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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
careers chinese connected
I had always thought that I would do something that was connected to music as a career, or possibly Chinese, which was my major. Charles Soule
careers might brilliant
Those of you who are not aware of my brilliant career as a stand up comic, I'm not aware of it either so we might well wonder what we're doing here. Alan Rickman
careers long way
In many ways, my entire graphic novel career was a long diversion. Originally, all I wanted to do was to be an underground cartoonist and maybe bring out a groovy underground mag. Alan Moore
careers long people
During a long career in TV broadcasting, I spent a lot of time contributing to other people's creations. Alan Bradley
careers vision acting
Forget the career, do the work. If you feel what you are doing is on line and you're going someplace and you have a vision and you stay with it, eventually things will happen. Al Pacino
careers laughing three
Al and Tommy and I sharing the biggest laugh because it was predicted by everything we did in the first three or four records in my career. It was predicted in the grooves that we would be here sometime later on down the road. Al Jarreau
career choose exposure females
We want them to have exposure to females who have a career and a family. We want to let them know that you don't have to choose one or the other. Linda Gray
careers theater deeper
I really do love the theater and as you get deeper into your career, it gets harder to carve out the time to do theater. Chris Carmack
careers made wanted
I always knew I wanted to have a good career, so I made it happen. Chord Overstreet
characters daytime kept number relate veterans
We are probably the only show in daytime that has kept characters on. We've had a number of veterans who have been on the show for over 40 years, and how they relate these veterans to their grandchildren is something I think is very real. Chris Goutman
characters friend nice return spend suddenly time
There are characters which you spend a lot of time with, and you get to know, and you feel that -- suddenly it's a friend somewhere. And they are nice to return to. Max Sydow
characters grew influenced obviously pulled
Wherever a writer grew up, they're obviously influenced by that area, and I'm sure their characters are pulled from those experiences. Jim Rash
characters fix hand manuscript partner written
When you've written your characters into a corner, you just hand the manuscript over to your partner and make her fix it. Connie Willis
characters convincing course hard hear normal question scares
I often hear actors say during their interviews: 'I want to play a crazy person, a murderer, or someone who's on edge.' But that question scares me. I mean, of course there are characters I'd like to play, but I can't really say specifically who they are. It's much too hard to play a convincing normal person as it is. Li Bingbing
characters draw
Who doesn't want to draw Batman or Superman? Everyone would like to be able to draw them. I've been really lucky when it comes to the characters that I get to illustrate. Lee Bermejo
characters good great interest people red tricks twist
When you think of a great twist or a red herring or a way of misdirecting the reader, it is good, but you know that they are just tricks at the end of the day, and the way to keep interest is to write characters that people care about. Mark Billingham
characters connect improv machines movies people sort
A lot of times in movies, especially in sequels, the characters become caricatures and just sort of improv machines and joke machines, rather than people you can actually connect to. Hayden Schlossberg
characters erase good name names saying written
When you say the name Gilligan, you know who that is. If a show is good, if it's written well, you should be able to erase the names of the characters saying the lines and still be able to know who said it. If you can't do that, the show will fail. Sherwood Schwartz
ethics be-good respectable
It is hardly respectable to be good nowadays. Edith Sitwell
ethics morality
Science, by itself cannot, supply us with an ethic. Bertrand Russell
ethics conviction concerned
My personal conviction is that science is concerned wholly with truth, not with ethics. Arthur Keith
ethics file individual leader members minority nancy party truce
Minority Leader Nancy Pelosi has never been a party to an ethics truce and has always said that individual members have the right to file a complaint. Jennifer Crider
ethics folks session
We're having an ethics session in the first place because of these folks that got in trouble. Bob Davis
ethics contemplation form
