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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics.
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online.
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services.
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts.
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters.
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here,
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof.
among french
There would probably be less of a frenzy among the French public. Michel Patini
among societies
Societies should be judged by how they treat the weakest among them. Maajid Nawaz
among efforts parents people possible rates remain though
The possible slowdown of illicit drug use among young people is encouraging, even though rates of use remain unacceptably high. All of us, especially parents and teachers, need to redouble our efforts Donna Shalala
among aware changed difficult game golf good grown hard high number people perception players respect school
The perception of high school golf a number of years back was not the highest, that it wasn't that hard a sport. That has all changed as the game has grown - especially among young people. There is a lot more respect for the players and the sport. People now are aware of how difficult it is to be good at golf.
among computing game held high jobs parents perception school students widely
The perception among high school students and their parents is that the game is over, that all computing jobs are going overseas. It's an extraordinarily widely held misperception.
among apt businesses carry climate economic economy employees executives focus global growth hiring hopeful improving indicator might optimism perception postponed programs spending stronger top
The perception among C-suite executives that the global economy is getting stronger should be a hopeful indicator for global business. As optimism for the global economic climate improves, top executives are more apt to focus on improving their own businesses by spending for programs that might have been curtailed or postponed and by hiring new employees to carry out their growth plans. Mark Foster
among customers direct microsoft nobody perception products relationship security
The perception among a lot of customers is that nobody understands Microsoft products like Microsoft. Many of them want the security of that direct relationship with Microsoft.
among human impossible point
The point of 'Othello,' among other points, is that it is impossible to know another human being, Patrick Page
among competition forward looking owns vibrant
We are looking forward to a vibrant competition among politicians for these voters. No one owns them. Gary Bauer
approach correct guided lose matters point profound retain sight
The point never to lose sight of is to be guided by the correct thing, as you see it. It's the only way to approach such profound matters and retain your integrity. Charles Kennedy
approach committed good point premise relations
The point is not to lecture. We approach this from the premise that U.S.-China relations are good and we're committed to making them better.
approach athletes closely clubs complement creativity elite horizons improve matches nutrition open perfect pleased science sports team test tests using work
We are pleased to be able to work so closely with Brian, his team of trainers and coaches, and especially the elite athletes that look to TEST Sports Clubs to improve their performance. Our cutting-edge approach to athlete nutrition matches is a perfect complement to TESTs approach of using science and creativity to open new horizons for elite athletes.
approach beginning change grow order
We are at the beginning of the road. In order to grow we need to change the way we approach the way we do business.
approach average caused gasoline levels national past prices record several
We are at levels that in the past several years had caused gasoline prices to approach the $1.70-type national average record levels.
approach batman bit enjoy falls guys left personally seeing superhero vision
As much as I enjoy seeing other guys do the superhero approach to the Batman universe, personally my own vision falls a bit left of center.
approach business certain decide freedom process rushed total versus
Bootstrapping allows you total creative freedom. For example, if you decide to approach your business in a certain way that makes it a two- or three-year process to get to your first product, you can do that, versus being rushed into it by investors. Nick Woodman
approach care eliminate errors focus four game knowing mac mental months season taking three weekend wins
We approach each season knowing that it is going to be a long two months and every game in the MAC is important for us. I think that we need to get three or four wins this weekend and focus on taking care of the little things and eliminate the mental errors that we've been having.
approach barriers national problem repair solve state
We're not going to solve this problem with a patchwork approach at the state level. It's a national problem, and the need is to repair the national system. We're not going to erect barriers between states. Josh Bernstein
cynicism iraq reasons remain took war
My level of cynicism about the reasons that took us to war against Iraq remain just as well-developed as they were before I went. Ted Koppel
cynicism faithless filled hope people perhaps possibilities stems
Cynicism stems from disappointment. Cynical and faithless people were not always like that. They were filled with possibilities and hope as kids. But they tried and perhaps failed.
cynicism government hope led lost quebec time
Cynicism lost and hope won. For the first time, the government of Quebec will be led by a woman. Pauline Marois
cynicism sound
I don't want to sound like the old guy, but cynicism is a potential danger. It colors our way of looking at the world. Bob Newhart
cynicism difference distressed enormous false media parties profoundly reduce
There is a very big difference in where the two parties will take America, ... I sometimes get distressed by our friends in the media because they try to reduce everything to gossip, scandal-mongering and cynicism that I think is profoundly false for this country's future. There is an enormous difference in the two parties. We would go two very different places. Newt Gingrich
cynicism deal great hate perhaps unless worse
I hate cynicism a great deal worse than I do the devil; unless perhaps the two were the same thing
cynicism idealism precedes
Idealism is what precedes experience, cynicism is what follows.
cynicism idealism inevitable
Happiness too is inevitable. Albert Camus
cynicism teach altruism
Live to learn, learn to live, then teach others. Douglas Horton
cynics-and-cynicism
I think to a lot of voters, this kind of thing just reinforces their cynicism. Doug Forrester has campaigned, and is campaigning, in a way to say that 'I'm not like other politicians and I don't do the things they do.' So it cancels out his message.
