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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
aging answers dedicated delay develop extending finding glenn healthful human mechanisms molecular normal paul process proud thereby understand
We are proud to be teaming up with Mr. Glenn and the Glenn Foundation. Like us, Paul is dedicated to finding the molecular answers to the aging process so we can understand the mechanisms of normal aging and develop interventions to delay its onset and decline, thereby extending the healthful years of human life. David Sinclair
aging children follow generation gives guilt heed husbands jokes laugh listened looking louder permission small totally voices women
We are a generation of women that has listened to the much louder voices of parents, teachers, employers, husbands and children while our own voices were small or muffled or totally ignored. Aging Out Loud gives us permission to not only listen to that voice but heed its warnings, laugh at its jokes and follow its directions, without guilt and without looking back. Connie Stevens
aging challenge confront countries europe good relative shape
We're in much better shape to confront the aging challenge than the countries of continental Europe or Japan. But good shape is a relative statement. Richard Jackson
aging nations
As a nation, we have never embraced aging, Denise Lewis
aging embrace hollywood peace pressure supposed wiser work younger
Aging in Hollywood sucks. There's always so much pressure to look way younger than you are, and everyone's watching! I'd like to embrace getting older, because it's kind of inevitable. The different, wiser me, to be at peace with how I look and I'm supposed to look - it's a work in progress. Lisa Vidal
aging define inspires living people stuff
We write about the stuff that inspires us: relationships, traveling, aging and living in general. Those are the things that define people as they are. Scott Terry
aging attention begin care cost essential future general loved pay planning public until
With the onset of the aging demographic revolution, it is essential that the general public begin planning for their future care requirements. Unfortunately, most of us pay little attention to the cost of such care until we or our loved ones need it. Bill Novelli
aging permission knows
Life, the permission to know death. Djuna Barnes
aging myth growing-older
Now is the time to become a myth. Diane von Furstenberg
answers frost chill
We can no longer let the threat of an early frost send a chill of fear throughout a large portion of our workforce. Diversification is the only answer. Alan Autry
answer questions
We want to see if we can coexist. These are questions that no one can effectively answer at this point. Paul Hoolahan
answers want asking
We did that often, asking each other questions whose answers we already knew. Perhaps it was so that we would not ask the other questions, the ones whose answers we did not want to know. Chimamanda Ngozi Adichie
answers demand asks
Why ask a question whose answer would demand ten more questions? David Mitchell
answers might united-states
Will the United States pull the rug on New Zealand? The answer is no. They might polish the lino a bit harder and hope that I execute a rather unseemly glide across it. David Lange
answers would-be why-me
Unfortunately, there's no greater rhyme or reason as to why it would be me. And since there is no answer as to why me, it's not a question I feel really entitled to ask. David Rakoff
answers courageous wonder
Ask courageous questions. Do not be satisfied with superficial answers. Be open to wonder and at the same time subject all claims to knowledge, without exception, to intense skeptical scrutiny. Be aware of human fallibility. Cherish your species and your planet. Carl Sagan
answered believe criteria french-scientist isolated knowledge
One could not have isolated this retrovirus without knowledge of other retroviruses, that's obvious. But I believe we have answered the criteria of isolation. Luc Montagnier
answer gun learned simple smoking tough
The one thing we learned in 2005 is there is no simple answer or smoking gun for this. This is a tough problem. Chuck D.
