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advanced anticipate approval attention believe candidates compound continue deficit develop disorder fda filing future half lead looking performance pipeline plan pleased positions products progress quarter receiving research second together treatment year
We are pleased with our performance in 2005. The year was highlighted by the filing of the new drug application on NRP104, our lead compound under development, for the treatment of Attention Deficit Hyperactivity Disorder in pediatric populations. We believe that this advancement together with the progress on our other pipeline products positions us well for future growth. Looking forward, we anticipate receiving approval from the FDA on NRP104 in the second half of 2006 and making IND filings on NRP409 and NRP388, the two most advanced candidates in our preclinical pipeline, by the end of the second quarter of 2006. In addition, we plan to continue to develop NRP290, our second most advanced compound, and other drug products in our research pipeline. Krish Krishnan
advanced base broad continuing economics formal gain knowledge latter political reasonable science self skills symbolic together
By a combination of formal training and self study, the latter continuing systematically well into the 1940s, I was able to gain a broad base of knowledge in economics and political science, together with reasonable skills in advanced mathematics, symbolic logic, and mathematical statistics. Herbert A. Simon
advanced aggressive business companies corporate documents manage print providing realized since site tool web
We've always had an aggressive e-commerce strategy. Since our first Web site in 1994, we realized a Web site was more than just a corporate brochure. It had to be an advanced business tool providing everything companies need to design, print and manage their documents online. Dan Beck
advanced affordable based continue create full hosting needs offer product provides recognize satisfy solutions strive technology tools web
Web hosting was the first product in Affinity's portfolio, and it's still a very important part of our business; that's why we continue to strive to create solutions based on the most advanced hosting technology at an affordable price. However, we recognize the need to offer much more than just hosting to satisfy the needs of today's developer, which is why Gate.com also provides a full suite of advanced tools and web services. Jim Collins
advanced body dave destined early given later pay price running season sports strong talk training understanding workouts
What makes Dave so strong is his understanding of training and willingness to pay the price He has given up the other sports and focuses on running now. It's a little too early to talk about what he's destined to do. Later on this season we'll have a better idea. He's doing some advanced workouts and we will have to see how his body reacts. Ed Pancoast
advanced along approach architecture balanced business core customer data delivered earnings geographic key order per pleased proves results revenue second share solid strategy strong technology terms video
We're pleased with the solid revenue and earnings per share results Cisco delivered during its second quarter, but also especially pleased with our strong order momentum. This proves our strategy is working in terms of the convergence of voice, video and data along with our balanced approach to our customer segments, core and advanced technologies, business and technology architecture and key geographic theaters. John Chambers
advanced highly motivated
We're a well-trained organization, highly disciplined and highly motivated .. very technologically advanced here, Peter Ryan
advanced began people popular understand
Over the years, I began to understand that there were a lot of people out there reading physics in popular literature that they could not understand - not because it was too advanced, but because it wasn't advanced enough. Leonard Susskind
advanced pushed rate sales success terms
With these advanced capabilities, we see our success rate in terms of new and follow-up sales being pushed through the roof. Nigel Kelly
alabama applaud church concerning federal law state work
We applaud federal and state law enforcement for their tireless work in making these arrests concerning the Alabama church fires. Patrick Mahoney
alabama along assisting associates call continue difficult efforts fellow guests gulf helping hurricane katrina louisiana opportunity pleased southern victims williams work
We are pleased to have this opportunity to work with Mr. Williams and continue efforts in assisting the victims of Hurricane Katrina along the Mississippi Gulf Coast, ... We continue to call on our associates and guests to keep helping our fellow residents of southern Mississippi, Louisiana and Alabama during these difficult times. Daniel Pearl
alabama grew knows san shop
We?re in San Francisco. She?s from Alabama and she knows where the Goodie Shop is. That?s because she grew up in Arlington. Debbie Smith
