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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
baseball growing-up book
I didnt really grow up a comic book fanatic. I was a big baseball player, and my passion in life, in third grade, was collecting baseball cards. That was my childhood thing. Alan Ritchson
baseball kids player
I wanted to be a baseball player, naturally, but I wasn't good enough. I didn't know what I was going to do with my life. I just had a kind of energy, I was a fairly happy kid. Al Pacino
based behalf business customers decisions field includes line operating personnel regional responsibility restaurant ultimately
We want the line -- which for McDonald's includes our divisional and regional staffs, owner/operators and restaurant personnel -- to make decisions on behalf of customers based on field operating needs. The line ultimately has responsibility and accountability for our business success, Jack Greenberg
base fabulous fan football great
We want to see football in Ottawa. It's a great fan base and has some fabulous potential. But having said that, there's also reality. Ken Hildahl
baseball fun missing
If you're not having fun in baseball, you miss the point of everything. Chris Chambliss
baseball gone home-run
Back, back, back, back... Gone! Chris Berman
baseball hate yankees
Here at NBC there is just one more reason to hate the Yankees. Chet Huntley
baseball school games
I'm a very competitive person, whether it's school, baseball or even playing video games. David Price
baseball winning player
My goal on Earth is not to win a World Series or be the best baseball player who ever lived. That simply is not up to me because I have to wait and see if it is part of the Lord's plan. My goal is to follow the Lord and what he wants me to do so that someday I may enter His kingdom and receive everlasting life. David Murphy
breathing wife missing
You might, from your appearance, be the wife of Lucifer,” said Miss Pross, in her breathing. “Nevertheless, you shall not get the better of me. I am an Englishwoman. Charles Dickens
breathing conscious guided learn simple
We want them to learn simple things that are relaxing, like conscious breathing and guided imagery, which are antidotes to anxiety. Peggy Brown
breathing chemistry court good great run stuck together
We stuck to the basics. They have really good chemistry on the court and were able to put together a great run and get a little breathing room. Mark Capasso
breathing blue life-and-death
Whenever I feel blue, I start breathing again. L. Frank Baum
breathing ideas air
Ah, good conversation - there's nothing like it, is there? The air of ideas is the only air worth breathing. Edith Wharton
breathing finishing
I like finishing a movie and having this living, breathing thing. Dean Cain
breathing wings conspirators
Im a former, living, breathing, right-wing conspirator. David Brock
breathing necks bags
The prisoners for better security against conversation shall have a canvas bag put over the head of each and tied around the neck, with a holes for proper breathing and eating, but not seeing. Edwin M. Stanton
breathing building lead less pressure space title until
We have some breathing space which is great. There is less pressure on us now. We just need to keep building on our lead until the title is secure. Felix Magath
eating used fishes
I still haven't quite got used to eating live fish. David Mitchell
eating flavor pleasure
The pleasure of eating is not in the costly flavor but in yourself. Horace
eating horrible turn
We wanted to turn around their eating habits. They have horrible eating habits. Sylvia Forster
eating nutritionist eating-food
I'm completely changing my diet. My nutritionist recommends I must now stop eating food I have already eliminated. Bob Saget
eating-and-drinking digestion meals
Unquiet meals make ill digestions. William Shakespeare
eating foods fruits neglected people vegetables
Vegetables and fruits are the most neglected foods in the diet. We need to get people back to eating real food, not foods in a package. Luise Light
eating grew lots outweigh pros requires
I grew up doing gymnastics. It requires discipline, eating right, getting sleep, lots of sacrifice. But the pros outweigh the sacrifice. Kacy Catanzaro
eating great nice people touch tweet
I get Twitter, and think it's a great way to keep it in touch, but I don't do it a lot. I hate reading when people tweet about what you're eating or who they are out with, but it's a nice way to keep in touch with people. Tristan MacManus
eating reason solo
In their palate alone is their reason of existence. [Lat., In solo vivendi causa palata est.] Juvenal
half linux firsts
I was Computer Shopper's linux columnist for more than half a decade, from the late 90s onwards. Yes, I know about Linux. (My first review of a Linux distro in the press was published in late 1996.) Charles Stross
half empty gods-will
