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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
allowed available concern consumers dependent fast federal information interpret leverage manage model private sector send soon totally
We want to totally reconfigure this model so that the purchasers have available information before they make a purchase. Our concern is how soon can consumers get the info how soon can NMVTIS get the information. If we're dependent on federal agencies, we're not going to get it as fast as if the private sector is allowed to leverage that info manage it and interpret it and send it back out. David Regan
allowed although clueless far following gigs killer producers resume suddenly
I had done a couple of plays, but I was a clueless boob. 'Cosby' allowed me to have something on my resume that was real and then the producers of 'Guiding Light' let me play a preppy killer just the following month. Suddenly I had two gigs on my resume that made me look like a real actor, although I was far from it. Michael Weatherly
allowed pleasure
The pleasure is in being allowed to play in so many different sandboxes. Julie Andrews
allowed creep necessary
We've allowed those things to creep back. They are not necessary and should not be allowed. Rich McKay
allowed football loan needs
We've allowed him to go out on loan because he needs to play some first-team football, Alan Curbishley
allowed benefits bring business companies services sure
We, U S West, are not allowed to be in the long-distance business today. But we wanted to make sure that we could bring the benefits of services of companies like Qwest to our customers. Sol Trujillo
allowed defense stops
We started to get some defense stops and that allowed us to run. Michael Holton
allowed stuff
We started out well, and then when we made substitutions and allowed them to get stuff going. John Ramunno
allowed double played running slower stopped
We stopped running and played at a slower tempo, which allowed them to sag in and double team. Andrew Booth
becomes causing change dramatic question species stop wonder
Every species becomes extinct; at some point, we will go extinct. The question is, as Homo sapiens, are we going to be able to adapt to the change that we're actually part of? We're causing such dramatic changes to the planet, so yes, you do stop and think, 'I wonder where we're headed.' Louise Leakey
becomes behind difficult hit judge potential
The potential of getting hit from behind is always there. And at night, it becomes so much more difficult to judge the situation. Gary Owens
becomes blessed darkness great himself inevitably liberates mind noble pure
The person blessed with a pure mind is noble and he inevitably becomes great and liberates himself from the darkness of ignorance. Rig Veda
becomes consider dream fair fun game ordinarily people plunder property themselves
Untended property becomes fair game for people out for fun or plunder and even for people who ordinarily would not dream of doing such things and who probably consider themselves law- abiding, E. O. Wilson
becomes boats growth lift market price rising sales tides
Where there's not sales growth in the market at all everything is market share, everything is price and it becomes particularly vicious. There's no rising tides to lift any boats in this market. Sean McAlinden
becomes body high joy kindness quiet rather regard spiritual treat
When you treat yourself with the kindness and high regard that you would give to one of your spiritual heroes, your body becomes the epicenter of quiet joy rather than a battlefield for the ego. Debbie Ford
becomes city katrina orleans population question rebuild
When you think that the population of metropolitan New Orleans before Katrina was 485,000 and it's now 150,000, so two-thirds of the city is gone. The question of how to rebuild becomes very difficult. Reed Kroloff
becomes brings committees freedom lead opposite people pressure stay success
Success brings with it pressure to conform. I always thought that success would lead to freedom, but the opposite is true: more people get involved, and committees make decisions, and it becomes a fight to stay free. Nick Park
becomes begin certain confused event guided happening people processes rational reactions sleep society tend thinking traumatic whenever
Whenever you get a traumatic event happening in society, you tend to see certain reactions to it, such as irritability, depression, confused thinking and sleep problems, ... In that context, rational decision-making becomes very difficult. People tend to begin to let their thought processes be guided by their anxieties. Richard Geist
critical focus stretch winning
We want to see if we can get that done, ... So our focus is winning the first one. This is a very critical two-week stretch for us. Tony Dungy
critical stage
We are at a very critical stage in our negotiations, John Broughton
critical people time
We're in that critical time that people can be rescued, ... If we don't get out thereto and do it now, then they're going to die. Pat Sullivan
critical-spirit habit critical
Make it your habit not to be critical about small things. Edward Everett Hale
critical literally room
We have no room literally to spare. Every game, every day is critical to us. Dave Wannstedt
critical injuries minor multiple serious
We have multiple critical injuries and multiple serious injuries and some minor injuries, Willie Williams
critical department fatal suffers whenever
Whenever the department suffers a fatal fire, we take a constructive, critical look at the event. Thomas Galvin
critical our-lives anything-is-possible
Health is the most critical thing in our life. With your health anything is possible, without it you can't do anything. Bill Walton
critical people reporters time truth war whining
