers. So, he passed away when I was 15, so I spent a lot of time with him. We lived together. He traveled a lot, but when he was here, we lived together. Kumar Mangalam Birla
lived tribal weeks
I lived in grass huts in a jungle in the Philippines for three weeks with tribal people. Evangeline Lilly
lived parent pleasure short
Short lived pleasure is the parent of pain. Proverb Proverb
lived seem society type
She doesn't seem to have been the society type or one to flaunt her wealth, but she lived well. Wendy Miller
lived massacre native settlers struggles whitman
We use the Whitman Massacre as a representation for a lot of the struggles between the incoming settlers and the Native Americans who lived here. Robert Owens
lived love played
I love the way the game of golf is lived and played in Scotland. I always have. Tom Watson
lived
My parents were ordinary people; we lived in a small apartment. Viktor Vekselberg
looked man pieces
There are biographies, I looked at a lot of photographs of him, I heard his voice over and over and over again. You get in there and get to know the man by all of those pieces of information. David Strathairn
looked plays stopped worthy
We stopped for some plays that weren't worthy of being looked at. David Parry
looked
When I looked at the other artists when I first started at Marvel, I was surrounded by giants. It was very intimidating. Herb Trimpe
looked people
When I was a kid, I always looked up to people like B.B. King and Ray Charles. Daryl Hall
looked lots saw stands wrestle
When I was a freshman, I didn't wrestle as well here as I thought I could. I looked up at the stands and saw lots of people. Troy Dolan
looked rearview united
United just looked in the rearview mirror, and they do not want to go back from where they came. Terry Trippler
looked
Yes, I am physical but never go looking for fights. I have been in my share of them but never looked for them. Dave Bautista
looked looking seeing weird
Man, I looked up at the clock, was that right? That was kind of weird too, looking up there and seeing they only had 30. Derrick Byars
looked paradigm realized shifted telescope universe
When I looked through that first telescope my paradigm shifted up course. I realized it was a really big universe and I wanted to know all about it. Carrie Zaitz
modern poet should
How many modern transsexuals are unacknowledged shamans? Perhaps it is to poets they should go for counsel, rather than surgeons. Camille Paglia
modern apprentice
The modern technologist is less 'sorcerer' and more 'sorcerer's apprentice'. Barry Commoner
modern
I would like to do something modern and possibly funny. Dan Stevens
modern solutions
It is a Modern day, and these times need Modern solutions to Modern problems. Corin Nemec
modern-life plumber ifs
If I had it [life] to do all over again, I'd have been a plumber. Albert Einstein
modern outside presidency turned
When a presidency has been turned around, particularly the modern presidency, there's often an outside element. Fred Greenstein
modern presented words
There are no four-letter words or vulgarity. It's got modern themes, but they are presented in an old-fashioned way. Sally Deering
modern people
I don't think people want chains. People want modern conveniences, but they don't want chains. Dean Miller
modern success tolkien
The success that the Tolkien books had redefined modern fantasy. George R. R. Martin
people may medical
It is astonishing how much more anxious people are to lengthen life than to improve it; and as misers often lose large sums of money in attempting to make more, so do hypochondriacs squander large sums of time in search of nostrums by which they vainly hope they may get more time to squander. Charles Caleb Colton
people solitude multitudes
A multitude of people and yet solitude. Charles Dickens
people governing whole
My faith in the people governing is, on the whole, infinitesimal; my faith in the people governed is, on the whole, illimitable. Charles Dickens
people words-of-wisdom selfishness
Others had been a little wild, which was not to be wondered at, and not very blamable; but, he had made a lamentation and uproar which it was dangerous for the people to hear, as there is always contagion in weakness and selfishness. Charles Dickens
people words-of-wisdom want
Mrs. Boffin and me, ma'am, are plain people, and we don't want to pretend to anything, nor yet to go round and round at anything because there's always a straight way to everything. Charles Dickens
people next cleanliness
Cleanliness is next to Godliness, and some people do the same by their religion. Charles Dickens
people scary alive
I have heard it said that as we keep our birthdays when we are alive, so the ghosts of dead people, who are not easy in their graves, keep the day they died upon. Charles Dickens
people enemy
Some people are nobody's enemies but their own Charles Dickens
people romance wonder-woman
Superman/Wonder Woman, people expected, I guess, a lot of romance, or maybe something that wasnt emotionally deep. Who knows? Charles Soule
relatives salt
She (later) went on to Salt because one of her relatives Adnan Badran
relatives
She's by herself, she has no relatives in Manatee. Dave Bristow
relatives waiting
My destination is at a place where my late-friends and relatives are waiting for me to arrive. Shahazad
relatives
I got up at 2 a.m. for this trip. I want to see my relatives and I want to see China, Chen Shui-bian
relatives teach willing
When I was 19 I started pestering my relatives who were willing to teach me. Hankus Netsky
relatives-and-friends giving want
Nothing is more false and more indiscreet than always to want to choose what mortifies us in everything. By this rule a person would soon ruin his health, his business, his reputation, his relations with his relatives and friends, in fact every good work which Providence gives him. Francois Fenelon