If I empty out half of my life, God can only fill half...God will fill as much of us as we allow Him to fill. Aiden Wilson Tozer
half safe matter
There are many different kinds of radioactive waste and each has its own half-life so, just to be on the safe side and to simplify matters, I base my calculations on the worst one and that's plutonium. David R. Brower
half intensity played second slow
We started slow today. In the second half we played with better intensity than we did in the first half. Linda Flohr
halfway michigan respecting seven state ten
We are at the turn, we are halfway around the track. It's just about respecting Michigan State and approaching like we have the other seven (Big Ten games). Kristy Curry
halftime hard played struggled
We struggled a little and they made it very hard to penetrate the middle. We made some adjustments at halftime and played better. Jim Mott
half pulled second
We started off slow, ... but in the second half we really pulled away. Robert Bates
half missing three top
We started each half missing a wide-open lay-up, and that kind of set the tone. My top three scorers couldn't find the basket. Dean Montzingo
half period second spent team wears
We spent the whole second period in the box. It wears half the team down. We can't be doing that. It kills us. Jeff Carter
heights potential reach
I'd like to keep going, to keep exploring. It's like anything else there's no way you can reach any kind heights or potential in your first film. Pia Zadora
heights
It always comes down to times, heights and distances. Lon Carter
heights sure
Heights make my feet tingle; not sure if that is a phobia, but it isn't the greatest feeling. Charlie Rowe
heights jackson people queens streets taking walking ways york
Queens is a part of New York that a lot of people don't go to and really should. Walking down the streets in Jackson Heights is in many ways like taking a world tour. Nathan Lump
heights people reached town
We've reached heights that people in this town have never seen. Jeff Pyle
heights rather
I'd rather see new heights when I'm 65. Robert G. Allen
jet main next office send shut talked weeks
We've all talked about it. Our main office would have to send temps, or it would shut down. I wouldn't give my two weeks notice. Who cares? You are a multimillionaire on the next jet to the Bahamas. Chris Taylor
jets light market players several trying wants
We have no idea how the market for very light jets will look in 25 years from now. There are several players trying to get into this market, but we really don't know what the market wants yet. Richard Aboulafia
jet realized surf
I realized that a surf trip on a jet can be like a road trip. If you see a road you want to turn down, you can just go there. Nick Woodman
jets men peter qualified
Peter Rodrick was one of only around 4,000 men in the world qualified to land jets on a carrier after dark. Stephen Rodrick
jets lead mistakes opportunity sitting start team turn
One of the big mistakes a team can make is get a one or two-goal lead and start sitting back ... while the other team has the opportunity to turn on the jets offensively and put some pucks in the net. We didn't want that. Mike Serba
jet kiss son
I'm a limousine ridin', jet flyin', kiss stealin', wheelin' dealin' son of a gun. WOOOO!! Ric Flair
jet picture several
For several years before that, I had a picture of the jet on the mirror. I used to look at it while I shaved. Bruton Smith
jet morning wake
Typically, I'll wake up at 4:30 in the morning. It's just the continual jet lag residue, just weird sleeping hours. Ben Mendelsohn
jets
I also think the Jets would go after Terrell Owens . Peter King
oxygen use muscles
Muscles do not use oxygen at a constant rate. August Krogh
oxygen regulation trustworthy
The absorption of oxygen and the elimination of carbon dioxide in the lungs take place by diffusion alone. There is no trustworthy evidence of any regulation of this process on the part of the organism. August Krogh
oxygen bunnies hunger
If you don't participate, you're just taking up oxygen. (Bunny) Life is a banquet. Approach it with hunger. (Chuck) Deb Caletti
oxygen hyperbole johnson
Hyperbole was to Lyndon Johnson what oxygen is to life. Bill Moyers
oxygen water brain
A drop of water is not immortal; it can be resolved into oxygen and hydrogen. If, therefore, a drop of water were to maintain that it had a quality of aqueousness which would survive its dissolution we should be inclined to be skeptical. In like manner we know that the brain is not immortal... Bertrand Russell
oxygen flames people
The world of derivatives is full of holes that very few people are really aware of. It's like hydrogen and oxygen sitting on the corner waiting for a little flame. Charlie Munger
oxygen friendliness
Relationships are the oxygen of the psyche. Jane Fonda
oxygen iron people
It's you people dying from nothing that are screwed. I got all sorts of neat gadgets waiting for me...oxygen tent, iron lung. Bill Hicks
oxygen looks tents