For contemplation is both the highest form of activity (since the intellect is the highest thing in us, and the objects that it apprehends are the highest things that can be known), and also it is the most continuous, because we are more capable of continuous contemplation than we are of any practical activity. Aristotle
ethics great half kids paycheck require send teach
We send them all through McDonald's. It's a great place to teach kids the ethics of working. We require them to put half their paycheck in the bank. Suzy Buchholtz
ethics process question
The question is not about me but about the process and the ethics, Lance Armstrong
ethics morality
Politics is about ethics and morality, openly or not openly. Aleksandar Hemon
fiction flash
I don't do flash fiction. Charles Stross
fiction science-fiction conventions
I'd never been to a science-fiction convention until I became a professional writer. China Mieville
fiction geek fantasy
I'm a science fiction and fantasy geek. China Mieville
fiction fantasy weirdness
One of the things that I love so much about fantasy and science fiction is that the weirdness that it creates is always at its best completely its own end and also metaphorically and symbolically laden. China Mieville
fiction type inferiors
There are no inferior types of fiction, only inferior practitioners of them. David Morrell
fiction plausible
Implausible truth can serve one better than plausible fiction David Mitchell
fiction different process
Fiction and nonfiction, for me, involve very different processes. Chad Harbach
fiction-stories world common
What do my science fiction stories have in common with pornography? Fantasies of an impossibly hospitable world, I'm told. Kurt Vonnegut
fiction narrative moments
Dialogue in fiction should be reserved for the culminating moments and regarded as the spray into which the great wave of narrative breaks in curving towards the watcher on the shore. Edith Wharton
novels
I started writing juvenile novels around 1985. I never really thought of it as a career, but more as a way to make a living. Natsuo Kirino
novels plot
I don't plot my novels - I move along with my characters. Ellen Potter
novels series york
'The Mortal Instruments' is based on a series of novels by Cassandra Clare; it has been a New York Times bestseller, so it is pretty popular. Godfrey Gao
novels poems tales
On that other novels followed: but I still wrote fairy tales and dreamy poems of another world. Laurence Housman
novels time wholly
The novel that's contemporary in the sense of being wholly 'of now' is an impossibility, if only because novels may take years to write, so the 'now' with which they begin will be defunct by the time they're finished. Graham Swift
novels truth
Many novels and modern publications are corrupters of morals or distorters of truth. Ezra Taft Benson
novels people poem straight totally
People are so used to reading novels now, they just read a poem straight through to get the meaning. And that's something totally different from the slow way you read something if it's a tune; which to me a poem has to be. Alice Oswald
novels several tv wrote
My first novel, 'You Must be Sisters,' was started in Pakistan. I've wrote several novels and a TV drama set or partly-set there. Deborah Moggach
novels people physical
I find screenplays easy to write, my novels being very visual. You see what people look like. The physical action is described. John Irving
plot lucky
I'm one of the lucky writers: plots come easily to me Caroline B. Cooney
plot storytelling shows
Anything that happens on any show is a plot contrivance because that's just storytelling. Bryan Fuller
plot shapes divinity
Rashly, And praised be rashness for it--let us know, Our indiscretion sometime serves us well When our deep plots do pall, and that should learn us There's a divinity that shapes our ends, Rough-hew them how we will William Shakespeare
plot cliche generic
The cliches are that it's the most generic Starsky and Hutch plot you can find. Ben Stiller
plot communist buried
Show me where Stalin is buried and I'll show you a Communist Plot. Edgar Bergen
plot hiding subtle
The more subtle and elegant you are in hiding your plot points, the better you are as a writer. Billy Wilder
plot dames christie
I learned everything I know about plot from Dame Agatha (Christie). Connie Willis
plot relationship
A loving mother-son relationship is always a plot or outwitting of some kind. 'Don't tell anyone, but...' my mother was always saying to me - when I wasn't saying it to her. Walter Kirn
plotting prop rewriting studio tim
Tim Conway was a little different from the rest. He was always in the back of the studio building something with the prop man, rewriting his lines, or plotting our demise. Vicki Lawrence