alabama focus performance stanford worry
We're going to focus on our own performance and not worry about what Stanford or Alabama is doing. Tanya Chaplin
alabama ask games left people ready worried
We know we have two important games left in the season. A lot of people are going to ask us about Alabama, but we're not worried about Alabama right now. I'm like, 'Alabama who?' It's all about Georgia, and we're just getting ready for these 'Dogs. Antarrious Williams
alabama british english great public revered schools taught time whom
I went to the Alabama public schools at a time when my English teachers, all but one of whom was a woman, taught nothing but the classics. They revered the great British and American writers. Thomas H. Cook
alabama both home north northwest
My ancestors are Highland Scots, and my father's home in north Alabama is so much like northwest Arkansas. I have the same allergies in both places. Ellen Gilchrist
alabama came develop effective given gives ongoing opportunity program recruiting tools university volleyball
When I came to the University of Alabama in 1996, I was given all the tools to develop the volleyball program. We have an effective and ongoing recruiting program that gives us an opportunity to recruit the right kind of kids. Judy Green
alabama-football winner
I ain't never been nothin but a winner. Bear Bryant
children pride men
There is not a manufacturer or tradesman in existence, who would not employ a man who takes a reasonable degree of pride in the appearance of himself and those about him, in preference to a sullen, slovenly fellow, who works doggedly on, regardless of his own clothing and that of his wife and children, and seeming to take pleasure or pride in nothing. Charles Dickens
children father heart
Father Time is not always a hard parent and though he tarries for none of his children, often lays his hand lightly upon those who have used him well; making them old men and women inexorably enough, but leaving their hearts and spirits young and in full vigor. With such people the gray head is but the impression of the old fellow's hand in giving them his blessing, and every wrinkle but a notch in the quiet calendar of a well-spent life. Charles Dickens
children sea play
There is nothing--no, nothing--innocent or good, that dies and is forgotten; let us hold to that faith or none. An infant, a prattling child, dying in the cradle, will live again in the better thoughts of those that loved it, and play its part through them in the redeeming actions of the world, though its body be burnt to ashes or drowned in the deep sea. Charles Dickens
children parenting expectations
In the little world in which children have their existence, whosoever brings them up, there is nothing so finely perceived and so finely felt, as injustice. Charles Dickens
children grieving two
It always grieves me to contemplate the initiation of children into the ways of life when they are scarcely more than infants. It checks their confidence and simplicity, two of the best qualities that heaven gives them, and demands that they share our sorrows before they are capable of entering into our enjoyments. Charles Dickens
children father past
How strange it is that we of the present day are constantly praising that past age which our fathers abused, and as constantly abusing that present age, which our children will praise. Charles Caleb Colton
children knowledge enemy
Religion has treated knowledge sometimes as an enemy, sometimes as a hostage; often as a captive and more often as a child; but knowledge has become of age, and religion must either renounce her acquaintance, or introduce her as a companion and respect her as a friend. Charles Caleb Colton
children gambling parent
Gaming is the child of avarice, but the parent of prodigality. Charles Caleb Colton
children heaven wish
Avarice begets more vices than Priam did children and like Priam survives them all. It starves its keeper to surfeit those who wish him dead, and makes him submit to more mortifications to lose heaven than the martyr undergoes to gain it. Charles Caleb Colton
clay dirty gotta paint rough
I like dirty boys. Mechanics, construction workers, artists who get paint and clay everywhere. They gotta have rough hands. Tamara Feldman
clay
Time is clay; make something. Barbara Sher
clay sun
The same sun that hardens the clay softens the wax. Adam Clarke
clay fields gets holds mow soil stay unsafe vicious water
Right now it's very clay-like soil that holds a lot of water and gets real spongy. The clay soil holds the water so the fields stay wet. We can't mow it and then it's unsafe to play on. It's a vicious cycle. Dan TerAvest
clay felt played spite
I am satisfied, I felt very well in spite of not having played on clay for a long time. Gaston Gaudio
clay county fairly full goal regional summer water
I anticipated we'd have had it done in November. But it will be fairly soon. Our goal is to have full water service, with Clay County Regional Water by the summer months. Ron Walker
clay coming evident felt good grass last match transition week