baby world lasts
Every baby born into the world is a finer one than the last. Charles Dickens
baby philosophy war
A living body is not a fixed thing but a flowing event, like a flame or a whirlpool: the shape alone is stable, for the substance is a stream of energy going in at one end and out at the other. We are particularly and temporarily identifiable wiggles in a stream that enters us in the form of light, heat, air, water, milk, bread, fruit, beer, beef Stroganoff, caviar, and pate de foie gras. It goes out as gas and excrement - and also as semen, babies, talk, politics, commerce, war, poetry, and music. And philosophy. Alan Watts
baby lying believe
The difference between a baby and adult is that a baby believes in everything while the adult doubts everything. Babies also only tell the truth until they learn what a lie is. Alan Watts
baby boys four
I've had to live with women all my life. I grew up with four older sisters, and I was the baby and the only boy. Alan Jackson
baby strong jugs
I'm hooked on my baby's love, there ain't nothing in the jug this strong. Alan Jackson
baby anger kids
In our society leaving baby with Daddy is just one step above leaving the kids to be raised by wolves or apes. Al Roker
baby sorry devils-advocate
Freedom, baby, is never having to say youre sorry. Al Pacino
baby memories past
The little babies are missing their families from their past lives. The babies have old souls and the old souls have to shrink to become little babies. The tears loosen their memories so they can slide away. They cry at the life they have lost, and then they cry at everything they'll forget. Akhil Sharma
baby home wife
My wife and I would be very comfortable having a baby at home or using one of the terrific nurse-midwives at the hospital. Chris Bohjalian
call clear information resources
We want them to have clear information about this subject, and resources to call on. Fred Engh
call effort takes
We want them to call us. It takes a collaborative effort with our partners. Steve McDonald
calling answers levels
The honest answer is more complex. On some level I was sent. Or inspired. Or called. But my calling, such as it was, wasn't a single booming invitation from above (really, is it ever?)... Chris Bohjalian
calling uncomfortable okay
I felt uncomfortable calling myself a writer until I started with 'The New Yorker,' and then I was like, 'Okay, now you can call yourself that. David Sedaris
call number
'Crush' was my first number one on the call sheet. Lucas Till
calling course developed files members prior release sealed
There have been a couple of instances prior to now where members of the House have filed resolutions calling for release of the sealed files which were developed during the course of our committee's investigation. Louis Stokes
call domestic interested whatever
I think I'm interested in these kinds of character dramas, psychological dramas, domestic dramas, whatever you want to call them - comedy dramas. Lisa Cholodenko
calling came consider education later life theater
Film is something that came later into my life. I had a Jesuit education, and I consider acting and the theater as kind of a calling - a vocation. Michael Moriarty
calling reason categories
I see no reason for calling my work poetry except that there is no other category in which to put it. Marianne Moore
employment
The pleasantness of an employment does not always evince its propriety. Jane Austen
employment good improving pointing seeing series solid
We are seeing a series of good indicators pointing to solid recovery: improving production, improving exports, improving employment and improving spending. Masaaki Kanno
employment lands supply
When you take out the lands that are encumbered or don't have servicing, you come down to an 11.8-year supply of employment lands, John Waller
employment occupation principles
The great subverter of Pyrrhonism or the excessive principles of scepticism is action, and employment, and the occupations of common life. David Hume
employment discrimination should
Liberals say we should end employment discrimination. I say we should end employment. Bob Black
employment goes health insurance lose portable work
We should work to de-link health insurance from employment so if you lose your job, your health insurance goes with you and it is personal, portable and affordable. Ted Cruz
employment economics achieve
We cannot hope to achieve full employment and sustain it until we have mastered inflation. Denis Healey
employment hired hopeful language lawyers model others
We have hired employment lawyers to come up with model language for contracts. We are hopeful this will be emulated by others in the industry. Karina Litvack
employment framework hold party plenty policy power prosperity whatever
We need a policy framework which will hold whatever party is in power so there will be peace, prosperity and plenty of employment opportunities, Ranil Wickremesinghe
experts
I'm not a marriage expert, quite clearly. Cathy Freeman