While many people think that we as reporters are whining and that this is a time of war, we are really the conveyors of truth in a very critical time and people need to know that truth. Judd Rose
crucial files finds might organized
For one person, organized files might be a crucial tool for creativity; another person finds inspiration in random juxtapositions. Gretchen Rubin
crucial everybody groove hit walker
Walker hit crucial shots. She got everybody going. She ignited us offensively and defensively. We were able to find a groove and get focused. Wendee Saintsing
crucial foul people possible simply themselves
In order to get what you want, you must first decide what you want. Most people really foul up at this crucial first step because they simply can't see how it's possible to get what they want, so they don't even let themselves want it. Jack Canfield
crucial figure good movies
Making a movie is so hard, you'd better make movies about something you really know about. And even more, it's really good to make movies about things you need to figure out for yourself, so you're driven the whole way through. It's going to make things more crucial for you. Mike Mills
crucial might scientists
It is crucial for scientists to be willing to be wrong; otherwise, you might not do the most important experiments, or you may ignore your most important findings. Stanley B. Prusiner
crucial marketing plays role success tricks
I feel luck plays a vey crucial role in determining the success of the book. Marketing a book is also very important. You need to try all tricks in the trade. Ashwin Sanghi
crucial level matter per prestige tv whatever
Whatever I do, it's crucial to me that I give it 100 per cent. It doesn't matter if it's a short film, stage, theatre, TV or blockbuster. It doesn't matter what level of budget or prestige it is. Ewen Bremner
crucial goal match mistake perfect poised poke rather score seem toe
When the match is poised at 1-1, you know one mistake could be crucial and there is an understandable nervousness. We seem to want to score the perfect goal when I'd much rather see us get scruffy ones - a toe poke or a ricochet. Tony Mowbray
crucial midfield numbers oscar signed strengthen
We have signed Oscar to strengthen numbers in the crucial midfield area. Sam Allardyce
defenders
Best defender I have played against? Carles Puyol Cesc Fabregas
defended playoff positive time
The positive was we defended down the stretch. That's what we're going to have to do when playoff time comes. Flip Saunders
defend prepared ready stand
We are prepared to do that, and we stand ready to defend our rights, Rafael Ramirez
defending good stand texans texas
We stand with other Texans in defending Texas as a good place to live. Ed Sills
defend ensure open ready stand steps
We stand ready to vigorously defend the NAFTA and we will take all steps open to us to ensure it is respected. Jim Peterson
defend given iraqi manage means ourselves people prove provided security support
We want to prove to the Iraqi people and the world that we are in charge. We can manage our own security and can defend ourselves provided we are given the means and support to do that. Hoshiyar Zebari
defend happy hard hold nick teams
We're going to play hard and we're going to defend you. We were happy to hold Nick to 14 points, which not many teams are going to be able to do because he's a big-time player. Dwight Freeman
defend difference half harder
What a difference she makes for their team. She can do so many things with the ball. It makes it a lot harder to defend them at half court. Tom Megyesi
defend people plays
Working the game, you always have plays people don?t like. That is just part of it. But this other thing, it is not true, and that is the thing I will defend myself on. Terry Porter
power overcoming cowardice
That cowardice is incorrigible which the love of power cannot overcome. Charles Caleb Colton
powerful weak said
The worst thing that can be said of the most powerful is that they can take your life; but the same can be said of the most weak. Charles Caleb Colton
power two age
There are three kinds of power,--wealth, strength, and talent; but as old age always weakens, often destroys, the two latter, the aged are induced to cling with the greater avidity to the former. Charles Caleb Colton
powerful forgiving easy
It is more easy to forgive the weak who have injured us than the powerful whom we have injured. Charles Caleb Colton
powerful heaven goddess
We make a goddess of Fortune ... and place her in the highest heaven. But it is not fortune that is exalted and powerful, but we ourselves that are abject and weak. Charles Caleb Colton
powerful heart vanity
Vanity finds in self-love so powerful an ally that it storms, as it were, by a coup de main,, the citadel of our heads, where, having blinded the two watchmen, it readily descends into the heart. Charles Caleb Colton
powerful lying believe
One of Satan's most deceptive and powerful ways of defeating us is to get us to believe a lie. And the biggest lie is that there are no consequences to our own doing. Satan will give you whatever you ask for if it will lead you where he ultimately wants you. Charles Stanley
powerful evil spirit
We declare, upon Scriptural authority, that the human will is so desperately set on mischief, so depraved, and so inclined to everything that is evil, and so disinclined to everything that is good, that without the powerful, supernatural, irresistible influence of the Holy Spirit, no human will ever be constrained towards Christ. Charles Spurgeon
powerful church christ
In proportion as a church is holy, in that proportion will its testimony for Christ be powerful. Charles Spurgeon
production
We're getting production from different people. They're working well as a team. Ed Miller
production recording step
The production and recording is a big step up. Grayson White
production