relatives starting
He was starting to get inquiries from relatives as to, 'Where's Dad?' John Schultz
relatives-and-friends impossible deceiving
It is not hard to deceive ministers, relatives and friends. But it is impossible to deceive Christ. J. C. Ryle
relatives
The relatives don't know they come here every week, Salvation Army
representation
Anything can be painted without representation. Agnes Martin
representation
Gish was the best representation of where we were at the time. Billy Corgan
represent traditions
I'm a Democrat because I represent the true traditions of the Democratic Party. Kesha Rogers
represent
She had to represent her constituents.... I think all these commissioners do the same thing. Rep. Taylor
represents risky seem
When things seem very risky it often represents opportunity. Ed Keon
represent
I'm proud to represent those hands that labor in this country. Lupe Ontiveros
represent
You do have to be fashionable because you do represent us. If you are part of this troupe, you must look the part at all times. Khare Hawkins
represents
My dancers expect me to deliver because my choreography represents their livelihood. Twyla Tharp
represents speak
No one represents their interests, here or in Mexico. They have to speak up and do it themselves. Jonathan Fox
species happens
What happens to other species also happens to us. Bill Nye
species genome
Living in your genome is the history of our species. Barry Schuler
species
We are stubborn, self-destructive conformists. Any other view of our species is just a self-congratulatory delusion. Michael Crichton
species complexes
We are a complex species to observe Jasmine Guy
species
There are so many species that need help, Chris Servheen
species
There are many gull species in the world. This one is noticeably different from any gull we have in Vermont. Bryan Pfeiffer
species percent
99.99 percent of all species that have ever lived are no longer with us. Bill Bryson
species asks fewer
The fewer species there are and the fewer species we know about, the fewer questions we even know to ask. Lynn Margulis
stones trouble burden
If you tell your troubles to God, you put them into the grave; they will never rise again when you have committed them to Him. If you roll your burden anywhere else, it will roll back again like the stone of Sisyphus. Charles Spurgeon
stones today ends
I keep telling you the future isn't set in stone. It's not all decided yet. The future is just what's down the road we decided to walk on today. You can change roads anytime. And that changes where you end up. Catherine Ryan Hyde
stones may antiques
I may be an antique like the Stones, but antiques are valuable. Billy Joel
stones lists clay
The original lists were probably carved in stone and represented longer periods of time. They contained things like 'Get More Clay. Make Better Oven.' David Viscott
stones rolling these-days
These days, the Rolling Stones still have an edge, but that fangs-out ferocity has mellowed considerably. Diablo Cody
stones heavy ifs
If one's conscience be dead as a stone, it is as heavy too. Edwin Hubbel Chapin
stones next temples
The Temple will not be completed until every living stone is there. And then what? The next thing will be that which our Masonic friends make so much of, and which we make so much of namely: the glorification of the temple. Charles Taze Russell
stones builder corners
The stone that the builder refused shall be the head corner stone. Bob Marley
stones gigs odd
The Stones always tried to do the odd smaller gig when they could. Bill Wyman
tools good-times all-time
All times are good time for those who know how to work and have the tools to do so. Carlos Slim
tools said pins
Nobody's ever said that pins are a tool of diplomacy. Madeleine Albright
tools levels littles
No tools have yet been met with in any of the gravels occurring at the higher levels of the valley of the Seine; but no importance can be attached to this negative fact, as so little search has yet been made for them. Charles Lyell
tools defeated ifs
If I couldn't do it, then I'd be defeated. I've got the tools to do it. I never did question my tools. Billy Higgins
tools materials
Money is neither a material to work upon nor a tool to work with. David Ricardo
tools use digital
Digital brand integration is part of the evolution of product placement. It's simply another tool marketers use to get products integrated into shows. If you can put it in a package, we can put it in a show. David Brenner
tools fool worship
Only fools worship their tools Dee Hock
tools want needs
Sometimes I want to work with a DP, sometimes I want to work myself. I go to 35mm, 16mm, it's all the same, but it depends on what you want to tell and what are the tools you need. Agnes Varda
tools management obstacles
The budget evolved from a management tool into an obstacle to management. Charles Edwards
various
I had no knowledge of the various steps involved in the game balls and the process that happened between when they were prepared and went to the officials and went to the game. So, I've learned a lot about that. Bill Belichick
various
Our party may have swung too far right at various times. Ed Gillespie
various
Each one of us interprets various stimuli according to our own personal sensibility. Stefano Gabbana
various
I've been asked to do various types of cruises. John Oates
various views
We will be considering the views of the various stakeholders. Kevin Hall
various
You had various fiefdoms established in the contracting process. Steve Ellis
various
All the various discussions are going on with all the different parties. Keith McKeown
various rulers
Consider England. Within a few score years how many unsettling changes in religion has the whole kingdom made, according to the change of its rulers, in the various religions which they embraced. Roger Williams