experts professors respect
We respect not only professors and experts but also technologists who have their own inventions, Wen Jiabao
experts form good improve moves
When we are on the set, there are always experts there to choreograph the moves and improve your form so you look good for the camera. Thuy Trang
experts agree forecasts
When all the experts and forecasts agree, something else is going to happen Bob Farrell
experts field help looking whenever
Whenever you're looking at something like this, it's important to get as many experts in the field to help you. Carol Sanders
experts looks may
I look at myself more as a storyteller than a screenwriter, as pretentious as that may sound, but that's what really attracts me to TED Talks. For me, the really effective ones are being presented by expert storytellers. Damon Lindelof
experts finance personal-finance
I don't really consider myself to be a personal finance expert compared with some others. There are quite a few that know a lot more than I do. Ben Stein
experts want
I'm not an expert, but I want to be. Ben Nicholson
experts heard higher job numbers package stimulus today
We heard much higher numbers today of the stimulus package from our two experts than I anticipated we would hear. In other words, if you're going to do something, it better be something significant enough to get the job done. Charles Grassley
growing-up women thinking
... the woman who grows up with the idea that she is simply to be an amiable animal, to be caressed and coaxed, is invariably a bitterly disappointed woman. A game of chess will cure such a conceit forever. The woman that knows the most, thinks the most, feels the most, is the most. Intellectual affection is the only lasting love. Love that has a game of chess in it can checkmate any man and solve the problem of life. Charles Dickens
growing-up people needs
Many people never grow up. They stay all their lives with a passionate need for external authority and guidance, pretending not to trust their own judgment. Alan Watts
growing-up book comic
I didn't really grow up a comic book fanatic. Alan Ritchson
growing late critique
A lot of the critique of our growing mechanization was actually at its strongest, and arguably at its most perceptive, during the late '60s. Alan Moore
growing bigs distrust
There's been a growing dissatisfaction and distrust with the conventional publishing industry, in that you tend to have a lot of formerly reputable imprints now owned by big conglomerates. Alan Moore
growing-up school boys
Growing up in the Boroughs, I thought I must be the cleverest boy in the world, an illusion that I was able to maintain until I got to the grammar school. Alan Moore
growing-up hands world
A world grows up around me. Am I shaping it, or do its predetermined contours guide my hand? Alan Moore
growing-up tired talking
Growing up in a Canadian household that was more British than Big Ben, I dreamed of flying to England myself and visiting the places my family never tired of talking about. I always woke up before the plane landed. Alan Bradley
growing middle standing-still
Either you're growing or you're decaying; there's no middle ground. If you're standing still, you're decaying. Alan Arkin
healthcare debate easy
It's easy to get distracted by the vaudevillian aspects of the healthcare debate. Carl Hiaasen
healthcare coverage
I am all for using business - public and private - to expand healthcare coverage. Bob McDonnell
healthcare including parenthood planned poor provides services women
While Planned Parenthood provides abortions at some of their clinics, it also provides healthcare services for poor women, including checkups, mammograms, cervical cancer screenings and contraceptives. Juan Williams
healthcare cigarette fried-food
Now that healthcare is guaranteed, I'm frying everything I eat. Fried food and cigarettes. Craig Ferguson
healthcare looking time
Because of the long-term complications of cocaine use, we are looking at a healthcare time bomb, O. Henry
healthcare kind wanted
I always kind of wanted to go into healthcare. Ann Marie Buerkle
healthcare horror shows
Our healthcare is a horror show. Donald Trump
healthcare plan time
He has misrepresented my healthcare plan time after time after time, and I called him on it, Bill Bradley
healthcare healthy numbers provide stay
We really need them to stay there because the numbers over there are ridiculous. It's important that they stay healthy to provide healthcare there. Grier Stanley
helping-someone achievement saving
Helping someone come to a saving knowledge of Christ is the greatest achievement possible. Charles Stanley
helping conservation protect
The more you know about a species, the more you understand about how better to help protect them. Alan Clark
help understand
We want them to understand we're here to help and do everything we can, Mike Harris
help organize
We want to see how we can help organize the transfer. Javier Solana
helping-others names way