We are not getting the production offensively for what we need to be successful. Frank Robinson
production value videos youtube
The production value of YouTube videos is not there. Dana Brunetti
production
Hopefully, they'll be back in production very soon, Rick Perry
production
I wouldn't want to say how much production has been slowed, but it has been slowed. Definitely. Mark Klein
production step
When you get opportunities, you have to step up and take them. We need production from our bench. Dee Brown
production ramp resides technology
We must be able to ramp up production and migrate the technology to more models, but we can't do that if the know-how resides abroad. Phil Martens
production shooting
We are shooting for resuming the production in mid-September. H. Hart
products quarter talked
There are some big inventories out there. The new products that they have talked about aren't out for another quarter or so. So it's probably going to be more of the same for some time. Bob Turner
products
It is necessary that I am viewed as a product. I am a product. Ayumi Hamasaki
products putting quality shelves sure
We want to make sure we're only putting safe, quality products on our shelves for our customers. Karen Burk
products
We got to this point by constantly perfecting our products. Connie Sellecca
products
one of the better products we've launched in a long time. Jerry Yang
products shipping uncertain
I am uncertain about shipping our products on time. Fazlul Haque
products showcase
Basically, we do it to showcase our products to celebrities. Deanna Anderson
products providers sell service unless
More and more of the products are going to become 'carrier Ethernet,' because manufacturers aren't going to be able to sell them to service providers unless they have all these features. Michael Howard
products
You have to be a product of the product. Anthony Powell
states secretary
I loved what I did. I could've been secretary of state for ever. Madeleine Albright
states evident secretary
I loved being Secretary of State, that's probably evident to everyone who watched me. Madeleine Albright
states barometer interest
...interest is the barometer of the state... David Hume
states hyperbole constant
I live in a constant state of hyperbole. Eden Sher
states senators productive
I was very productive as a senator for my state. Carol Moseley Braun
states united
I have not broken the laws of the United States or the laws of the Dominican Republic. Sammy Sosa
states loses
Better lose me than lose a state. Susan B. Anthony
states subjects susceptibility
writers do not find subjects: subjects find them. There is not so much a search as a state of open susceptibility. Elizabeth Bowen
states united wants
Nobody wants to put the creditworthiness of the United States in jeopardy. Nobody wants to see the United States default. So we've got to seize this moment, and we have to seize it soon. Barack Obama
technology hands people
Technology is destructive only in the hands of people who do not realize that they are one and the same process as the universe. Alan Watts
technology civilization goal
...the materialism of modern civilization is paradoxically founded on a hatred of materiality, a goal-oriented desire to obliterate all natural limits through technology, imposing an abstract grid over nature. Alan Watts
technology fit lifestyle
The success of SYNC is another proof point that we are doing just that. We will continue to innovate and expand the capability of SYNC by integrating even more new technologies that fit our customers’ lifestyles. Alan Mulally
technology matter watches
It doesn't matter what the technology is - no one will watch a Peter Greenaway film anyway. Alan Parker
technology fields needs
The computing field is always in need of new cliches. Alan Perlis
technology thinking people
I think it is inevitable that people program poorly. Training will not substantially help matters. We have to learn to live with it. Alan Perlis
technology bird worms
In software systems it is often the early bird that makes the worm. Alan Perlis
technology two benefits
Technology is always a two-edged sword. It will bring in many benefits, but also many disasters. Alan Moore
technology amish kind
I'm remote from most technology to the point that I'm kind of Amish. Alan Moore
united-states significant congress
Madam Speaker, before being elected to Congress, I ran a manufacturing business that did a significant percentage of our sales outside the United States. Chris Chocola
united-states lines problem
The bottom line is this. When it comes to preventing violent extremism and terrorism in the United States, Muslim Americans are not part of the problem, you're part of the solution. Denis McDonough
united-states states united
Episcopalians are pretty thin on the ground in the central United States. Charlaine Harris
united-states immigrants nations
The United States is historically a nation of immigrants. Charles Rangel
united-states may constitution
I will, to the best of my ability, preserve, protect and defend the Constitution of the United States. It is not the Constitution as I would like to have it, but as it is, that is to be defended. The Constitution will not be preserved & defended until it is enforced & obeyed in every part of every one of the United States. It must be so respected, obeyed, enforced and defended, and let the grass grow where it may. Abraham Lincoln
united-states folks collapse
You can't have a United States if you are telling some folks that they can't get on the train. There is a cracking point where a society collapses. Bruce Springsteen
united-states grew states
I grew up in the United States. Dominique de Villepin
united
I'm the president of the United States. I'm not the emperor of the United States. Barack Obama
united united-states
We (send) them all over the United States. Judy Dickson