public-trust
I have never, not once, violated my public trust. Alan Mollohan
public
Where there is muck to be raked, it must be raked,and the public must know of it, that it may mete out justice.... S. Hughes
publicity enough good-enough
If my work was good enough, I would never have to do publicity. David Duchovny
publicity
Americans understand better than the Europeans and the English that any publicity is good. Carl Andre
public-opinion found ministers
I know where there is more wisdom than is found in Napoleon, Voltaire, or all the ministers present and to come - in public opinion. Charles Maurice de Talleyrand
public
When times are tough, public employees should have to make the same sacrifices as everyone else. Robert Reich
public
Public employees should have the right to bargain for better wages and working conditions, just like all employees do. Robert Reich
public
My personal style and public style are very different. When I go out, I play dress up. Sharon Stone
publicity obituary
There's no bad publicity except an obituary. Brendan Behan
realities
Mexico is a mosaic of different realities and beauties. Enrique Pena Nieto
realities writer
There are some rougher realities about being a writer in Montana, Kim Anderson
realities
I am grateful to journalism for waking me up to the realities of the world. Eduardo Galeano
realities reflect strategic
does not reflect the strategic realities of today. Donald Rumsfeld
reinforce
Commercialization of assets off the planet would mutually reinforce the growth of interplanetary communication. Vint Cerf
reinforce
I try to be as thoughtful as I can about everything that comes out of my mouth and not reinforce sexism. Hari Kondabolu
reinforcement mutation behavior
We have seen that in certain respects operant reinforcement resembles the natural selection of evolutionary theory. Just as genetic characteristics which arise as mutations are selected or discarded by their consequences, so novel forms of behavior are selected or discarded through reinforcement. B. F. Skinner
reinforcement facts behavior
The strengthening of behavior which results from reinforcement is appropriately called 'conditioning'. In operant conditioning we 'strengthen' an operant in the sense of making a response more probable or, in actual fact, more frequent. B. F. Skinner
reinforce
Because negotiations are ongoing, we have no comment. I want to reinforce that we are not done. Bob Combs
relationship believe two
I don't want to be your other half. I believe that one and one make two. Alanis Morissette
relationship honesty wife
Marriage requires searing honesty at all costs. I learned that from my third wife. Alan Arkin
relationship leadership responsibility
We treat employees as a member of the family. If management take the risk of hiring them, we have to take the responsibility for them. Akio Morita
relationship sex passion
Hugh and I have been together for so long that in order to arouse extraordinary passion, we need to engage in physical combat. Once, he hit me on the back of the head with a broken wineglass, and I fell to the floor pretending to be unconscious. That was romantic, or would have been had he rushed to my side rather than stepping over my body to fetch the dustpan. David Sedaris
relationship girl realizing
I'd had a relationship with a French girl, a Japanese girl, an American girl, a Filippina and she was there all the time - a Lancashire girl. I thought: 'It's a Lancashire girl I was looking for. Why didn't I realize it? David Thewlis
relationship sex opposites
To succeed with the opposite sex, tell her you're impotent. She can't wait to disprove it. Cary Grant
relationship
Where to start? ... This has been a long, love-hate relationship between myself and the French. Lance Armstrong
relationship voice scare
I care," he said in a trembling voice. "I care so much that I do not know how to tell you without it seeming inconsequential compared to how I feel. Even if I am distant at times and seem as if I do not want to be with you, it is only because this scares me, too. Aimee Carter
relationship needs given
You've given me the best of you, but now I need the rest of you. Billy Joel
stories wonderful marley
Marley was dead, to begin with ... This must be distintly understood, or nothing wonderful can come of the story I am going to relate. Charles Dickens
stories ends middle
The point about a great story is that it's got a beginning, a middle and end. Alan Rickman
stories needs thanks
It is an ancient need to be told stories. But the story needs a great storyteller. Thanks for all of it, Jo. Alan Rickman
stories left
I like it when stories are left open. Alan Rickman
stories imaginary
This is an IMAGINARY STORY...aren't they all? Alan Moore