cynics-and-cynicism level rough voters
Those are pretty rough numbers, the level of cynicism. He just has not communicated with voters in making his case.
developing draft encouraged five forward further inside list looking national picks prospect structure top
We are looking forward to further developing the list structure through the AFL National Draft and are encouraged by the prospect of having five picks inside the top 22.
developing neurons produced record signals technique
We started all this research way back in the early 1990s, developing a technique that allows us to record the electrical signals produced by neurons simultaneously. Miguel Nicolelis
developing experts head state
Where there are two Phd's in a developing country, one is head of state and the other is in exile.
developing figuring parenting
When it comes right down to it, developing a critical sensibility about parenting isn't really about disapproval; it's about honing your own sensibilities, figuring out how you want to parent.
developing growth stagnation
We're going to see at best, stagnation in the market, ... Most of the growth will come from the developing countries. Carlos Ghosn
developing equipment moon programme rational space station
What they're really developing is equipment to do a rational space station and a Moon programme later, Robert Zubrin
developing skills
We're going to have to keep developing our perimeter skills and shooting.
developing either land leaving matter options selling
We're just kind of leaving our options open, ... It's a matter of either developing the land or selling the property.
developing happen looking people stories
I'm really looking forward to developing just really fun, complex, interesting stories about people who happen to be black. Tracie Thoms
law knowing shy
Lawyers are shy of meddling with the Law on their own account: knowing it to be an edged tool of uncertain application, very expensive in the working, and rather remarkable for its properties of close shaving than for its always shaving the right person. Charles Dickens
law justice water
In civil jurisprudence it too often happens that there is so much law, that there is no room for justice, and that the claimant expires of wrong in the midst of right, as mariners die of thirst in the midst of water. Charles Caleb Colton
law justice criminals
The victim to too severe a law is considered as a martyr rather than a criminal.
law land tree
The code of poor laws has at length grown up into a tree, which, like the fabulous Upas, overshadows and poisons the land; unwholesome expedients were the bud, dilemmas and depravities have been the blossom, and danger and despair are the bitter fruit.
law firsts revolution
If we trace the history of most revolutions, we shall find that the first inroads upon the laws have been made by the governors, as often as by the governed.
law genius talent
With the offspring of genius, the law of parturition is reversed; the throes are in the conception, the pleasure in the birth.
law would-be rays
You hear, Eugene?' said Lightwood over his shoulder. 'You are deeply interested in lime.' 'Without lime,' returned that unmoved barrister at law, 'my existence would be unilluminated by a ray of hope.
law principles bleak-house
The one great principle of English law is to make business for itself.
law idiot ass
The law is an ass, an idiot.
quite state sure
We're in a state where we're not quite sure what's happened,
quite unless
Unless he does something drastically amazing, or I play really poorly, I should be quite comfortable.
quite remain vigilant
We're quite pleased, but we have to remain vigilant about this.
quite
We've never done anything quite like this before.
quite swing
I'm small but quite tough. When incensed, I can swing a punch. Lena Headey
quite spoils watching
Let's be honest: nothing spoils 'The Walking Dead' quite like watching 'The Walking Dead.' David Harsanyi
quite since
Since I have been singing for so many years, I don't always need to approach a song quite so laboriously and meticulously. Kate Smith
quite seen
We have a pond, and I've never seen it come up so fast. I haven't seen this much (rain) for quite awhile. Bob Hartley
quite
We're 20 years older, so it's not quite going to be the same. Gary Carter
skepticism taxi sequels
We all approached doing a sequel with great trepidation and skepticism. Jason Biggs
skepticism sceptic
Sceptics are yet the most credulous. Johann Wolfgang von Goethe
skepticism skeptical
We must be skeptical even of our skepticism. Bertrand Russell
skepticism standstill
... scepticismcan never be thoroughly applied, else life would come to a standstill ... George Eliot
skepticism intellect chastity
Skepticism is the chastity of the intellect. George Santayana
skepticism intellect skeptical
Great intellects are skeptical. Friedrich Nietzsche
skepticism
The world started with some skepticism. I think skepticism was warranted,
students sometimes poet
There's been no poet, no great poet in the history of poetry who hasn't also been a great reader of poetry. This is sometimes distressing to my students when I tell them this. Edward Hirsch
students
I've always loved being a student. Elizabeth Olsen
students hard
It's very hard to remain a student in life. Carol Kane
students significant aids
I voted for the Deficit Reduction Package with significant heartburn over the student aid provisions.
students
We're going to take a look at all the qualifications that all of the students bring.
students three year
Three years ago, I had 18 students, ... and this year I have 44.
students wonder enough
One wonders at the docility of the students who evidently must be satisfied enough with the credentials to be uncaring about the lack of education. Jane Jacobs
students impossible affair
To the stern student of affairs, Beirut is a phenomenon, beguiling perhaps, but quite, quite impossible. Jan Morris
students unhappy
There are unhappy parents, students and staff. The only ones who are happy are the administration.