The rebel is doomed to a violent death. The rest of us can look forward to sedated expiration in a coma inside an oxygen tent, with tubes inserted in every bodily orifice. Edward Abbey
reach struggle stuff
When you struggle to reach for something you don't know, that's where the most interesting stuff is. Herbie Hancock
reach seek
When they want to seek our vote, they know where to reach us, Abner Louima
reaches
You always dream of being part of a show that reaches and thrills an audience. Nikolaj Coster-Waldau
reach time
We are going to take the appropriate time to reach our long-term aspirations. Phil Anderton
reaches technology transcends
Wherever technology reaches its real fulfillment, it transcends into architecture. Ludwig Mies van der Rohe
reaches whose
My heart reaches out to those whose loved ones were lost on MH17. Najib Razak
reached
I want to be able to say on my deathbed that I reached a few people. That would be very nice, just to be able to say that. Evelyn Glennie
reaching vision
Keep your feet on the ground and keep reaching for the stars. Casey Kasem
reach
Of course, it is me being able to reach my goal, Evander Holyfield
sea house theatre
I would like to be going all over the kingdom...and acting everywhere. There's nothing in the world equal to seeing the house rise at you, one sea of delightful faces, one hurrah of applause! Charles Dickens
sea highways
That which,like a sea, threatens to drown you- shall be a highway for your escape Charles Spurgeon
sea suffering needs
Do not wade far out into the dangerous sea of this world's comfort. Take the good that God provides you, but say of it, "It passeth away;" for, indeed, it is but a temporary supply for a temporary need. Never suffer your goods to become your God. Charles Spurgeon
sea world wave
You are something that the whole world is doing just as when the sea has waves on it. Alan Watts
sea play gulls
One of the things that made me want to be an actor more than ever was seeing a Chekhov play, "The Sea Gull," when was 14 in the Bronx. Al Pacino
sea land pirate
But if I hadn't shoved you off the boat back there,you'd be lost at sea now,wouldn't you? We'd all be lost! So thanks to me you're all standing on land." (Pirates, its a good thing they're idiots) Dave Barry
sea fishing rivers
Fishing is boring, unless you catch an actual fish, and then it is disgusting. Dave Barry
sea environmental rising
Canada, more than any nation, will be affected by rising sea levels from global warming. David Suzuki
sea world needs
We need the sea. We need a place to stand and touch and listen - to feel the pusle of the world as the surf rolls in. David R. Brower
sleeping
What we're doing in sleeping is a very old evolutionary phenomenon. Steven Lima
sleeping
He?s driving. I?m sleeping on the way back. Randy Foye
sleeping time totally
He had been sleeping the whole time and was totally disoriented, Dave Adams
sleeping
Sleeping on a lead? I'll let you know tomorrow. Ted Purdy
sleeping
The sleeping disorder, that didn't even come up in trial. I had said something about it, but it had nothing to do with the trial. Keith LeGree
sleeping
It's better than sleeping with the mosquitoes and the bugs. I'll take anything to get there. Carolyn Clark
sleeping
I don't know if he was sleeping or not, ... because he never budged. Joe Torre
sleeping worry
You can't really worry about it. It's nothing that's going to keep me from sleeping at night. Scott Chandler
time son boys
A boy's story is the best that is ever told. Charles Dickens
time fool calendars
Tomorrow! It is a period nowhere to be found in all the registers of time, unless, perchance, in the fool's calendar. Charles Caleb Colton
time all-things
Time is the measurer of all things, but is itself immeasurable, and the grand discloser of all things, but is itself undisclosed. Charles Caleb Colton
time retreat tides
Time ... advances like the slowest tide, but retreats like the swiftest torrent. Charles Caleb Colton
time two black
Time,- that black and narrow isthmus between two eternities. Charles Caleb Colton
time looks one-thing
To look back to antiquity is one thing, to go back to it is another. Charles Caleb Colton
time world overcoming
Time is the most subtle yet the most insatiable of depredators, and by appearing to take nothing is permitted to take all; nor can it be satisfied until it has stolen the world from us, and us from the world. It constantly flies, yet overcomes all things by flight; and although it is the present ally, it will be the future conqueror of death. Charles Caleb Colton
time journey men
Much may be done in those little shreds and patches of time which every day produces, and which most men throw away. Charles Caleb Colton
time opportunity enemy
Time, the cradle of hope.... Wisdom walks before it, opportunity with it, and repentance behind it: he that has made it his friend will have little to fear from his enemies, but he that has made it his enemy will have little to hope from his friends. Charles Caleb Colton