Helping others is a question of being genuine and projecting that genuineness to others. This way of being doesn't have to have a title or a name particularly. It is just being ultimately decent. Chogyam Trungpa
helping conspiracy crime
Prosecutors tend to love conspiracy charges because the rules of evidence are easier, meaning you can get more in to help prove a crime. David Shuster
helping-someone stories sometimes
I love helping someone else tell their story, but I like being the storyteller sometimes. David Schwimmer
helping ability
All of those measures of relationships that you have in your life help feed your and inform your ability to act. David Koechner
helping help-me help-yourself
Seriously? You won’t help me?” “Help yourself get killed? No, I won’t. Dave Barry
information asks
I only ask for information. Charles Dickens
information
We want to see how much information is forthcoming between now and the 7th. Charles Schumer
information increase intervention
My sustenance is information. My interventions are hidden. I increase as I learn. I compute, so I am. China Mieville
information seeking
We are always seeking new and better information. Mayor Barse
information points seen start worrying
We've already had some very worrying points of information which could have seen the start of the correction. Richard Davidson
information light obtain whether
Where they lived, how big they were, how much light they emitted, whether they even existed, we weren't sure. What we've done, we think, is obtain the first information about these stars. Alexander Kashlinsky
information listening ought truly
Where's our majority, they're the one's who ought to be here listening to this. This is information we really and truly ought to be concentrating on. Bill Summers
information knowledge lost wisdom
Where is wisdom we have lost in knowledge? Where is the knowledge we have lost in information? T. S. Eliot
information you-like-it ownership
When you post something, when you text something, you lose ownership of it when you hit enter or send. Who you send it to, where you post it, they take ownership of that information whether you like it or not. Mark Cuban
marketing phrases idiot
That pompous phrase (graphic novel) was thought up by some idiot in the marketing department of DC. I prefer to call them Big Expensive Comics. Alan Moore
marketing advertising timing
Strategy and timing are the Himalayas of marketing. Everything else is the Catskills. Al Ries
marketing company ultimate
Marketing is what a company is in business to do. Marketing is a company's ultimate objective. Al Ries
marketing mind building
Marketing is not selling. Marketing is building a brand in the mind of the prospect. Al Ries
marketing cows looks
A branding program should be designed to differentiate your cow from all the other cattle on the range. Even if all the cattle on the range look pretty much alike. Al Ries
marketing world needs
All you need is the best product in the world, the most efficient production in the world and global marketing. Akio Morita
market
We still like the equities market and think the S&P 500 could potentially go through 1300 this week. Henry McVey
marketing advertising products
Marketing is what you do when your product is no good. Edwin Land
marketing coaching good-coaches
I was a pretty good coach and working with marketing was like coaching. Bernard Ebbers
optimistic may adequacy
Our problems may stay, our circumstances may remain, but we know God is in control. We are focused on His adequacy, not our inadequacy. Charles Stanley
optimistic son thinking
"I think the wonderment of seeing my two sons developing makes me incredibly optimistic about human potential. It makes you think: 'My goodness. It's a miracle that's going on here. What could the human race do together?"' David Miliband
optimistic thinking optimism
There's nothing particularly wrong with being more pessimistic than optimistic. Optimism is broad-based, non-detail-oriented thinking; pessimism is detail-oriented thinking. David Rakoff
optimistic space awful
The universe is a pretty big place. If it's just us, seems like an awful waste of space. Carl Sagan
optimistic past mind
For me, the future lives only here in my mind, as thoughts and images, just as the past does, and I love those thoughts and the world that it produces. I am entirely optimistic about the future. Byron Katie
optimistic looks
I look at a woman and I don't see what's wrong with her. I see what's right. Bobbi Brown
optimistic someday empty
Americans are optimists. They hope they'll be wealthy someday - and they're positive they can get one more brushful of paint out of an empty can. Bernard Williams
optimistic men
No man ever threw away life while it was worth keeping. David Hume
optimistic analysts
Analysts have always been overly optimistic. David Dreman
outlook-on-life everyday sometimes
It's your outlook on life that counts. If you take yourself lightly and don't take yourself too seriously, pretty soon you can find the humor in our everyday lives. And sometimes it can be a lifesaver. Betty White