I felt pretty good coming off of last weekend. The transition coming off grass last week to clay was pretty evident in this match but I thought if I could get through this one I'd be all right. Andy Roddick
clay creation building
In building a statue, a sculptor doesn't keep adding clay to his subject. Actually, he keeps chiseling away at the nonessentials until the truth of his creation is revealed without obstruction. Bruce Lee
clay stones
You cannot expect stone to be as pliable as clay. Anne Bronte
county lack needs seen urban vision
We've all seen the bickering, divisiveness and the lack of sense of vision for urban county government. That all needs to fundamentally change. Jim Newberry
county creation michigan offer state unique wayne
Wayne County and the State of Michigan offer unique opportunities for the creation of the bio-refinery model. Paul Jacobson
county depend elected jobs lip notice property relief service state tax
We want to put elected representatives in Bradford County and our state representatives on notice that their jobs now depend on property tax relief for the residents of Bradford County, that lip service now is not going to get any of them elected any more. Vic Lawson
county districts education effort kids matter provide regular serve student
We want to provide appropriate education for all students, no matter what the student needs. I think all of the districts in the county are really making a concerted effort to serve kids as much as they can in the regular classroom. Steve Smith
county millions saved since
We have saved the county millions since its inception. Paul Tesi
county credible gang information police reliable state verify
We have no credible or reliable information that it's valid, ... We contacted our county gang unit, the State Police gang unit, and they have no information to verify this. William Bailey
county democracy mob numbers whenever
Whenever (the county commissioners) see that, they acquiesce and kowtow to the numbers of voters. It's mob democracy. Al Sevier
county farm people talking today wonder
When you say county farm today people wonder what you are talking about. Larry Hopkins
county couples cutting edge fun local others people realize scene spread step talent word
We want people to gather, have fun and get to know local artists. Young couples and professionals are important to this scene because they know what's cutting edge and spread the word to others. Once people step into our activity, they realize there's a lot of talent here in Polk County that many others haven't yet experienced. Ann Wilson
kids wells understood
Well, as a kid I did not get Shakespeare. I just never understood it. Alanis Morissette
kids winning
You'll never win anything with kids Alan Hansen
kids scientist natural
Kids are natural scientists. Alan Alda
kids mind desperate
In my own mind, I was sort of a desperate kid. Al Purdy
kids gang-members wife
Near my house in Los Angeles is a waterfall. I love to take the wife and kids, but it's also near a sketchy neighborhood. So there's a lot of gang members that hang out at the waterfall. It's like somebody took an Ansel Adams photo and then put a Cypress Hill video inside it. Al Madrigal
kids enjoyed
I went to all the Love-Ins. I took my kids. I enjoyed myself. Al Lewis
kids sure various
We want the kids to do as well as they can. There are so many opportunities (for various activities), and that's good. But, how do we make sure it's not a distraction. Brad Lancaster
kids years add
It doesn't matter how old I get, I always act like an excited five year-old kid with severe ADD and a waddle at Disneyland. Chris Colfer
kids awkward special
My life is an awkward visit from the kid's table while awaiting a History Channel special. Chris Colfer
opportunity deuces letters
Then idiots talk....of Energy. If there is a word in the dictionary under any letter from A to Z that I abominate, it is energy. It is such a conventional superstition, such parrot gabble! What the deuce!....But show me a good opportunity, show me something really worth being energetic about, and I'll show you energy. Charles Dickens
opportunity men often-is
Subtract from the great man all that he owes to opportunity, all that he owes to chance, and all that he gained by the wisdom of his friends and the folly of his enemies, and the giant will often be seen to be a pygmy. Charles Caleb Colton
opportunity female lovers
Fortune, like other females, prefers a lover to a master, and submits with impatience to control; but he that wooes her with opportunity and importunity will seldom court her in vain. Charles Caleb Colton
opportunity mind glory
The road to glory would cease to be arduous if it were trite and trodden; and great minds must be ready not only to take opportunities but to make them. Charles Caleb Colton
opportunity extremity
Our extremities are God's opportunities. Charles Spurgeon
opportunity honor denial
When facing the apparent denial of my request, God gave me the opportunity to honor him by trusting His Word. Charles Spurgeon