stories
Everybody has their story to tell. Alan Moore
stories storytelling process
I really love storytelling, and I love the stories as they reveal themselves. It's an incredibly nourishing process; it's probably the closest I come to having a religion. Alan Ball
stories
Our stories are the tellers of us. Chris Cleave
stories
We cannot choose where to start and stop. Our stories are the tellers of us. Chris Cleave
textbooks week pastor
I am a pastor, and I teach and preach the Bible to my congregation every week. But the Bible is not a manufacturer's handbook. Neither is it a science textbook nor a guidebook for public policy. Adam Hamilton
textbooks propaganda soviet
Textbooks are Soviet propaganda. Jerry Falwell
textbooks imf world
I found myself doing extraordinary things that arent in the textbooks. Then the IMF asked the U.S. to please print money. The whole world is now practicing what they have been saying I should not. I decided that God had been on my side and had come to vindicate me. Gideon Gono
textbooks study biochemistry
By the time I was 12 or 13, I was studying biochemistry textbooks. Joshua Lederberg
textbooks
Each others' lives are our best textbooks. Gloria Steinem
textbooks able causes
I am sure it is in the medical textbooks, there are many things that cause immune deficiency and you will find therefore in the South African HIV and AIDS programme, that it will say that part of what we have got to do is to make sure that our health infrastructure, our health system is able to deal adequately with all of the illnesses that are a consequence of AIDS. Thabo Mbeki
textbooks cases written
What do you do with a textbook case when no one's written the textbook? Neal Shusterman
textbooks scientology
I am a writer of the textbooks of scientology. L. Ron Hubbard
thought-provoking house ceilings
When we hear a house has fallen do we ask if the ceiling fell with it? Chinua Achebe
thought-provoking giving headache
Writers don't give prescriptions. They give headaches! Chinua Achebe
thought-provoking
The only thing we have learnt from experience is that we learn nothing from experience. Chinua Achebe
thoughtful long battle
Whether you like the label 'Anthropocene' or not, whether you find the prospect of what it signifies inevitable or appalling (or both), the time has come to address its implications, as these thoughtful, battle-tested authors attempt to do. The time has long since come. David Quammen
thoughts-of-death repose
Death is repose, but the thought of death disturbs all repose. Cesare Pavese
thoughtful decision sticks
I'm very thoughtful, and when I make a decision I usually stick to it. Casey Stoner
thoughtful talking going-away
That is not the best sermon which makes the hearers go away talking to one another and praising the speaker, but which makes them go away thoughtful and serious, and hastening to be alone. William Shakespeare
thoughtful perfect levels
Your Majesty would have a perfect right to strike off his head," said Peridan. "Such an assault as he made puts him on a level with assassins." "It is very true," said Edmund. "But even a traitor may mend. I have known one that did." And he looked very thoughtful. C. S. Lewis
thoughtful thinking psychics
I snuck a look to see how Eric was taking this, and he was staring at me the same way the Monroe vampires had. Thoughtful. Hungry. "That's interesting," he said. "I had a psychic once. It was incredible." "Did the psychic think so? Charlaine Harris
three four finished
In 1980 I finished three or four times in seventh place. Alain Prost
three balls easy
The three-ball is an easy shot if you're uncontested, but when they know you can shoot, it's a lot harder to get off. Chris Copeland
three essentials action
There are three essential factors in all human activity: spirit, materials, and action. Chiang Kai-shek
three kind i-can
I can find only three kinds of business in the Universe: mine, yours, and God's. Byron Katie
three england beats
When you beat Arsenal, they are a good three points. Bryan Robson
three
The other three have really made strides. They're consistently getting better. Bill Wright
three
We've already got three up on the board. Steve Alford
three moments hours
Preferred three hours quicker over one moment late. William Shakespeare
three kind persons
Before repeating something bad about another person, ask yourself these three questions: Is it true? Is it necessary for me to tell it? Is it kind to tell it? Charles L. Allen
traded work
When we traded him, I would say that was probably a lose-lose. It didn't work out well for anyone. Dave Checketts
traded win
I would have traded all that for a win in this game. Ashley Gronewoller
traded
Personally, I don't think I'm going to get traded this year, Barry Zito