outlook pleased
The outlook for Georgia, I'm pleased to say, is good. George Benson
outlook-on-life people mets
I've had experiences in my life where I've met certain people that have opened up something in me and given me hope and a new outlook on life. Aubrey Plaza
outlook worse
The outlook is worse than we had hoped. Christian Maher
outlook year
The outlook for the remainder of the year is positive. Stuart Murray
outlook surrounds
More uncertainty, however, surrounds the outlook for inflation, Alan Greenspan
outlook practices spirit
My father is an acupuncturist, and the way he practices is very free. For me, he's like an artist. He started to do acupuncture when it wasn't so accepted. His spirit and outlook inspire me. Anna Mouglalis
outlook time worse
I don't walk around chuckling all the time. My outlook is very bleak. It's worse than bleak, it's apocalyptic. Mark Leyner
outlook prove ifs
There's nothing you can't prove if your outlook is only sufficiently limited. Dorothy L. Sayers
security
There is no security for those who seek it outside of themselves. Byron Katie
security
The security of the woman is the security of society. Atifete Jahjaga
security-and-freedom people liberty
People willing to trade their freedom for temporary security deserve neither and will lose both. Benjamin Franklin
security-measures security
Effective security measures do not come cheap. Arlen Specter
security-systems people world
A colleague once told me that the world was full of bad security systems designed by people who read Applied Cryptography Bruce Schneier
security-systems people links
People often represent the weakest link in the security chain and are chronically responsible for the failure of security systems. Bruce Schneier
security
Security is a concern, ... It is a priority. Alberto Gonzales
security-guards ideas two
Every head turned to see two more security guards appear, each holding a Bagshaw by the back of the neck (which might have been considerably less conspicuous had the Bagshaws not been dressed as chimney sweeps). Kat turned back to Hale. 'The Mary Poppins?' 'Seemed like a good idea at the time. Ally Carter
security
We'd like to have one of them, yeah. You'd always like to have more security and more depth. Neil Callaway
technology hands people
Technology is destructive only in the hands of people who do not realize that they are one and the same process as the universe. Alan Watts
technology civilization goal
...the materialism of modern civilization is paradoxically founded on a hatred of materiality, a goal-oriented desire to obliterate all natural limits through technology, imposing an abstract grid over nature. Alan Watts
technology fit lifestyle
The success of SYNC is another proof point that we are doing just that. We will continue to innovate and expand the capability of SYNC by integrating even more new technologies that fit our customers’ lifestyles. Alan Mulally
technology matter watches
It doesn't matter what the technology is - no one will watch a Peter Greenaway film anyway. Alan Parker
technology fields needs
The computing field is always in need of new cliches. Alan Perlis
technology thinking people
I think it is inevitable that people program poorly. Training will not substantially help matters. We have to learn to live with it. Alan Perlis
technology bird worms
In software systems it is often the early bird that makes the worm. Alan Perlis
technology two benefits
Technology is always a two-edged sword. It will bring in many benefits, but also many disasters. Alan Moore
technology amish kind
I'm remote from most technology to the point that I'm kind of Amish. Alan Moore
wages gains virtue
Sincerely to aspire after virtue, is to gain her; and zealously to labour after her wages, is to receive them. Charles Caleb Colton
wages world pay
Not even in this world does sin pay its servants good wages. Charles Spurgeon
wages praise
Your praises will become your wages. William Shakespeare
wages commodity machinery
But a rise in the wages of labour would not equally affect commodities produced with machinery quickly consumed, and commodities produced with machinery slowly consumed. David Ricardo
wages profit farmers
The farmer and manufacturer can no more live without profit than the labourer without wages. David Ricardo
wages comfort currency
There never has been a time in our history when work was so abundant or when wages were as high, whether measured by the currency in which they are paid or by their power to supply the necessaries and comforts of life. Benjamin Harrison
wages pay salary
Not one of our national officers ever has had a dollar of salary. I retire on full pay! Susan B. Anthony
wages reconstruction workers
While prices of goods continue to rise, American worker's wages remain stagnant. Ed Pastor
wages trends slumps
We are in the midst of a protracted wage slump, ... a troubling trend that is largely going unnoticed by policymakers. Jared Bernstein