opportunity library today
I wouldn’t be the person I am today if it wasn’t for the opportunities the library gave me. Alan Moore
opportunity voice people
It does not do to rely too much on silent majorities, Evey, for silence is a fragile thing, one loud noise, and its gone. But the people are so cowed and disorganised. A few might take the opportunity to protest, but it'll just be a voice crying in the wilderness. Noise is relative to the silence preceding it. The more absolute the hush, the more shocking the thunderclap. Our masters have not heard the people's voice for generations, Evey and it is much, much louder than they care to remember. Alan Moore
opportunity giving people
I want to be able to open up the really good treasures of the Church and Christianity to people, and that's not going to be achieved by shouting at them to convert or they'll go to hell. It's about giving them an opportunity to reimagine Christianity. Alan Green
program explaining ifs
If a listener nods his head when you're explaining your program, wake him up. Alan Perlis
program
The Libyan program recently discovered was far more extensive than was assessed prior to that. David Kay
program programming ifs
If we can't program it, we can't understand it. David Deutsch
program understood ifs
If you can’t program it, you haven’t understood it. David Deutsch
program six students
We started participating in the program in 2004. We started with six students at the Rockledge hospital, and now we have 12 there and two in Melbourne. Sandy Williams
program save sooner
Sooner or later the space program will need to save us by detecting and deflecting an incoming asteroid. Nathan Myhrvold
program advantage admission
Early admission programs tend to advantage the advantaged. Derek Bok
program social social-programs
I don't like a lot of social programs either because it makes you non-productive. Charles Evers
program support turn
We've been able to turn the program around and we're an (Jayhawk East) power. That's just because of the support that we've received. Josh Matthews
rural stigma worry
I worry about the stigma -- especially in rural areas. David Richard
rural
In rural areas, this can be very serious. Erin Matson
teaching knowledge yield
Where thou perceivest knowledge, bend the ear of attention and respect; But yield not further to the teaching, than as thy mind is warranted by reasons. Better is an obstinant disputant, that yieldeth inch by inch, Than the shallow traitor to himself, who surrendereth to half an argument. Charles Caleb Colton
teaching silence statistics
When you have nothing to say, say nothing. Charles Caleb Colton
teacher spring ignorance
Go ye, who rest so placidly upon the sacred Bard who had been young, and when he strung his harp was old, and had never seen the righteous forsaken, or his seed begging their bread; go, Teachers of content and honest pride, into the mine, the mill, the forge, the squalid depths of deepest ignorance, and uttermost abyss of man's neglect, and say can any hopeful plant spring up in air so foul that it extinguishes the soul's bright torch as fast as it is kindled! Charles Dickens
teacher thinking differences
You can't tell a woman who is called by God to teach that she cannot teach the Word of God... So I think the distinction is that there's a difference between the authority of a pastor and a Bible teacher. Charles Stanley
teaching blessing what-matters
If you tell God no because He won't explain the reason He wants you to do something, you are actually hindering His blessing. But when you say yes to Him, all of heaven opens to pour out His goodness and reward your obedience. What matters more than material blessings are the things He is teaching us in our spirit. Charles Stanley
teaching thinking hands
I am content to live and die as the mere repeater of Scriptural teaching - as a person who has thought out nothing and invented nothing - but who concluded that he was to take the message from the lips of God to the best of his ability and simply to be a mouth for God to the people. - mourning much that anything of his own should come between - but never thinking that he was somehow to refine the message or to adapt it to the brilliance of this wonderful century and then to hand it out as being so much his own that he might take some share of the glory of it. Charles Spurgeon
teaching fuel sound
Rest assured that the most fervid revivalism will wear itself out in mere smoke, if it be not maintained by the fuel of teaching.... Sound teaching is the best protection for the heresies which ravage right and left among us. Charles Spurgeon
teaching sticks blisters
If there is any verse that you would like left out of the Bible, that is the verse that ought to stick to you, like a blister, until you really attend to its teaching. Charles Spurgeon
teacher real men
Just what should a young man or woman know to be 'in the know'? Is there, in other words, some inside information, some special taboo, some real lowdown on life and existence that most parents and teachers either don't know or won't tell? Alan Watts